J. Haveman

Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity (2006)

Svensson, J.P., Stalpers, L.J.A., Franken, N.A.P., Haveman, J., Klein, B., ...

Background Radiation is an effective anti-cancer therapy but leads to severe late radiation toxicity in 5%-10% of patients. Assuming that genetic susceptibility impacts this risk, we hypothesized...

Analysis of Gene Expression Using Gene Sets Discriminates Cancer Patients with and without Late Radiation Toxicity (2006)

Svensson, J.P., Stalpers, L.J.A., Franken, N.A.P., Haveman, J., Klein, B., ...

Clonogenic assay of cells in vitro (2006)

Franken, N.A.P., Rodermond, H.M., Stap, J., Haveman, J., Bree, C. Van

Enhanced activity of deoxycytidine kinase after pulsed low dose rate and single dose gamma irradiation (2006)

Sigmond, J., Haveman, J., Castro Kreder, N., Loves, W.J., Bree, C. Van, Franken, N.A.P., ...

Gadolinium enhances the sensitivity of SW-1573 cells for thermal neutron irradiation (2006)

Franken, N.A.P., Bergs, J., Kok, T.T., Kuperus, R.R.N., Stecher-Rasmussen, F., Haveman, J., ...

Effects of cisplatin and gamma-irradiation on cell survival, the induction of chromosomal aberrations and apoptosis in SW-1573 cells (2006)

Bergs, J., Franken, N.A.P., Cate, R. Ten, Bree, C. Van, Haveman, J.

Time course of enhanced activity of deoxycytidine kinase and thymidine kinase 1 and 2 in cultured human squamous lung carcinoma cells, SW-1573, induced by gamma-irradiation (2006)

Haveman, J., Sigmond, J., Bree, C. Van, Franken, N.A.P., Koedooder, C., Peters, G.J.

Endocrine intervention during irradiation does not prevent damage to the thyroid gland (2006)

Santen, H.M. Van, Dijk, J.E. Van, Rodermond, H., Vansenne, F., Endert, E., ...

Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity (2006)

Svensson, J.P., Stalpers, L.J.A., Franken, N.A.P., Haveman, J., Klein, B., ...

The effect of cervical X-irradiation on activity index of thyrocytes and plasma TSH: a pre-clinical model for radiation-induced thyroid damage (2005)

Santen, H.M. Van, Dijk, J.E. Van, Rodermond, H., Vansenne, F., Meertens, N., Haveman, J., ...

Mismatch repair proficiency is not required for radioenhancement by gemcitabine (2005)

Bree, C. Van, Rodermond, H.M., Vos, J. De, Haveman, J., Franken, N.A.P.

Effects of hyperthermia on the central nervous system: what was learnt from animal studies? (2005)

Haveman, J., Sminia, P., Wondergem, J., Zee, J. Van Der

The effect of cervical X-irradiation on activity index of thyrocytes and plasma TSH: a pre-clinical model for radiation-induced thyroid damage (2005)

Santen, H.M. Van, Dijk, J.E. Van, Rodermond, H., Vansenne, F., Meertens, N., Haveman, J., ...

Differential Response to Radiation of TP53-Inactivated Cells by Overexpression of Dominant-Negative Mutant TP53 or HPVE6 (2004)

C. Van Bree, J. Haveman

Franken, N. A. P., van Bree, C. and Haveman, J. Differential Response to Radiation of TP53-Inactivated Cells by Overexpression of Dominant-Negative Mutant TP53 or HPVE6. Radiat. Res. 161, 504–510...

Repair of Potentially Lethal Damage does not Depend on Functional TP53 in Human Glioblastoma Cells (2004)

C. Van Bree, H. M. Rodermond, J. Haveman

van Bree, C., Franken, N. A. P., Rodermond, H. M., Stalpers, L. J. A. and Haveman, J. Repair of Potentially Lethal Damage does not Depend on Functional TP53 in Human Glioblastoma Cells. Radiat. Res....

Effects of hyperthermia on the peripheral nervous system: a review (2004)

Haveman, J., Zee, J. Van Der, Wondergem, J., Hoogeveen, J.F.

Cellular response of X-ray sensitive hamster mutant cell lines to gemcitabine, cisplatin and 5-fluorouracil (2004)

Haveman, J., Castro Kreder, N., Rozermond, H.M., Bree, C. Van, Franken, N.A.P., Stalpers, L.J.A., ...

Repair of potentially lethal damage does not depend on functional TP53 in human glioblastoma cells (2004)

Bree, C. Van, Franken, N.A.P., Rodermond, H.M., Stalpers, L.J.A., Haveman, J.

Differential response to radiation of TP53-inactivated cells by overexpression of dominant-negative mutant TP53 or HPVE6 (2004)

Franken, N.A.P., Bree, C. Van, Haveman, J.

Induction of the early response protein EGR-1 in human tumour cells after ionizing radiation is correlated with a reduction of repair of lethal lesions and an increase of repair of sublethal lesions (2004)

Franken, N.A.P., Cate, R. Ten, Bree, C. Van, Haveman, J.

Effects of gemcitabine on cell survival and chromosome aberrations after pulsed low dose-rate irradiation (2004)

Castro Kreder, N., Bree, C. Van, Franken, N.A.P., Haveman, J.

Enhancement of effects of irradiation by gemcitabine in a glioblastoma cell line and cell line spheroids (2004)

Genc, M., Castro Kreder, N., Stalpers, L.J.A., Haveman, J.

Effects of hyperthermia on the rat bladder: a pre-clinical study on thermometry and functional damage after treatment (2003)

Haveman, J., Smals, O.A.G., Rodermond, H.M.

Colour junctions as predictors of radiosensitivity: X-irradiation combined with gemcitabine in a lung carcinoma cell line (2003)

Castro Kreder, N., Bree, C. Van, Franken, N.A.P., Haveman, J.

Importance of TP53 and RB in the Repair of Potentially Lethal Damage and Induction of Color Junctions after Exposure to Ionizing Radiation (2002)

C. Van Bree, R. Ten Cate, J. Haveman

Franken, N. A. P., van Bree, C., ten Cate, R., van Oven, C. H. and Haveman, J. Importance of TP53 and RB in the Repair of Potentially Lethal Damage and Induction of Color Junctions after Exposure to...

Importance of TP53 and RB in the repair of potentially lethal damage and induction of color junctions after exposure to ionizing radiation (2002)

Franken, N.A.P., Bree, C. Van, Cate, R. Ten, Oven, C.H. Van, Haveman, J.

Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation (2002)

Castro Kreder, N., Bree, C. Van, Peters, G.J., Loves, W.J., Haveman, J.

Chromosome aberrations detected by FISH and correlation with cell survival after irradiation at various dose-rates and after bromodeoxyuridine radiosensitization (2002)

Castro Kreder, N., Bree, C. Van, Franken, N.A.P., Haveman, J.

Sensitivity to ionizing radiation and chemotherapeutic agents in gemcitabine-resistant human tumor cell lines (2002)

Bree, C. Van, Castro Kreder, N., Loves, W.J., Franken, N.A.P., Peters, G.J., Haveman, J.

Wild-type p53-function is not required for hyperthermia-enhanced cytotoxicity of cisplatin (2001)

Bree, C. Van, Franken, N.A.P., Snel, F.A.M., Haveman, J., Bakker, P.J.M.

Radiosensitization by bromodeoxyuridine and hyperthermia: analysis of linear and quadratic parameters of radiation survival curves of two human tumor cell lines (2001)

Franken, N.A.P., Bree, C. Van, Veltmaat, M.A.T., Rodermond, H.M., Haveman, J., Barendsen, G.W.

Exploiting Formality within an Architectural Design Method (2000)

J.M. Armstrong, J. Haveman, S. Paynter

This paper argues that formal methods need to be properly integrated into an architectural design method if they are to be transferred into industrial practice. It outlines a number of issues which...

ADL An Activity Description Language for Real-Time Networks (2000)

J.M. Armstrong, J. Haveman, S. Paynter

Abstract This paper introduces and motivates ADL a new formal notation for the specification of temporal and functional behaviour of concurrent processes. ADL is tailored to be directly compatible...

BrdUrd-induced radiosensitization of two human tumour cell lines at iso-levels of incorporation (2000)

Franken, N.A.P., Bree, C. Van, Kipp, J.B.A., Rodermond, H.M., Haveman, J., Barendsen, G.W.

The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells (2000)

Bree, C. Van, Savonije, J.H., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells (2000)

Bree, C. Van, Savonije, J.H., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells (2000)

Bree, C. Van, Savonije, J.H., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

Inactivation of p53 and of pRb protects human colorectal carcinoma cells against hyperthermia-induced cytotoxicity and apoptosis (1999)

Bree, C. Van, Maat, B. Van Der, Ceha, H.M., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

Effectiveness of 2',2'difluorodeoxycytidine (Gemcitabine) combined with hyperthermia in rat R-1 rhabdomyosarcoma in vitro and in vivo (1999)

Bree, C. Van, Beumer, C., Rodermond, H.M., Haveman, J., Bakker, P.J.M.

Inactivation of p53 and of pRb protects human colorectal carcinoma cells against hyperthermia-induced cytotoxicity and apoptosis (1999)

Bree, C. Van, Maat, B. Van Der, Ceha, H.M., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

Effectiveness of 2',2'difluorodeoxycytidine (Gemcitabine) combined with hyperthermia in rat R-1 rhabdomyosarcanoma in vitro and in vivo (1999)

Bree, C. Van, Beumer, C., Rodermond, H.M., Haveman, J., Bakker, P.J.M.

Hyperthermie in combinatie met radiotherapie (1999)

Zee, J. Van Der, Rhoon, G.C. Van, Haveman, J., Gonzalez Gonzalez, D.

Inactivation of p53 and of pRb protects human colorectal carcinoma cells against hyperthermia-induced cytotoxicity and apoptosis (1999)

Bree, C. Van, Maat, B. Van Der, Ceha, H.M., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

Hyperthermia may decrease the development of telangiectasia after radiotherapy (1998)

Zee, J. Van Der, Wijnmaalen, A.J., Haveman, J., Woudstra, E.

TNF, IL-1 and IL-6 in circulating blood after total-body and localized irradiation in rats (1998)

Haveman, J., Geerdink, A.G., Rodermond, H.M.

Hyperthermia enhances the cytotoxicity and platinum-DNA adduct formation of lobaplatin and oxaliplatin in cultured SW 1573 cells (1997)

Rietbroek, R.C., Haveman, J., Blommaert, F.A., Geerdink, A., Bakker, P.J.M., ...

Lack of thermal enhancement for taxanes in vitro (1997)

Rietbroek, R.C., Katschinski, D.M., Reijers, M.H.E., Robins, H.I., Geerdink, J.H., Tutsch, K., ...

Comment on response to paper by D'Oleire et al: reply to letter to the editor (1997)

Haveman, J.

Radiosensitization by iodo-deoxyuridine in cultured SW-1573 human lung tumor cells: effects on alfa and beta of the linear-quadratic model (1997)

Franken, N.A.P., Bree, C. Van, Streefkerk, J.O., Rodermond, H.M., Kipp, J.B.A., ...

Hyperthermia enhances the cytotoxicity and plantinum-DNA adduct formation of lobaplatin and oxaliplatin in cultured SW 1573 cells (1997)

Rietbroek, R.C., Haveman, J., Blommaert, F.A., Geerdink, A., Bakker, P.J.M., ...

Lack of thermal enhancement for taxanes in vitro (1997)

Rietbroek, R.C., Katschinski, D.M., Reijers, M.H.E., Robins, H.I., Geerdink, A., Tutsch, K., ...

Lack of thermal enhancement for taxanes in vitro (1997)

Rietbroek, R.C., Katschinski, D.M., Reijers, M.H.E., Robins, H.I., Geerdink, J.H., Tutsch, K., ...

Status report: Embedded architectures for second level triggering (EAST) (1994)

Vermeulen, J, Constantin, F, Gheorghe, A, Denes, E, Odor, G, Bock, R K, ...

Embedded architectures for second level triggering (EAST): Status report (1993)

Vermeulen, J, Constantin, F, Gheorghe, A, Denes, E, Odor, G, Bock, R K, ...

The Effects of Protection on the Patter of Trade: A Disaggregated Analysis (a)

Haveman, J., Nair, U.C., Thursby, J.G.

We analyze the effects of protection using disaggregated data. This permits analysis of distinct effects of tariffs and NTBs on trade. Our analysis indicates that tariffs tend to shift trade towards...

What Can We Learn from Bilateral Trade? Gravity and Beyond

Haveman, J., Hummels, D.

Much empirical international trade reserach requires a careful analysis of bilateral trade patterns. In this paper we examine a commonly used technique called the gravity equation. Though the use of...

Radiosensitivity of microscopic tumours of a transplantable mammary adenocarcinoma in mice.

Haveman, J., Jansen, W., Breur, K.

Evidence is presented that microscopic tumours (of a transplantable murine mammary carcinoma, M8013X) grow faster than larger, palpable, tumours. Microscopic tumours are also more radiosensitive than...

Possibilities of an in vivo cell titration method for the assessment of the radiosensitivity of microscopic tumours.

Haveman, J., Breur, K.