NIGHT AERIAL SEARCH FOR AVIATORS DOWNED AT SEA (OPTIMUM SEARCH PROCEDURES), (2005)
GORDON,J. I., Church,P. V., Wasserboehr,J. W., Duntley,S. Q.
Navy tests have demonstrated that the helmet of a Naval aviator downed and afloat at night can be sighted from a searchlight-equipped rescue helicopter if the helmet is covered with a retrodirective...
BIOINFORMATICS ORIGINAL PAPER Genome (2004)
B. P. Westover, J. D. Buhler, J. L. Sonnenburg, J. I. Gordon
Motivation: Annotation of operons in a bacterial genome is an important step in determining an organism’s transcriptional regulatory program. While extensive studies of operon structure have been...
Operon prediction without a training set (2004)
Westover, B. P., Buhler, J. D., Sonnenburg, J. L., Gordon, J. I.
Motivation: Annotation of operons in a bacterial genome is an important step in determining an organism's transcriptional regulatory program. While extensive studies of operon structure have been...
Operon prediction without a training set (2004)
Westover, B. P., Buhler, J. D., Sonnenburg, J. L., Gordon, J. I.
Motivation: Annotation of operons in a bacterial genome is an important step in determining an organism's transcriptional regulatory program. While extensive studies of operon structure have been...
The equilibrium radiance model, which assumes constancy in the source function along the path of sight, predicts equilibrium radiance as a function of the angle from the sun. Measurements made at all...
Wong, M. H., Huelsken, J., Birchmeier, W., Gordon, J. I.
Studies of chimeric mice have disclosed that the stem cell hierarchy in the small intestinal epithelium is established during formation of its proliferative units (crypts of Lieberkuhn). This process...
Relative resistance to Phytophthora spp. among six rootstocks used for waxflower production (1999)
O'Sullivan, G. J., Galea, V. J., Gordon, J. I., Fletcher, R. J.
Chamelaucium leaves as a bait for isolating Phytophthora from soil (1999)
O'Sullivan, G. J., Galea, V. J., Gordon, J. I., Fletcher, R. J.
Conquering disease in waxflower (1999)
O'Sullivan, G. J., Galea, V. J., Gordon, J. I., Fletcher, R. J.
Relative resistance to Phytophthora spp. among six rootstocks used for waxflower production (1999)
O'Sullivan, G. J., Galea, V. J., Gordon, J. I., Fletcher, R. J.
Chamelaucium leaves as a bait for isolating Phytophthora from soil (1999)
O'Sullivan, G. J., Galea, V. J., Gordon, J. I., Fletcher, R. J.
Conquering disease in waxflower (1999)
O'Sullivan, G. J., Galea, V. J., Gordon, J. I., Fletcher, R. J.
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. (1997)
Fazeli, A, Dickinson, S L, Hermiston, M L, Tighe, R V, Steen, R G, Small, C G, ...
The DCC (Deleted in colorectal cancer) gene was first identified as a candidate for a tumour-suppressor gene on human chromosome 18q. More recently, in vitro studies in rodents have provided evidence...
Wong, M H, Hermiston, M L, Syder, A J, Gordon, J I
Mutations of the human adenomatosis polyposis coli (APC) gene are associated with the development of familial as well as sporadic intestinal neoplasia. To examine the in vivo function of APC, 129/Sv...
Simon, T C, Roberts, L J, Gordon, J I
A sequence of epithelial cell proliferation, allocation to four principal lineages, migration-associated differentiation, and cell loss occurs along the crypt-villus axis of the mouse intestine. The...
Falk, P G, Bry, L, Holgersson, J, Gordon, J I
Helicobacter pylori is a human pathogen associated with the development of gastric and duodenal ulcers and gastric adenocarcinoma. To test the hypothesis that the human Lewis(b) blood group antigen...
Kim, S H, Roth, K A, Coopersmith, C M, Pipas, J M, Gordon, J I
The four principal gut epithelial cell lineages undergo continuous and rapid renewal during a geographically well-organized migration along the crypt-to-villus axis. The molecules that regulate their...
Toxicity of myristic acid analogs toward African trypanosomes.
Doering, T L, Lu, T, Werbovetz, K A, Gokel, G W, Hart, G W, Gordon, J I, ...
New drugs are needed for treatment of diseases caused by African trypanosomes. One possible target for chemotherapy is the biosynthesis of the glycosyl phosphatidyl-inositol (GPI) of this parasite's...
Johnson, D R, Cok, S J, Feldmann, H, Gordon, J I
Several essential Saccharomyces cerevisiae proteins require myristate to be covalently bound to their amino-terminal glycine for biological activity. Protein N-myristoylation is catalyzed by...
Paneth cell differentiation in the developing intestine of normal and transgenic mice.
Bry, L, Falk, P, Huttner, K, Ouellette, A, Midtvedt, T, Gordon, J I
Paneth cells represent one of the four major epithelial lineages in the mouse small intestine. It is the only lineage that migrates downward from the stem-cell zone located in the lower portion of...
Lodge, J K, Jackson-Machelski, E, Toffaletti, D L, Perfect, J R, Gordon, J I
Cryptococcus neoformans is a major cause of systemic fungal infection in immunocompromised patients. Myristoyl-CoA:protein N-myristoyltransferase (Nmt) catalyzes the transfer of myristate (C14:0)...
Rudnick, D A, Rocque, W J, McWherter, C A, Toth, M V, Jackson-Machelski, E, Gordon, J I
Nmt1p (EC 2.3.1.97) catalyzes the transfer of myristate (C14:0) from coenzyme A to the N-terminal glycine residue of a variety of eukaryotic cellular and viral proteins. Our recent studies of the...
Falk, P, Roth, K A, Borén, T, Westblom, T U, Gordon, J I, Normark, S
Helicobacter pylori is a microaerophilic bacterium found in the stomach of asymptomatic humans as well as patients with acid peptic disease and gastric adenocarcinoma. We have developed an in situ...
Hermiston, M L, Green, R P, Gordon, J I
An in vivo system has been developed for examining the effects of wild-type or mutant proteins on cell fate determination in the mouse intestinal epithelium or on the proliferation and...
Chandrasekaran, C, Gordon, J I
The proliferation and differentiation programs of gut epithelial cells are expressed rapidly and perpetually along an anatomically well defined pathway. The mouse intestine thus provides an excellent...
Analogs of palmitoyl-CoA that are substrates for myristoyl-CoA:protein N-myristoyltransferase.
Rudnick, D A, Lu, T, Jackson-Machelski, E, Hernandez, J C, Li, Q, Gokel, G W, ...
Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p; EC 2.3.1.97) is an essential enzyme that is highly selective for myristoyl-CoA in vivo. It is unclear why myristate...
Cohn, S M, Roth, K A, Birkenmeier, E H, Gordon, J I
We have used liver fatty acid-binding protein/human growth hormone (L-FABP/hGH) fusion genes to explore the temporal and spatial differentiation of intestinal epithelial cells in 1- to 12-month-old...
Bryant, M L, Ratner, L, Duronio, R J, Kishore, N S, Devadas, B, Adams, S P, ...
Covalent linkage of myristate (tetradecanoate; 14:0) to the NH2-terminal glycine residue of the human immunodeficiency virus 1 (HIV-1) 55-kDa gag polyprotein precursor (Pr55gag) is necessary for its...
Roth, K A, Hermiston, M L, Gordon, J I
Transgenes, composed of elements of the 5' nontranscribed region of the liver fatty acid-binding protein (L-FABP) gene linked to various reporters, have previously been used to explore the cellular,...
G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.
Mumby, S M, Heukeroth, R O, Gordon, J I, Gilman, A G
Myristoylation of seven different alpha subunits of guanine nucleotide-binding regulatory proteins (G proteins) was examined by expressing these proteins in monkey kidney COS cells. Metabolic...
Duronio, R J, Jackson-Machelski, E, Heuckeroth, R O, Olins, P O, Devine, C S, Yonemoto, W, ...
Protein N-myristoylation refers to the covalent attachment of a myristoyl group (C14:0), via amide linkage, to the NH2-terminal glycine residue of certain cellular and viral proteins....
The mammalian intestinal epithelium undergoes continuous and rapid renewal of its four principal terminally differentiated cell types. These cells arise from multipotent stem cells located at or near...
Johnson, D R, Cox, A D, Solski, P A, Devadas, B, Adams, S P, Leimgruber, R M, ...
Covalent attachment of myristic acid (C14:0) to the NH2-terminal glycine residue of a number of cellular, viral, and oncogene-encoded proteins is essential for full expression of their biological...
Cok, S J, Martin, C G, Gordon, J I
Inositol regulates transcription of Saccharomyces cerevisiae genes required for de novo synthesis of acylCoAs and phospholipids. Removal of inositol results in transcriptional activation by...
Sukupolvi, S, Lorenz, R G, Gordon, J I, Bian, Z, Pfeifer, J D, Normark, S J, ...
The factors that mediate binding of Salmonella typhimurium to small intestinal epithelial cells have not been fully characterized. In this paper we demonstrate that elimination of production of thin...
Green, R P, Birkenmeier, E H, Beamer, W G, Maltais, L J, Gordon, J I
Thyroid hormone has been implicated as an important factor in rodent development. We have used a strain of mice with a recessive mutation producing congenital primary hypothyroidism (C.RF/J-hyt/+) to...
Heuckeroth, R O, Glaser, L, Gordon, J I
Myristoyl-CoA:protein N-myristoyltransferase (NMT), the enzyme that transfers the myristoyl (14:0) moiety from myristoyl CoA thioester to nascent proteins, is remarkably specific for both peptide and...
Sweetser, D A, Hauft, S M, Hoppe, P C, Birkenmeier, E H, Gordon, J I
The rat intestinal fatty acid binding protein (I-FABP) gene exhibits cell-specific as well as regional differences in its expression within the continuously regenerating small intestinal epithelium....
Rubin, D C, Ong, D E, Gordon, J I
We have examined the pattern of differentiation of the small intestinal epithelium in fetal rats during the 17th through 21st days of gestation. Five genes expressed in late fetal, neonatal, and...
A number of viral and cellular proteins contain covalently bound lipid. In a subset of these acyl proteins, the 14-carbon saturated fatty acid myristic acid is attached through an amide linkage to an...
Sacchettini, J C, Gordon, J I, Banaszak, L J
Rat intestinal fatty acid binding protein (I-FABP) is a member of a family of cytoplasmic hydrophobic ligand-binding proteins. To gain insights about the contribution of bound fatty acid to I-FABP's...
Bryant, M L, Heuckeroth, R O, Kimata, J T, Ratner, L, Gordon, J I
Myristoyl-CoA:protein N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the cotranslational linkage of myristate to the N-terminal glycine residues of several cellular, viral, and oncoproteins. We...
Davidson, N O, Drewek, M J, Gordon, J I, Elovson, J
We previously reported that intestinal apo B48 synthesis in the rat was unaltered by dietary triglyceride intake but demonstrated regulation in response to biliary lipid availability. Studies are now...
Globin gene expression in erythroid human fetal liver cells.
Ley, T J, Maloney, K A, Gordon, J I, Schwartz, A L
We measured steady-state levels of the human globin mRNAs in liver samples from several mid-gestational fetuses. RNA from the epsilon, gamma, beta, zeta, theta, and alpha globin genes were present in...
Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.
Towler, D A, Adams, S P, Eubanks, S R, Towery, D S, Jackson-Machelski, E, Glaser, L, ...
Myristoyl CoA:protein N-myristoyltransferase (NMT) catalyzes the addition of myristic acid to the amino-terminal glycine residues of a number of eukaryotic proteins. Recently, we developed a...
Mouse and rat small intestinal cDNA libraries were screened for recombinants derived from mRNAs whose concentration changed during the transition from suckling to weaning. cDNAs transcribed from a...
Cloning of a cDNA encoding rat intestinal fatty acid binding protein.
Alpers, D H, Strauss, A W, Ockner, R K, Bass, N M, Gordon, J I
Intestinal fatty acid binding protein mRNA is one of the most abundant mRNA species in the rat small intestinal epithelium. RNA transfer blot analyses disclosed that the mRNA encoding intestinal...
Coordinate regulation of two estrogen-dependent genes in avian liver.
Wiskocil, R, Bensky, P, Dower, W, Goldberger, R F, Gordon, J I, Deeley, R G
Livers of egg-laying species contain abundant mRNAs encoded by both estrogen-responsive and constitutively expressed genes. We have recently constructed cDNA clones from three members of the abundant...
Li, E, Demmer, L A, Sweetser, D A, Ong, D E, Gordon, J I
The primary structure of rat cellular retinol-binding protein (CRBP) II has been determined from a cloned cDNA. Alignment of this 134-amino acid, 15,580-Da polypeptide with rat CRBP revealed that 75...
Tissue-specific expression and developmental regulation of the rat apolipoprotein B gene.
Demmer, L A, Levin, M S, Elovson, J, Reuben, M A, Lusis, A J, Gordon, J I
Expression of the apolipoprotein B (apoB) gene was examined in a variety of fetal, neonatal, and adult rat tissues by probing RNA blots with a cloned rat apoB cDNA. Among 10 adult male tissues...
Elshourbagy, N A, Boguski, M S, Liao, W S, Jefferson, L S, Gordon, J I, Taylor, J M
Rat apolipoproteins (apo-) A-IV and A-I share many structural similarities, the most notable of which is a domain of repeated docosapeptides with amphipathic helical potential. Although the genes for...
Boguski, M S, Elshourbagy, N, Taylor, J M, Gordon, J I
Apolipoprotein (apo) A-IV is a 46,000 Mr protein that is a major component of rat high density lipoproteins and chylomicrons. We have isolated, from a rat intestinal cDNA library, a full-length apo...
Primary induction of vitellogenin mRNA in the rooster by 17beta-estradiol.
Burns, A T, Deeley, R G, Gordon, J I, Udell, D S, Mullinix, K P, Goldberger, R F
We have studied the kinetics of vitellogenin mRNA accumulation in rooster liver after a primary injection of 17beta-estradiol. The levels of vitellogenin mRNA have been determined both by...
Comparative analysis of repeated sequences in rat apolipoproteins A-I, A-IV, and E.
Boguski, M S, Elshourbagy, N, Taylor, J M, Gordon, J I
To understand the structural, functional, and evolutionary relationships among the principal protein components of rat high density lipoprotein particles, we undertook a systematic comparative...
Edelstein, C, Gordon, J I, Vergani, C A, Catapano, A L, Pietrini, V, Scanu, A M
We examined the ability of the plasma of a 52-yr-old male Tangier patient to effect the conversion of radiolabeled pro-apolipoprotein A-I (apo A-I), isolated from hepatoma cell culture media, into...
Mullinix, K P, Wetekam, W, Deeley, R G, Gordon, J I, Meyers, M, Kent, K A, ...
We have investigated the estrogen-mediated induction of vitellogenin synthesis in rooster liver. We compared the concentrations of vitellogenin messenger RNA (mRNA) in the liver with the...
Duronio, R J, Reed, S I, Gordon, J I
We have isolated cDNAs encoding human myristoyl-CoA:protein N-myristoyltransferase (NMT, EC 2.3.1.97) by complementing the nmtl-181 mutation of Saccharomyces cerevisiae, which causes...
Wong, M H, Hermiston, M L, Syder, A J, Gordon, J I
Mutations of the human adenomatosis polyposis coli (APC) gene are associated with the development of familial as well as sporadic intestinal neoplasia. To examine the in vivo function of APC, 129/Sv...
Simon, T C, Roberts, L J, Gordon, J I
A sequence of epithelial cell proliferation, allocation to four principal lineages, migration-associated differentiation, and cell loss occurs along the crypt-villus axis of the mouse intestine. The...
Falk, P G, Bry, L, Holgersson, J, Gordon, J I
Helicobacter pylori is a human pathogen associated with the development of gastric and duodenal ulcers and gastric adenocarcinoma. To test the hypothesis that the human Lewis(b) blood group antigen...
Kim, S H, Roth, K A, Coopersmith, C M, Pipas, J M, Gordon, J I
The four principal gut epithelial cell lineages undergo continuous and rapid renewal during a geographically well-organized migration along the crypt-to-villus axis. The molecules that regulate their...
Toxicity of myristic acid analogs toward African trypanosomes.
Doering, T L, Lu, T, Werbovetz, K A, Gokel, G W, Hart, G W, Gordon, J I, ...
New drugs are needed for treatment of diseases caused by African trypanosomes. One possible target for chemotherapy is the biosynthesis of the glycosyl phosphatidyl-inositol (GPI) of this parasite's...
Johnson, D R, Cok, S J, Feldmann, H, Gordon, J I
Several essential Saccharomyces cerevisiae proteins require myristate to be covalently bound to their amino-terminal glycine for biological activity. Protein N-myristoylation is catalyzed by...
Paneth cell differentiation in the developing intestine of normal and transgenic mice.
Bry, L, Falk, P, Huttner, K, Ouellette, A, Midtvedt, T, Gordon, J I
Paneth cells represent one of the four major epithelial lineages in the mouse small intestine. It is the only lineage that migrates downward from the stem-cell zone located in the lower portion of...
Lodge, J K, Jackson-Machelski, E, Toffaletti, D L, Perfect, J R, Gordon, J I
Cryptococcus neoformans is a major cause of systemic fungal infection in immunocompromised patients. Myristoyl-CoA:protein N-myristoyltransferase (Nmt) catalyzes the transfer of myristate (C14:0)...
Rudnick, D A, Rocque, W J, McWherter, C A, Toth, M V, Jackson-Machelski, E, Gordon, J I
Nmt1p (EC 2.3.1.97) catalyzes the transfer of myristate (C14:0) from coenzyme A to the N-terminal glycine residue of a variety of eukaryotic cellular and viral proteins. Our recent studies of the...
Falk, P, Roth, K A, Borén, T, Westblom, T U, Gordon, J I, Normark, S
Helicobacter pylori is a microaerophilic bacterium found in the stomach of asymptomatic humans as well as patients with acid peptic disease and gastric adenocarcinoma. We have developed an in situ...
Hermiston, M L, Green, R P, Gordon, J I
An in vivo system has been developed for examining the effects of wild-type or mutant proteins on cell fate determination in the mouse intestinal epithelium or on the proliferation and...
Chandrasekaran, C, Gordon, J I
The proliferation and differentiation programs of gut epithelial cells are expressed rapidly and perpetually along an anatomically well defined pathway. The mouse intestine thus provides an excellent...
Analogs of palmitoyl-CoA that are substrates for myristoyl-CoA:protein N-myristoyltransferase.
Rudnick, D A, Lu, T, Jackson-Machelski, E, Hernandez, J C, Li, Q, Gokel, G W, ...
Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p; EC 2.3.1.97) is an essential enzyme that is highly selective for myristoyl-CoA in vivo. It is unclear why myristate...
Cohn, S M, Roth, K A, Birkenmeier, E H, Gordon, J I
We have used liver fatty acid-binding protein/human growth hormone (L-FABP/hGH) fusion genes to explore the temporal and spatial differentiation of intestinal epithelial cells in 1- to 12-month-old...
Bryant, M L, Ratner, L, Duronio, R J, Kishore, N S, Devadas, B, Adams, S P, ...
Covalent linkage of myristate (tetradecanoate; 14:0) to the NH2-terminal glycine residue of the human immunodeficiency virus 1 (HIV-1) 55-kDa gag polyprotein precursor (Pr55gag) is necessary for its...
Roth, K A, Hermiston, M L, Gordon, J I
Transgenes, composed of elements of the 5' nontranscribed region of the liver fatty acid-binding protein (L-FABP) gene linked to various reporters, have previously been used to explore the cellular,...
G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.
Mumby, S M, Heukeroth, R O, Gordon, J I, Gilman, A G
Myristoylation of seven different alpha subunits of guanine nucleotide-binding regulatory proteins (G proteins) was examined by expressing these proteins in monkey kidney COS cells. Metabolic...
Duronio, R J, Jackson-Machelski, E, Heuckeroth, R O, Olins, P O, Devine, C S, Yonemoto, W, ...
Protein N-myristoylation refers to the covalent attachment of a myristoyl group (C14:0), via amide linkage, to the NH2-terminal glycine residue of certain cellular and viral proteins....
The mammalian intestinal epithelium undergoes continuous and rapid renewal of its four principal terminally differentiated cell types. These cells arise from multipotent stem cells located at or near...
Johnson, D R, Cox, A D, Solski, P A, Devadas, B, Adams, S P, Leimgruber, R M, ...
Covalent attachment of myristic acid (C14:0) to the NH2-terminal glycine residue of a number of cellular, viral, and oncogene-encoded proteins is essential for full expression of their biological...
Cok, S J, Martin, C G, Gordon, J I
Inositol regulates transcription of Saccharomyces cerevisiae genes required for de novo synthesis of acylCoAs and phospholipids. Removal of inositol results in transcriptional activation by...
Sukupolvi, S, Lorenz, R G, Gordon, J I, Bian, Z, Pfeifer, J D, Normark, S J, ...
The factors that mediate binding of Salmonella typhimurium to small intestinal epithelial cells have not been fully characterized. In this paper we demonstrate that elimination of production of thin...
Green, R P, Birkenmeier, E H, Beamer, W G, Maltais, L J, Gordon, J I
Thyroid hormone has been implicated as an important factor in rodent development. We have used a strain of mice with a recessive mutation producing congenital primary hypothyroidism (C.RF/J-hyt/+) to...
Heuckeroth, R O, Glaser, L, Gordon, J I
Myristoyl-CoA:protein N-myristoyltransferase (NMT), the enzyme that transfers the myristoyl (14:0) moiety from myristoyl CoA thioester to nascent proteins, is remarkably specific for both peptide and...
Sweetser, D A, Hauft, S M, Hoppe, P C, Birkenmeier, E H, Gordon, J I
The rat intestinal fatty acid binding protein (I-FABP) gene exhibits cell-specific as well as regional differences in its expression within the continuously regenerating small intestinal epithelium....
Rubin, D C, Ong, D E, Gordon, J I
We have examined the pattern of differentiation of the small intestinal epithelium in fetal rats during the 17th through 21st days of gestation. Five genes expressed in late fetal, neonatal, and...
A number of viral and cellular proteins contain covalently bound lipid. In a subset of these acyl proteins, the 14-carbon saturated fatty acid myristic acid is attached through an amide linkage to an...
Sacchettini, J C, Gordon, J I, Banaszak, L J
Rat intestinal fatty acid binding protein (I-FABP) is a member of a family of cytoplasmic hydrophobic ligand-binding proteins. To gain insights about the contribution of bound fatty acid to I-FABP's...
Bryant, M L, Heuckeroth, R O, Kimata, J T, Ratner, L, Gordon, J I
Myristoyl-CoA:protein N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the cotranslational linkage of myristate to the N-terminal glycine residues of several cellular, viral, and oncoproteins. We...
Davidson, N O, Drewek, M J, Gordon, J I, Elovson, J
We previously reported that intestinal apo B48 synthesis in the rat was unaltered by dietary triglyceride intake but demonstrated regulation in response to biliary lipid availability. Studies are now...
Globin gene expression in erythroid human fetal liver cells.
Ley, T J, Maloney, K A, Gordon, J I, Schwartz, A L
We measured steady-state levels of the human globin mRNAs in liver samples from several mid-gestational fetuses. RNA from the epsilon, gamma, beta, zeta, theta, and alpha globin genes were present in...
Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.
Towler, D A, Adams, S P, Eubanks, S R, Towery, D S, Jackson-Machelski, E, Glaser, L, ...
Myristoyl CoA:protein N-myristoyltransferase (NMT) catalyzes the addition of myristic acid to the amino-terminal glycine residues of a number of eukaryotic proteins. Recently, we developed a...
Mouse and rat small intestinal cDNA libraries were screened for recombinants derived from mRNAs whose concentration changed during the transition from suckling to weaning. cDNAs transcribed from a...
Cloning of a cDNA encoding rat intestinal fatty acid binding protein.
Alpers, D H, Strauss, A W, Ockner, R K, Bass, N M, Gordon, J I
Intestinal fatty acid binding protein mRNA is one of the most abundant mRNA species in the rat small intestinal epithelium. RNA transfer blot analyses disclosed that the mRNA encoding intestinal...
Coordinate regulation of two estrogen-dependent genes in avian liver.
Wiskocil, R, Bensky, P, Dower, W, Goldberger, R F, Gordon, J I, Deeley, R G
Livers of egg-laying species contain abundant mRNAs encoded by both estrogen-responsive and constitutively expressed genes. We have recently constructed cDNA clones from three members of the abundant...
Li, E, Demmer, L A, Sweetser, D A, Ong, D E, Gordon, J I
The primary structure of rat cellular retinol-binding protein (CRBP) II has been determined from a cloned cDNA. Alignment of this 134-amino acid, 15,580-Da polypeptide with rat CRBP revealed that 75...
Tissue-specific expression and developmental regulation of the rat apolipoprotein B gene.
Demmer, L A, Levin, M S, Elovson, J, Reuben, M A, Lusis, A J, Gordon, J I
Expression of the apolipoprotein B (apoB) gene was examined in a variety of fetal, neonatal, and adult rat tissues by probing RNA blots with a cloned rat apoB cDNA. Among 10 adult male tissues...
Elshourbagy, N A, Boguski, M S, Liao, W S, Jefferson, L S, Gordon, J I, Taylor, J M
Rat apolipoproteins (apo-) A-IV and A-I share many structural similarities, the most notable of which is a domain of repeated docosapeptides with amphipathic helical potential. Although the genes for...
Boguski, M S, Elshourbagy, N, Taylor, J M, Gordon, J I
Apolipoprotein (apo) A-IV is a 46,000 Mr protein that is a major component of rat high density lipoproteins and chylomicrons. We have isolated, from a rat intestinal cDNA library, a full-length apo...
Primary induction of vitellogenin mRNA in the rooster by 17beta-estradiol.
Burns, A T, Deeley, R G, Gordon, J I, Udell, D S, Mullinix, K P, Goldberger, R F
We have studied the kinetics of vitellogenin mRNA accumulation in rooster liver after a primary injection of 17beta-estradiol. The levels of vitellogenin mRNA have been determined both by...
Comparative analysis of repeated sequences in rat apolipoproteins A-I, A-IV, and E.
Boguski, M S, Elshourbagy, N, Taylor, J M, Gordon, J I
To understand the structural, functional, and evolutionary relationships among the principal protein components of rat high density lipoprotein particles, we undertook a systematic comparative...
Edelstein, C, Gordon, J I, Vergani, C A, Catapano, A L, Pietrini, V, Scanu, A M
We examined the ability of the plasma of a 52-yr-old male Tangier patient to effect the conversion of radiolabeled pro-apolipoprotein A-I (apo A-I), isolated from hepatoma cell culture media, into...
Mullinix, K P, Wetekam, W, Deeley, R G, Gordon, J I, Meyers, M, Kent, K A, ...
We have investigated the estrogen-mediated induction of vitellogenin synthesis in rooster liver. We compared the concentrations of vitellogenin messenger RNA (mRNA) in the liver with the...
Duronio, R J, Reed, S I, Gordon, J I
We have isolated cDNAs encoding human myristoyl-CoA:protein N-myristoyltransferase (NMT, EC 2.3.1.97) by complementing the nmtl-181 mutation of Saccharomyces cerevisiae, which causes...