J. J. Bogaards

Quantification of human hepatic glutathione S-transferases.

Van Ommen, B, Bogaards, J J, Peters, W H, Blaauboer, B, Van Bladeren, P J

Human hepatic glutathione S-transferase (GST) subunits were characterized and quantified with the aid of a recently developed h.p.l.c. method. In 20 hepatic tissue specimens the absolute amounts of...

Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea.

Bogaards, J J, Van Ommen, B, Van Bladeren, P J

Eight dimeric isoenzymes of glutathione S-transferase (GST) were purified from liver, kidney and testis of the Syrian golden hamster, using S-hexylglutathione affinity chromatography and...

Irreversible inhibition of rat glutathione S-transferase 1-1 by quinones and their glutathione conjugates. Structure-activity relationship and mechanism.

Van Ommen, B, Ploemen, J H, Bogaards, J J, Monks, T J, Gau, S S, Van Bladeren, P J

The irreversible inhibition of the rat glutathione S-transferase (GST) isoenzyme 1-1 by a series of halogenated 1,4-benzoquinones and their GSH conjugates was studied quantitatively by analysing the...

Quantification of human hepatic glutathione S-transferases.

Van Ommen, B, Bogaards, J J, Peters, W H, Blaauboer, B, Van Bladeren, P J

Human hepatic glutathione S-transferase (GST) subunits were characterized and quantified with the aid of a recently developed h.p.l.c. method. In 20 hepatic tissue specimens the absolute amounts of...

Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea.

Bogaards, J J, Van Ommen, B, Van Bladeren, P J

Eight dimeric isoenzymes of glutathione S-transferase (GST) were purified from liver, kidney and testis of the Syrian golden hamster, using S-hexylglutathione affinity chromatography and...

Irreversible inhibition of rat glutathione S-transferase 1-1 by quinones and their glutathione conjugates. Structure-activity relationship and mechanism.

Van Ommen, B, Ploemen, J H, Bogaards, J J, Monks, T J, Gau, S S, Van Bladeren, P J

The irreversible inhibition of the rat glutathione S-transferase (GST) isoenzyme 1-1 by a series of halogenated 1,4-benzoquinones and their GSH conjugates was studied quantitatively by analysing the...