J. J. L. Iversen

Glucose uptake and growth of glucose-limited chemostat cultures of Aspergillus niger and a disruptant lacking MstA, a high-affinity glucose transporter (2007)

Jorgensen, T.R., VanKuyk, P.A., Poulsen, B.R., Ruijter, G.J.G., Visser, J., Iversen, J.J.L.

Increased NADPH concentration obtained by metabolic engineering of the pentose phosphate pathway in Aspergillus niger (2005)

Poulsen, B.R., Nohr, J., Douthwaite, S., Hansen, L.V., Iversen, J.J.L., Visser, J., ...

Many biosynthetic reactions and bioconversions are limited by low availability of NADPH. With the purpose of increasing the NADPH concentration and/or the flux through the pentose phosphate pathway...

Isolation of a fluffy mutant of Aspergillus niger from chemostat culture and its potential use as a morphologically stable host for protein production (2004)

Poulsen, B.R., Ruijter, G.J.G., Schuleit, T., Visser, J., Iversen, J.J.L.

Chemostat cultivation of Aspergillus niger and other filamentous fungi is often hindered by the spontaneous appearance of morphologic mutants. Using the Variomixing bioreactor and applying different...

Fast response filter module with plug flow of filtrate for on-line sampling from submerged cultures of filamentous fungi (2004)

Poulsen, B.R., Ruijter, G.J.G., Panneman, H., Iversen, J.J.L., Visser, J.

Automatic and accurate sampling is both convenient and sometimes necessary to obtain detailed information about cell cultures. We developed an autoclavable sampling system in which culture broth was...

Characterization of nerolidol biotransformation based on indirect on-line estimation of biomass concentration and physiological state in batch cultures of Aspergillus niger (2004)

Ruijter, G.J.G., Visser, J., Iversen, J.J.L.

Biotransformation of the sesquiterpenoid trans-nerolidol by Aspergillus niger has previously been investigated as a method for the formation of 12-hydroxy- trans-nerolidol, a precursor in the...

Determination of first order rate constants by natural logarithm of the slope plot exemplified by analysis of Aspergillus niger in batch culture (2003)

Poulsen, B.R., Ruiter, G., Visser, J., Iversen, J.J.L.

Finding rate constants from experimental data is often difficult because of offset and noise. A computer program was developed to average experimental data points, reducing the effect of noise, and...