Hydrothermal Systems in Small Ocean Planets (2007)
Vance, S., Harnmeijer, J., Kimura, J., Hussmann, H., Brown, M.
We examine means for driving hydrothermal activity in extraterrestrial oceans on planets and satellites of less than one Earth mass, with implications for sustaining a low level of biological...
Effect of prostaglandin E2on ATP-induced Ca2+responses in human THP-1 monocytic cells (2007)
Goto, M, Murakawa, M, Kimura, J, Matsuoka, I
No abstract available.
Ishizuka, O., Kimura, J., Li, Y.B., Stern, R.J., Taylor, R.N., Ohara, Y., ...
A remarkable record of early arc volcanism in the Izu–Bonin–Mariana (IBM) arc is exposed in and around the Bonin Islands, an uplifted segment of the IBM forearc. New 40Ar/39Ar dating results...
Volcanism in Response to Plate Flexure (2006)
Hirano, N., Takahashi, E., Yamamoto, J., Abe, N., Ingle, S.P., Kaneoka, I., ...
Volcanism on Earth is known to occur in three tectonic settings: divergent plate boundaries (such as mid-ocean ridges), convergent plate boundaries (such as island arcs), and hot spots. We report...
The orbicularis oculi reflexes (1999)
Berardelli, A., Cruccu, G., Kimura, J., Ongerboer De Visser, B.W., Valls-Sole, J.
Identification of septins in neurofibrillary tangles in alzheimers disease (1998)
Kinoshita, A., Kinshita, M., Akiyama, H., Tomimoto, H., Akiguchi, I., Kumar, S., ...
Identification of septins in neurofibrillary tangles in alzheimers disease (1998)
Kinoshita, A., Kinshita, M., Akiyama, H., Tomimoto, H., Akiguchi, I., Kumar, S., ...
Hata, K, Kimura, J, Miki, H, Toyosawa, T, Nakamura, T, Katsu, K
ER-30346 is a novel oral triazole with a broad spectrum of potent activity against a wide range of fungi. ER-30346, with MICs at which 90% of the strains tested are inhibited (MIC90s) ranging from...
Hata, K, Kimura, J, Miki, H, Toyosawa, T, Moriyama, M, Katsu, K
ER-30346 is a novel oral triazole with a broad spectrum of potent activity against a wide range of fungi. In the present study, we investigated the therapeutic effects of oral ER-30346 on...
Richie, E R, McEntire, B, Crispe, N, Kimura, J, Lanier, L L, Allison, J P
Alterations in gene expression that orchestrate eukaryotic cellular differentiation often require appropriate interactions between differentiating cells and a specialized microenvironment. During...
Havran, W L, Grell, S, Duwe, G, Kimura, J, Wilson, A, Kruisbeek, A M, ...
To study the origin of and the degree of T-cell antigen receptor (TCR) diversity of Thy-1+ dendritic epidermal cells (Thy-1+ dECs) in mice, we have developed a monoclonal antibody (mAb 536) to the...
Takahata, T, Tsuchida, S, Oomura, M, Matsumoto, T, Azumi, J, Hatayama, I, ...
Although the three-dimensional structure of human glutathione transferase (GST) P1-1 crystallized with a GSH analogue has been reported, its structure in the non-complexed form has not been...
Kimura, J, Hayakari, M, Kumano, T, Nakano, H, Satoh, K, Tsuchida, S
Since glutathione transferases (GSTs) are suggested to be involved in the prevention of tissue damage by oxidative stress, quantitative and qualitative alterations of GST forms were examined in rat...
Kumano, T, Kimura, J, Hayakari, M, Yamazaki, T, Sawamura, D, Tsuchida, S
Comparison of Hirosaki hairless rat (HHR) and Sprague-Dawley (SD) rat liver glutathione transferase (GST) subunits by HPLC revealed differences in subunit 3; a new peak was detected in HHR GSTs and...
Angiotensin II activation of a chloride current in rabbit cardiac myocytes.
Morita, H, Kimura, J, Endoh, M
1. The effects of angiotensin II (Ang II) on membrane currents were investigated in single ventricular myocytes from the rabbit heart by the whole-cell voltage-clamp method. 2. In the presence of an...
Identification of sodium-calcium exchange current in single ventricular cells of guinea-pig.
Kimura, J, Miyamae, S, Noma, A
1. The Na-Ca exchange current was investigated in single ventricular cells from guinea-pig hearts by combining the techniques of whole-cell voltage clamp and intracellular perfusion. 2. The membrane...
Cardiac musculature of the cranial vena cava in the common tree shrew (Tupaia glis).
Endo, H, Maeda, S, Kimura, J, Yamada, J, Rerkamnuaychoke, W, Chungsamarnyart, N, ...
Cardiac musculature of the cranial vena cava in the common tree shrew (Tupaia glis) was examined by light and transmission electron microscopy. The common tree shrew has well developed cardiac...
Kurohmaru, M, Maeda, S, Suda, A, Hondo, E, Ogawa, K, Endo, H, ...
The seminiferous epithelium of the common tree shrew (Tupaia glis) was investigated using transmission electron microscopy and lectin-histochemistry. It was compared with that of shrews examined in...
Hata, K, Kimura, J, Miki, H, Toyosawa, T, Nakamura, T, Katsu, K
ER-30346 is a novel oral triazole with a broad spectrum of potent activity against a wide range of fungi. ER-30346, with MICs at which 90% of the strains tested are inhibited (MIC90s) ranging from...
Hata, K, Kimura, J, Miki, H, Toyosawa, T, Moriyama, M, Katsu, K
ER-30346 is a novel oral triazole with a broad spectrum of potent activity against a wide range of fungi. In the present study, we investigated the therapeutic effects of oral ER-30346 on...
Richie, E R, McEntire, B, Crispe, N, Kimura, J, Lanier, L L, Allison, J P
Alterations in gene expression that orchestrate eukaryotic cellular differentiation often require appropriate interactions between differentiating cells and a specialized microenvironment. During...
Havran, W L, Grell, S, Duwe, G, Kimura, J, Wilson, A, Kruisbeek, A M, ...
To study the origin of and the degree of T-cell antigen receptor (TCR) diversity of Thy-1+ dendritic epidermal cells (Thy-1+ dECs) in mice, we have developed a monoclonal antibody (mAb 536) to the...
Angiotensin II activation of a chloride current in rabbit cardiac myocytes.
Morita, H, Kimura, J, Endoh, M
1. The effects of angiotensin II (Ang II) on membrane currents were investigated in single ventricular myocytes from the rabbit heart by the whole-cell voltage-clamp method. 2. In the presence of an...
Cardiac musculature of the cranial vena cava in the common tree shrew (Tupaia glis).
Endo, H, Maeda, S, Kimura, J, Yamada, J, Rerkamnuaychoke, W, Chungsamarnyart, N, ...
Cardiac musculature of the cranial vena cava in the common tree shrew (Tupaia glis) was examined by light and transmission electron microscopy. The common tree shrew has well developed cardiac...
Kurohmaru, M, Maeda, S, Suda, A, Hondo, E, Ogawa, K, Endo, H, ...
The seminiferous epithelium of the common tree shrew (Tupaia glis) was investigated using transmission electron microscopy and lectin-histochemistry. It was compared with that of shrews examined in...
Identification of sodium-calcium exchange current in single ventricular cells of guinea-pig.
Kimura, J, Miyamae, S, Noma, A
1. The Na-Ca exchange current was investigated in single ventricular cells from guinea-pig hearts by combining the techniques of whole-cell voltage clamp and intracellular perfusion. 2. The membrane...
Takahata, T, Tsuchida, S, Oomura, M, Matsumoto, T, Azumi, J, Hatayama, I, ...
Although the three-dimensional structure of human glutathione transferase (GST) P1-1 crystallized with a GSH analogue has been reported, its structure in the non-complexed form has not been...
Kimura, J, Hayakari, M, Kumano, T, Nakano, H, Satoh, K, Tsuchida, S
Since glutathione transferases (GSTs) are suggested to be involved in the prevention of tissue damage by oxidative stress, quantitative and qualitative alterations of GST forms were examined in rat...
Kumano, T, Kimura, J, Hayakari, M, Yamazaki, T, Sawamura, D, Tsuchida, S
Comparison of Hirosaki hairless rat (HHR) and Sprague-Dawley (SD) rat liver glutathione transferase (GST) subunits by HPLC revealed differences in subunit 3; a new peak was detected in HHR GSTs and...
Immunocytochemical characterization of glial fibrillary tangles in Alzheimer's disease brain.
Nishimura, M., Tomimoto, H., Suenaga, T., Namba, Y., Ikeda, K., Akiguchi, I., ...
Neurofibrillary tangle is a major cytoskeletal pathology in Alzheimer's disease brains, and has been considered to develop exclusively in neuronal cells. We examined brains with Alzheimer's disease...
Aberrant accumulation of phospholipase C-delta in Alzheimer brains.
Shimohama, S., Homma, Y., Suenaga, T., Fujimoto, S., Taniguchi, T., Araki, W., ...
Since phosphoinositide-specific phospholipase C (PLC) is one of the key molecules in signal transduction, the authors assessed its involvement in Alzheimer's disease (AD). Immunostaining of a...
Beta/A4 proteinlike immunoreactive granular structures in the brain of senescence-accelerated mouse.
Takemura, M., Nakamura, S., Akiguchi, I., Ueno, M., Oka, N., Ishikawa, S., ...
The immunohistochemical localization of amyloid beta/A4 protein in the senescence-accelerated mouse brain was studied using six different antisera against human amyloid precursor protein peptides....
Tomimoto, H., Akiguchi, I., Akiyama, H., Kimura, J., Yanagihara, T.
We report here on T-cell infiltration and diffuse expression of the major histocompatibility complex (MHC) class II antigen in a heterogeneous group of macrophages and microglia in...
Induction of brain tumors by a newly isolated JC virus (Tokyo-1 strain).
Nagashima, K., Yasui, K., Kimura, J., Washizu, M., Yamaguchi, K., Mori, W.
A newly isolated virus from a patient with progressive multifocal leukoencephalopathy (PML) (Tokyo-1 strain) was found serologically identical to JC virus (Mad-1 strain) and showed high...
Kimura, J, Takada, H, Nomura, A, Ohno, T, Mizuno, Y, Saito, M, ...
To clarify the functional state of T cells in Kawasaki disease, we analysed mRNA expression levels of Th1/Th2 cytokines (IFN-γ and IL-4) along with Th1/Th2-inducing transcription factors, T-bet and...
Watano, T., Kimura, J., Morita, T., Nakanishi, H.
1. The effects of No. 7943 on the Na+/Ca2+ exchange current and on other membrane currents were investigated in single cardiac ventricular cells of guinea-pig with the whole-cell voltage-clamp...
Yamauchi, H, Pagani, M, Fukuyama, H, Ouchi, Y, Nagahama, Y, Matsuzaki, S, ...
In cerebrovascular disease, progression of brain atrophy may reflect an increase in ischaemic changes. The purpose of this study was to determine whether atrophy of the corpus callosum progresses in...
Yamauchi, H, Fukuyama, H, Nagahama, Y, Nabatame, H, Nakamura, K, Yamamoto, Y, ...
OBJECTIVES--In major cerebral arterial occlusive diseases, patients with inadequate blood supply relative to metabolic demand (misery perfusion) may be at increased risk for cerebral ischaemia. This...
Refractory period of human motor nerve fibres.
Kimura, J, Yamada, T, Rodnitzky, R L
Using a collision technique, the ulnar nerve was made refractory for a shorter distance normally covered in 0.5 ms or a longer distance covered in 1.5 ms. Studying the shorter refractory segment with...
Hayashi, M, Isozaki, E, Oda, M, Tanabe, H, Kimura, J
OBJECTIVES: Vocal cord palsy seen in some patients with multiple system atrophy may result from neuronopathy of the recurrent laryngeal nerve. METHODS: Six controls and six patients with multiple...
Apolipoprotein E polymorphism in Japanese patients with Alzheimer's disease or vascular dementia.
Kawamata, J, Tanaka, S, Shimohama, S, Ueda, K, Kimura, J
Apolipoprotein E (ApoE) plays a key part in lipid metabolism both in the liver, and in the CNS. To clarify the association of ApoE polymorphism with Alzheimer's disease and vascular dementia in...
Mezaki, T, Kaji, R, Hamano, T, Nagamine, T, Shibasaki, H, Shimizu, T, ...
Twenty two patients with cervical and axial dystonias were treated with Japanese type A botulinum toxin. Injections were given repeatedly at intervals of 28-30 days to carefully chosen muscles with...
Terada, K, Ikeda, A, Van Ness, P C, Nagamine, T, Kaji, R, Kimura, J, ...
The method of jerk-locked back averaging was applied to six patients with clinically diagnosed psychogenic myoclonus. Five patients had a slow negative EEG shift corresponding to...
Tani, T, Yamamoto, H, Kimura, J
OBJECTIVES—To precisely localise the site of conduction block in elderly patients with cervical spondylotic myelopathy in the presence of multilevel compression shown by MRI. METHODS—A total of...
Mima, T., Ikeda, A., Nagamine, T., Yazawa, S., Kunieda, T., Mikuni, N., ...
OBJECTIVE—To investigate somesthetic functions of the perisylvian cortex. Methods—Somatosensory evoked magnetic fields (SEFs) and somatosensory evoked potentials (SEPs) of the perisylvian cortex...
Tachibana, N, Kimura, K, Kitajima, K, Shinde, A, Kimura, J, Shibasaki, H
Various neurodegenerative diseases involving brainstem structures as one of the main pathological lesions are reported to be associated with REM sleep behaviour disorder. Full blown REM sleep...
Wofsy, L., Baker, P. C., Thompson, K., Goodman, J., Kimura, J., Henry, C.
A hapten-sandwich procedure has been developed for specific labeling of cell surface antigens for fluorescence or electron microscopy. Haptens are azo-coupled to immunoglobulins specific for a cell...