J. Kosacka

Apolipoproteins D and E3 exert neurotrophic and synaptogenic effects in dorsal root ganglion cell cultures (2009)

Kosacka, J., Gericke, M., Nowicki, M., Kacza, J., Borlak, J., Spanel-Borowski, K.

Co-cultures of 3T3-L1 adipocytes with neurons from the rat dorsal root ganglia (DRG) showed enhanced neuritogenesis and synaptogenesis. Microarray analysis for upregulated genes in adipocyte/DRG...

Deferoxamine-induced neurite outgrowth and synapse formation in postnatal rat dorsal root ganglion (DRG) cell cultures (2009)

Nowicki, M., Kosacka, J., Spanel-Borowski, K., Borlak, J.

Deferoxamine (DFO) was granted orphan drug status for the treatment of traumatic spinal cord injury but its neuroprotective mechanism is not well understood. We therefore investigated the mode of...

The myelin-associated glycoprotein inhibitor BENZ induces outgrowth and survival of rat dorsal root ganglion cell cultures (2007)

Nowicki, M., Kosacka, J., Brossmer, R., Spanel-Borowski, K., Borlak, J.

The novel myelin-associated glycoprotein (MAG) inhibitor BENZ binds to the N-acetylneuraminic acid (Neu5Ac) portion of the N-terminal Ig-like domain of MAG. Treatment of rat dorsal root ganglion...

Adipocyte-derived angiopoietin-1 supports neurite outgrowth and synaptogenesis of sensory neurons (2006)

Kosacka, J., Nowicki, M., Kacza, J., Borlak, J., Engele, J., Spanel-Borowski, K.

Sensory and sympathetic innervation of the white fat tissue (WAT) contributes to lipolysis. In addition, both fiber types adapt in density to weight gain and loss. Because these findings are...