J. Lescar

Publication List Details

Period

1994 - 1999

Number

10

Co-Authors

Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

Chitarra, V, Alzari, P M, Bentley, G A, Bhat, T N, Eiselé, J L, Houdusse, A, ...

Although antibodies are highly specific, cross-reactions are frequently observed. To understand the molecular basis of this phenomenon, we studied the anti-hen egg lysozyme (HEL) monoclonal antibody...

Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase

Delarue, M., Boulé, J.B., Lescar, J., Expert-Bezançon, N., Jourdan, N., Sukumar, N., ...

The crystal structure of the catalytic core of murine terminal deoxynucleotidyltransferase (TdT) at 2.35 Å resolution reveals a typical DNA polymerase β-like fold locked in a closed form. In...

Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

Chitarra, V, Alzari, P M, Bentley, G A, Bhat, T N, Eiselé, J L, Houdusse, A, ...

Although antibodies are highly specific, cross-reactions are frequently observed. To understand the molecular basis of this phenomenon, we studied the anti-hen egg lysozyme (HEL) monoclonal antibody...

Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase

Delarue, M., Boulé, J.B., Lescar, J., Expert-Bezançon, N., Jourdan, N., Sukumar, N., ...

The crystal structure of the catalytic core of murine terminal deoxynucleotidyltransferase (TdT) at 2.35 Å resolution reveals a typical DNA polymerase β-like fold locked in a closed form. In...

Crystal structures of pheasant and guinea fowl egg-white lysozymes.

Lescar, J., Souchon, H., Alzari, P. M.

The crystal structures of pheasant and guinea fowl lysozymes have been determined by X-ray diffraction methods. Guinea fowl lysozyme crystallizes in space group P6(1)22 with cell dimensions a = 89.2...

Preliminary crystallographic studies of an anti-HIV-1 protease antibody that inhibits enzyme activity.

Lescar, J., Stouracova, R., Riottot, M. M., Chitarra, V., Brynda, J., Fabry, M., ...

F11.2.32, a monoclonal antibody directed against the HIV-1 protease, displays strong inhibitory effects toward the catalytic activity of the enzyme. The antibody cross-reacts with peptides 36-46 and...

Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.

Lescar, J., Brynda, J., Rezacova, P., Stouracova, R., Riottot, M. M., Chitarra, V., ...

The monoclonal antibody 1696, directed against the HIV-1 protease, displays strong inhibitory effects toward the catalytic activity of the enzyme of both the HIV-1 and HIV-2 isolates. This antibody...