DNA unwinding and inhibition of mouse leukemia L1210 DNA topoisomerase I by intercalators.
Pommier, Y, Covey, J M, Kerrigan, D, Markovits, J, Pham, R
The DNA unwinding effects of some 9-aminoacridine derivatives were compared under reaction conditions that could be used to study drug-induced topoisomerase II inhibition. An assay was designed to...
DNA unwinding and inhibition of mouse leukemia L1210 DNA topoisomerase I by intercalators.
Pommier, Y, Covey, J M, Kerrigan, D, Markovits, J, Pham, R
The DNA unwinding effects of some 9-aminoacridine derivatives were compared under reaction conditions that could be used to study drug-induced topoisomerase II inhibition. An assay was designed to...