J. M. Lemire

1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis.

Lemire, J M, Archer, D C

The hormone, 1,25-dihydroxyvitamin D3 (1,25-[OH]2-D3), inhibits lymphocyte activation in vitro. We studied the ability of the vitamin D metabolite to interfere in vivo with a primary T cell-mediated...

Acid phosphatase polypeptides in Saccharomyces cerevisiae are encoded by a differentially regulated multigene family.

Rogers, D T, Lemire, J M, Bostian, K A

Two clones from a lambda phage collection containing yeast genes regulated by inorganic phosphate were shown by low-stringency hybridization to select three mRNAs that direct the in vitro synthesis...

In vitro synthesis of repressible yeast acid phosphatase: identification of multiple mRNAs and products.

Bostian, K A, Lemire, J M, Cannon, L E, Halvorson, H O

Antibodies to repressible nonspecific acid phosphatase [APase; orthophosphoric-monoester phosphohydrolase (acid optimum), EC 3.1.3.2] purified from Saccharomyces cerevisiae were used to detect the in...

Regulation of repressible acid phosphatase gene transcription in Saccharomyces cerevisiae.

Lemire, J M, Willcocks, T, Halvorson, H O, Bostian, K A

We examined the genetic system responsible for transcriptional regulation of repressible acid phosphatase (APase; orthophosphoric-monoester phosphohydrolase [acid optimum, EC 3.1.3.2]) in...

Physiological control of repressible acid phosphatase gene transcripts in Saccharomyces cerevisiae.

Bostian, K A, Lemire, J M, Halvorson, H O

We have examined the regulation of repressible acid phosphatase (APase; orthophosphoric-monoester phosphohydrolase [acid optimum], EC 3.1.3.2) in Saccharomyces cerevisiae at the physiological and...

Synthesis of repressible acid phosphatase in Saccharomyces cerevisiae under conditions of enzyme instability.

Bostian, K A, Lemire, J M, Halvorson, H O

The synthesis of repressible acid phosphatase in Saccharomyces cerevisiae was examined under conditions of blocked derepression as described by Toh-e et al. (Mol. Gen. Genet. 162:139-149, 1978)....

1 alpha,25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells.

Lemire, J M, Adams, J S, Sakai, R, Jordan, S C

Activated B and T lymphocytes from normal human subjects are known to have the specific high-affinity receptor for 1,25-dihydroxyvitamin D3 (1,25-(OH)2-D3). In an attempt to determine a functional...

1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis.

Lemire, J M, Archer, D C

The hormone, 1,25-dihydroxyvitamin D3 (1,25-[OH]2-D3), inhibits lymphocyte activation in vitro. We studied the ability of the vitamin D metabolite to interfere in vivo with a primary T cell-mediated...

Acid phosphatase polypeptides in Saccharomyces cerevisiae are encoded by a differentially regulated multigene family.

Rogers, D T, Lemire, J M, Bostian, K A

Two clones from a lambda phage collection containing yeast genes regulated by inorganic phosphate were shown by low-stringency hybridization to select three mRNAs that direct the in vitro synthesis...

In vitro synthesis of repressible yeast acid phosphatase: identification of multiple mRNAs and products.

Bostian, K A, Lemire, J M, Cannon, L E, Halvorson, H O

Antibodies to repressible nonspecific acid phosphatase [APase; orthophosphoric-monoester phosphohydrolase (acid optimum), EC 3.1.3.2] purified from Saccharomyces cerevisiae were used to detect the in...

Regulation of repressible acid phosphatase gene transcription in Saccharomyces cerevisiae.

Lemire, J M, Willcocks, T, Halvorson, H O, Bostian, K A

We examined the genetic system responsible for transcriptional regulation of repressible acid phosphatase (APase; orthophosphoric-monoester phosphohydrolase [acid optimum, EC 3.1.3.2]) in...

Physiological control of repressible acid phosphatase gene transcripts in Saccharomyces cerevisiae.

Bostian, K A, Lemire, J M, Halvorson, H O

We have examined the regulation of repressible acid phosphatase (APase; orthophosphoric-monoester phosphohydrolase [acid optimum], EC 3.1.3.2) in Saccharomyces cerevisiae at the physiological and...

Synthesis of repressible acid phosphatase in Saccharomyces cerevisiae under conditions of enzyme instability.

Bostian, K A, Lemire, J M, Halvorson, H O

The synthesis of repressible acid phosphatase in Saccharomyces cerevisiae was examined under conditions of blocked derepression as described by Toh-e et al. (Mol. Gen. Genet. 162:139-149, 1978)....

1 alpha,25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells.

Lemire, J M, Adams, J S, Sakai, R, Jordan, S C

Activated B and T lymphocytes from normal human subjects are known to have the specific high-affinity receptor for 1,25-dihydroxyvitamin D3 (1,25-(OH)2-D3). In an attempt to determine a functional...

Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine.

Lemire, J. M., Shiojiri, N., Fausto, N.

Oval cells may function as facultative liver stem cells and tumor progenitors in liver carcinogenesis. The authors determined whether oval cells proliferate and if small hepatocytes might be...

Characterization of cloned aortic smooth muscle cells from young rats.

Lemire, J. M., Covin, C. W., White, S., Giachelli, C. M., Schwartz, S. M.

Clones were derived by dilute plating from cultured aortic smooth muscle cells of 12-day-old rats. Clones Pup I to III resemble uncloned smooth muscle cultures from aortas of rat pups and from adult...