J. M. Lundberg

Publication List Details

Period

1986 - 1995

Number

42

Co-Authors

Cardiac oufflow of endothelin, neuropeptide Y and noradrenaline in relation to hyperaemia in coronary sinus flow following electrical conversion of induced ventricular fibrillation in man (1995)

RUNSIÖ, M., ROSENQVIST, M., BERGFELDT, L., ÖWALL, A., LUNDBERG, J. M., FRANCO-CERECEDA, A.

The implanted cardioverter defibrillator represents an alternative therapy for patients with drug-refractory nialignant ventricular arrhythmios. Implantation and testing of the device requires that...

Cardiac oufflow of endothelin, neuropeptide Y and noradrenaline in relation to hyperaemia in coronary sinus flow following electrical conversion of induced ventricular fibrillation in man (1995)

RUNSIÖ, M., ROSENQVIST, M., BERGFELDT, L., ÖWALL, A., LUNDBERG, J. M., FRANCO-CERECEDA, A.

The implanted cardioverter defibrillator represents an alternative therapy for patients with drug-refractory nialignant ventricular arrhythmios. Implantation and testing of the device requires that...

Prognostic value of plasma neuropeptide-Y in coronary care unit patients with and without acute myocardial infarction (1994)

ULLMAN, B., HULTING, J., LUNDBERG, J. M.

Plasma neuropeptide Y-like immunoreactivity (NPY-LI) is elevated in patients with acute myocardial ischaemia and congestive heart failure (CHF) owing to increased activity of the sympathetic nervous...

Neuropeptide Y and noradrenaline in human uterus and myometrium during normal and pre-eclamptic pregnancy (1986)

Fried, G., Hökfelt, T., Lundberg, J.M., Terenius, L., Hamberger, L.

The myometrial levels of noradrenaline (NA) and neuropeptide V (NPY), a recently discovered neuropeptide that coexists with NA in many sympathetic nerves, have been measured by immunohistochemistry...

Detection of neuropeptide Y and its mRNA in megakaryocytes: enhanced levels in certain autoimmune mice.

Ericsson, A, Schalling, M, McIntyre, K R, Lundberg, J M, Larhammar, D, Seroogy, K, ...

Neuropeptide tyrosine (neuropeptide Y, NPY) is a potent vasoconstrictor with a wide distribution in the central and peripheral nervous systems. Here we show that high levels of rat NPY mRNA are also...

Calcitonin gene-related peptide is a stimulator of renin secretion.

Kurtz, A, Muff, R, Born, W, Lundberg, J M, Millberg, B I, Gnädinger, M P, ...

Calcitonin gene-related peptide (CGRP) was found to stimulate renin secretion in vivo in normal human volunteers. Moreover, CGRP stimulated the release of renin in vitro from isolated rat renal...

Vasoactive intestinal polypeptide and cholinergic mechanisms in cat nasal mucosa: studies on choline acetyltransferase and release of vasoactive intestinal polypeptide.

Lundberg, J M, Anggård, A, Emson, P, Fahrenkrug, J, Hökfelt, T

Quantitative immunohistochemical analysis of the sphenopalatine ganglion in normal cats revealed that virtually all ganglion cells (98.5%) were immunoreactive to vasoactive intestinal polypeptide...

Organizational principles in the peripheral sympathetic nervous system: Subdivision by coexisting peptides (somatostatin-, avian pancreatic polypeptide-, and vasoactive intestinal polypeptide-like immunoreactive materials

Lundberg, J. M., Hökfelt, T., Änggård, A., Terenius, L., Elde, R., Markey, K., ...

Sympathetic ganglia and some peripheral tissues of adult guinea pig and cat were analyzed by the indirect immunofluorescence technique with antisera to catecholamine-synthesizing enzymes and some...

Cellular and subcellular localization of protein I in the peripheral nervous system.

Fried, G, Nestler, E J, De Camilli, P, Stjärne, L, Olson, L, Lundberg, J M, ...

The cellular and subcellular distribution of protein I, a major brain phosphoprotein, has been studied in the peripheral nervous system. The levels of protein I in various peripheral nerves and...

Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility.

Lundberg, J M, Tatemoto, K, Terenius, L, Hellström, P M, Mutt, V, Hökfelt, T, ...

In immunohistochemical studies using antisera to peptide YY (PYY), a 36 amino acid polypeptide isolated from porcine duodenum, it was found that PYY-like immunoreactivity occurred mainly in endocrine...

Enkephalin- and somatostatin-like immunoreactivities in human adrenal medulla and pheochromocytoma.

Lundberg, J M, Hamberger, B, Schultzberg, M, Hökfelt, T, Granberg, P O, Efendić, S, ...

By using the Coons indirect immunofluorescence technique, enkephalin-like immunoreactivity with a granular localization was observed in human adrenal medullary gland cells and pheochromocytomas. In...

A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig

Lundberg, J. M., Saria, A., Brodin, E., Rosell, S., Folkers, K.

Electrical stimulation of the cervical vagus nerve in anesthetized guinea pigs induced a rapid increase in respiratory insufflation pressure, suggesting increased airway resistance. After intravenous...

Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary.

Tschopp, F A, Henke, H, Petermann, J B, Tobler, P H, Janzer, R, Hökfelt, T, ...

Binding sites for synthetic human 125I-labeled calcitonin gene-related peptide (125I-CGRP) have been demonstrated in membranes of the human nervous system. Binding was high in the cerebellar cortex...

Elevated plasma endothelin-1 concentrations are associated with the severity of illness in patients with sepsis.

Pittet, J F, Morel, D R, Hemsen, A, Gunning, K, Lacroix, J S, Suter, P M, ...

Plasma immunoreactive endothelin-1 concentrations were determined by radioimmunoassay in 11 septic patients during the first 24 hours after the development of the sepsis syndrome in 15 nonseptic...

Autonomic mechanisms underlying capsaicin induced oral sensations and salivation in man.

Dunér-Engström, M, Fredholm, B B, Larsson, O, Lundberg, J M, Saria, A

The effects of capsaicin, citric acid and nicotine applied to the apex or radix of the tongue on taste sensations and salivation were studied in relation to the presence of substance P immunoreactive...

Detection of neuropeptide Y and its mRNA in megakaryocytes: enhanced levels in certain autoimmune mice.

Ericsson, A, Schalling, M, McIntyre, K R, Lundberg, J M, Larhammar, D, Seroogy, K, ...

Neuropeptide tyrosine (neuropeptide Y, NPY) is a potent vasoconstrictor with a wide distribution in the central and peripheral nervous systems. Here we show that high levels of rat NPY mRNA are also...

Calcitonin gene-related peptide is a stimulator of renin secretion.

Kurtz, A, Muff, R, Born, W, Lundberg, J M, Millberg, B I, Gnädinger, M P, ...

Calcitonin gene-related peptide (CGRP) was found to stimulate renin secretion in vivo in normal human volunteers. Moreover, CGRP stimulated the release of renin in vitro from isolated rat renal...

Vasoactive intestinal polypeptide and cholinergic mechanisms in cat nasal mucosa: studies on choline acetyltransferase and release of vasoactive intestinal polypeptide.

Lundberg, J M, Anggård, A, Emson, P, Fahrenkrug, J, Hökfelt, T

Quantitative immunohistochemical analysis of the sphenopalatine ganglion in normal cats revealed that virtually all ganglion cells (98.5%) were immunoreactive to vasoactive intestinal polypeptide...

Organizational principles in the peripheral sympathetic nervous system: Subdivision by coexisting peptides (somatostatin-, avian pancreatic polypeptide-, and vasoactive intestinal polypeptide-like immunoreactive materials

Lundberg, J. M., Hökfelt, T., Änggård, A., Terenius, L., Elde, R., Markey, K., ...

Sympathetic ganglia and some peripheral tissues of adult guinea pig and cat were analyzed by the indirect immunofluorescence technique with antisera to catecholamine-synthesizing enzymes and some...

Cellular and subcellular localization of protein I in the peripheral nervous system.

Fried, G, Nestler, E J, De Camilli, P, Stjärne, L, Olson, L, Lundberg, J M, ...

The cellular and subcellular distribution of protein I, a major brain phosphoprotein, has been studied in the peripheral nervous system. The levels of protein I in various peripheral nerves and...

Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility.

Lundberg, J M, Tatemoto, K, Terenius, L, Hellström, P M, Mutt, V, Hökfelt, T, ...

In immunohistochemical studies using antisera to peptide YY (PYY), a 36 amino acid polypeptide isolated from porcine duodenum, it was found that PYY-like immunoreactivity occurred mainly in endocrine...

Enkephalin- and somatostatin-like immunoreactivities in human adrenal medulla and pheochromocytoma.

Lundberg, J M, Hamberger, B, Schultzberg, M, Hökfelt, T, Granberg, P O, Efendić, S, ...

By using the Coons indirect immunofluorescence technique, enkephalin-like immunoreactivity with a granular localization was observed in human adrenal medullary gland cells and pheochromocytomas. In...

A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig

Lundberg, J. M., Saria, A., Brodin, E., Rosell, S., Folkers, K.

Electrical stimulation of the cervical vagus nerve in anesthetized guinea pigs induced a rapid increase in respiratory insufflation pressure, suggesting increased airway resistance. After intravenous...

Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary.

Tschopp, F A, Henke, H, Petermann, J B, Tobler, P H, Janzer, R, Hökfelt, T, ...

Binding sites for synthetic human 125I-labeled calcitonin gene-related peptide (125I-CGRP) have been demonstrated in membranes of the human nervous system. Binding was high in the cerebellar cortex...

Autonomic mechanisms underlying capsaicin induced oral sensations and salivation in man.

Dunér-Engström, M, Fredholm, B B, Larsson, O, Lundberg, J M, Saria, A

The effects of capsaicin, citric acid and nicotine applied to the apex or radix of the tongue on taste sensations and salivation were studied in relation to the presence of substance P immunoreactive...

Elevated plasma endothelin-1 concentrations are associated with the severity of illness in patients with sepsis.

Pittet, J F, Morel, D R, Hemsen, A, Gunning, K, Lacroix, J S, Suter, P M, ...

Plasma immunoreactive endothelin-1 concentrations were determined by radioimmunoassay in 11 septic patients during the first 24 hours after the development of the sepsis syndrome in 15 nonseptic...

Intragastric nitric oxide production in humans: measurements in expelled air.

Lundberg, J O, Weitzberg, E, Lundberg, J M, Alving, K

High values (800-6000 parts per billion) of nitric oxide (NO) in expelled air from the stomach were shown in humans by chemiluminescence technique. These NO values were more than 100 times higher...

Cardiac neuropeptide Y and noradrenaline balance in patients with congestive heart failure.

Feng, Q. P., Hedner, T., Andersson, B., Lundberg, J. M., Waagstein, F.

OBJECTIVE--To measure plasma concentrations of noradrenaline and neuropeptide Y-like immunoreactivity in relation to cardiac function in patients with congestive heart failure. DESIGN--Retrospective...

Neuropeptide Y and reserpine-resistant vasoconstriction evoked by sympathetic nerve stimulation in the dog skeletal muscle.

Pernow, J., Kahan, T., Lundberg, J. M.

1. The effects of sympathetic nerve stimulation (evoked by recordings of authentic irregular vasoconstrictor nerve fibre discharge with average frequencies of 0.59, 2.0 and 6.9 Hz) on the perfusion...

Noradrenaline release evoked by a physiological irregular sympathetic discharge pattern is modulated by prejunctional alpha- and beta-adrenoceptors in vivo.

Kahan, T., Pernow, J., Schwieler, J., Wallin, B. G., Lundberg, J. M., Hjemdahl, P.

1. Sympathetic nerve stimulation-evoked overflow of endogenous noradrenaline (NA) and vasoconstriction were studied in canine blood-perfused gracilis muscle in situ. Nerves were stimulated at an...

Capsaicin and nicotine-sensitive afferent neurones and nasal secretion in healthy human volunteers and in patients with vasomotor rhinitis.

Stjärne, P., Lundblad, L., Lundberg, J. M., Anggård, A.

1. Applications of capsaicin, nicotine and methacholine were made locally onto the nasal mucosa in human controls and patients suffering from hyperreactive nasal disorders. Perception of sensation...

Evidence for co-transmitter role of neuropeptide Y in the pig spleen.

Lundberg, J. M., Rudehill, A., Sollevi, A., Hamberger, B.

1. The possible involvement of neuropeptide Y (NPY) in relation to noradrenaline (NA) and adenosine triphosphate (ATP) mechanisms in the sympathetic nervous control of the vascular tone and capsule...

Sympathetic vascular control of the pig nasal mucosa: adrenoceptor mechanisms in blood flow and volume control.

Lacroix, J. S., Lundberg, J. M.

1. The adrenoceptor mechanisms influencing the total blood flow, volume and superficial blood flow in the nasal mucosa of pigs anaesthetized with pentobarbitone have been characterized by use of...

Effect of nedocromil sodium on allergen-, PAF-, histamine- and bradykinin-induced airways vasodilatation and pulmonary obstruction in the pig.

Alving, K., Matran, R., Lundberg, J. M.

1. The influence of nedocromil sodium on the nasal and bronchial effects induced by allergen, platelet-activating factor (PAF), capsaicin, histamine and bradykinin aerosol challenge in...

Ruthenium-red inhibits CGRP release by capsaicin and resiniferatoxin but not by ouabain, bradykinin or nicotine in guinea-pig heart: correlation with effects on cardiac contractility.

Franco-Cereceda, A., Lou, Y. P., Lundberg, J. M.

1. The possible influence of ruthenium-red (RR) on contractility and outflow of calcitonin gene-related peptide (CGRP)-like and neuropeptide Y (NPY)-like immunoreactivity (LI) from the heart of the...

Inhibition of sympathetic vasoconstriction in pigs in vivo by the neuropeptide Y-Y1 receptor antagonist BIBP 3226.

Lundberg, J. M., Modin, A.

1. Recently, a potent non-peptide antagonist of neuropeptide Y (NPY)-Y1 receptors has been developed. In this study, the selectivity of this compound, BIBP 3226, as a functional Y1 receptor...

Effects of local and systemic budesonide on allergen-induced airway reactions in the pig.

Fornhem, C., Dahlbäck, M., Kumlin, M., Lundberg, J. M., Alving, K.

1. In this study, an attempt was made to distinguish between local and systemic effects of low doses of the topical glucocorticoid, budesonide. The effect of aerosolized budesonide administered to...

Bosentan-improved cardiopulmonary vascular performance and increased plasma levels of endothelin-1 in porcine endotoxin shock.

Weitzberg, E., Hemsén, A., Rudehill, A., Modin, A., Wanecek, M., Lundberg, J. M.

1. To evaluate the possible contribution of endothelin-1 (ET-1) to the pathophysiology of porcine septic shock, the non-peptide, mixed ET-receptor antagonist, bosentan (RO 47-0203) was administered...

Cigarette smoke, nicotine and capsaicin aerosol-induced vasodilatation in pig respiratory mucosa.

Matran, R., Alving, K., Lundberg, J. M.

1. Anesthetized pigs were used to study vascular responses in the sphenopalatine artery (SPA), superior laryngeal artery (SLA) and bronchial artery (BA) upon exposure to cigarette smoke or aerosol of...

Postjunctional inhibitory effect of the NK2 receptor antagonist, SR 48968, on sensory NANC bronchoconstriction in the guinea-pig.

Lou, Y. P., Lee, L. Y., Satoh, H., Lundberg, J. M.

1 The effects of a selective NK2 receptor antagonist, SR 48968, on non-adrenergic non-cholinergic (NANC) bronchoconstriction in the guinea-pig were investigated in both in vitro and in vivo studies....

Pulmonary effects of endogenous and exogenous nitric oxide in the pig: relation to cigarette smoke inhalation.

Alving, K., Fornhem, C., Lundberg, J. M.

1. Pentobarbitone-anaesthetized pigs were challenged with cigarette smoke (unfiltered or filtered through a Cambridge glass fibre filter to remove the particulate phase including nicotine), as well...