Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells.
Bojanowski, K, Lelievre, S, Markovits, J, Couprie, J, Jacquemin-Sablon, A, Larsen, A K
The antitrypanosomal and antifiliarial drug suramin is currently under investigation for treatment of advanced malignancies including prostatic cancer, adrenocortical cancer, and some lymphomas and...
Jacob, L, Viard, J P, Allenet, B, Anin, M F, Slama, F B, Vandekerckhove, J, ...
A crude supernatant of hybridoma secreting a monoclonal anti-double-stranded (ds)DNA antibody (PME77 mAb), used to stain fibroblasts (CVI cells) in immunofluorescence, gives a punctuated staining of...
DNA unwinding and inhibition of mouse leukemia L1210 DNA topoisomerase I by intercalators.
Pommier, Y, Covey, J M, Kerrigan, D, Markovits, J, Pham, R
The DNA unwinding effects of some 9-aminoacridine derivatives were compared under reaction conditions that could be used to study drug-induced topoisomerase II inhibition. An assay was designed to...
Markovits, J, Ramstein, J, Roques, B P, Le Pecq, J B
Ethidium dimer is shown to bind by intercalation, almost equally well, to the B and Z form of poly[(dG-m5dC)].poly[(dG-m5dC)], whereas the ethidium monomer shows a strong preference for the B form....
Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells.
Bojanowski, K, Lelievre, S, Markovits, J, Couprie, J, Jacquemin-Sablon, A, Larsen, A K
The antitrypanosomal and antifiliarial drug suramin is currently under investigation for treatment of advanced malignancies including prostatic cancer, adrenocortical cancer, and some lymphomas and...
Jacob, L, Viard, J P, Allenet, B, Anin, M F, Slama, F B, Vandekerckhove, J, ...
A crude supernatant of hybridoma secreting a monoclonal anti-double-stranded (ds)DNA antibody (PME77 mAb), used to stain fibroblasts (CVI cells) in immunofluorescence, gives a punctuated staining of...
DNA unwinding and inhibition of mouse leukemia L1210 DNA topoisomerase I by intercalators.
Pommier, Y, Covey, J M, Kerrigan, D, Markovits, J, Pham, R
The DNA unwinding effects of some 9-aminoacridine derivatives were compared under reaction conditions that could be used to study drug-induced topoisomerase II inhibition. An assay was designed to...
Markovits, J, Ramstein, J, Roques, B P, Le Pecq, J B
Ethidium dimer is shown to bind by intercalation, almost equally well, to the B and Z form of poly[(dG-m5dC)].poly[(dG-m5dC)], whereas the ethidium monomer shows a strong preference for the B form....