J. Menard

Publication List Details

Period

1991 - 2003

Number

41

Co-Authors

Double-layer-relevant laboratory results (1992)

Diebold, D., Forest, C.E., Hershkowitz, Noah, Intrator, T., Kaufman, D., ...

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Molecular cloning of genes encoding branched-chain keto acid dehydrogenase of Pseudomonas putida.

Sykes, P J, Burns, G, Menard, J, Hatter, K, Sokatch, J R

We cloned the structural genes for the individual subunits of the branched-chain keto acid dehydrogenase multienzyme complex on a 7.8-kilobase EcoRI-SstI restriction fragment of Pseudomonas putida...

Conjugative mapping of pyruvate, 2-ketoglutarate, and branched-chain keto acid dehydrogenase genes in Pseudomonas putida mutants.

Sykes, P J, Menard, J, McCully, V, Sokatch, J R

Branched-chain keto acid dehydrogenase, an enzyme in the common pathway of branched-chain amino acid catabolism of Pseudomonas putida, is a multienzyme complex which catalyzes the oxidative...

Response of plasma prorenin and active renin to chronic and acute alterations of renin secretion in normal humans. Studies using a direct immunoradiometric assay.

Toffelmire, E B, Slater, K, Corvol, P, Menard, J, Schambelan, M

We employed a novel immunoradiometric assay to measure plasma levels of active renin and prorenin in physiologic and pharmacologic studies designed to characterize renin biosynthesis and processing...

Synthesis of peptides related to the prosegment of mouse submaxillary gland renin precursor: an approach to renin inhibitors.

Evin, G, Devin, J, Castro, B, Menard, J, Corvol, P

The complete sequence of the structural gene coding for mouse submaxillary gland renin was recently reported and the amino acid sequence of preprorenin was deduced. This sequence includes a 45-amino...

Isolation of renin-producing human cells by transfection with three simian virus 40 mutants.

Pinet, F, Corvol, M T, Dench, F, Bourguignon, J, Feunteun, J, Menard, J, ...

A human juxtaglomerular cell (JGC) tumor was used for the immortalization of renin-secreting cells. The transfection of primary JGC with three different simian virus 40 (SV40) mutants resulted in the...

Renin biosynthesis by human tumoral juxtaglomerular cells. Evidences for a renin precursor.

Galen, F X, Devaux, C, Houot, A M, Menard, J, Corvol, P, Corvol, M T, ...

Renin biosynthesis was studied in a juxtaglomerular cell tumor. The tumoral tissue had a high renin content (180 Goldblatt Units/g of tissue), was heavily stained by immunofluorescence using human...

New monoclonal antibodies directed against human renin. Powerful tools for the investigation of the renin system.

Galen, F X, Devaux, C, Atlas, S, Guyenne, T, Menard, J, Corvol, P, ...

Monoclonal antibodies directed against human renin were obtained by the fusing of myeloma cells with spleen cells from Balb/c or high-responder Biozzi mice injected with pure tumoral or highly...

Characterization of precursor and secreted forms of human angiotensinogen.

Campbell, D J, Bouhnik, J, Coezy, E, Menard, J, Corvol, P

To define the basis of the heterogeneity of angiotensinogen, we have characterized the immunoreactivity of high molecular weight (HMW) and low molecular weight (LMW) plasma angiotensinogen, the...

Regulation of prorenin secretion in cultured human transfected juxtaglomerular cells.

Pinet, F, Mizrahi, J, Laboulandine, I, Menard, J, Corvol, P

The regulation of renin secretion was studied in continuous culture of human juxtaglomerular cells (JGC), which provided a permanent source of human renin production (Pinet, F., M. T. Corvol, F....

New renin inhibitors homologous with pepstatin.

Eid, M, Evin, G, Castro, B, Menard, J, Corvol, P

Four homologues of pepstatin, the potent but poorly soluble inhibitor of aspartic proteinases, were synthesized by coupling to the C-terminus of the natural pentapeptide the following amino acid...

Biochemical tests for diagnosis of phaeochromocytoma: urinary versus plasma determinations.

Plouin, P F, Duclos, J M, Menard, J, Comoy, E, Bohuon, C, Alexandre, J M

Fifteen patients with hypertension due to phaeochromocytoma and 35 controls with essential hypertension were studied to assess the diagnostic value of urinary and plasma biochemical determinations in...

Factors predictive of attendance at clinic and blood pressure control in hypertensive patients.

Degoulet, P, Menard, J, Vu, H A, Golmard, J L, Devries, C, Chatellier, G, ...

Poor compliance with appointments and drug treatment is one of the recognised factors preventing effective management of hypertension. Factors predictive of poor attendance and inadequate blood...

Molecular cloning of genes encoding branched-chain keto acid dehydrogenase of Pseudomonas putida.

Sykes, P J, Burns, G, Menard, J, Hatter, K, Sokatch, J R

We cloned the structural genes for the individual subunits of the branched-chain keto acid dehydrogenase multienzyme complex on a 7.8-kilobase EcoRI-SstI restriction fragment of Pseudomonas putida...

Conjugative mapping of pyruvate, 2-ketoglutarate, and branched-chain keto acid dehydrogenase genes in Pseudomonas putida mutants.

Sykes, P J, Menard, J, McCully, V, Sokatch, J R

Branched-chain keto acid dehydrogenase, an enzyme in the common pathway of branched-chain amino acid catabolism of Pseudomonas putida, is a multienzyme complex which catalyzes the oxidative...

Response of plasma prorenin and active renin to chronic and acute alterations of renin secretion in normal humans. Studies using a direct immunoradiometric assay.

Toffelmire, E B, Slater, K, Corvol, P, Menard, J, Schambelan, M

We employed a novel immunoradiometric assay to measure plasma levels of active renin and prorenin in physiologic and pharmacologic studies designed to characterize renin biosynthesis and processing...

Synthesis of peptides related to the prosegment of mouse submaxillary gland renin precursor: an approach to renin inhibitors.

Evin, G, Devin, J, Castro, B, Menard, J, Corvol, P

The complete sequence of the structural gene coding for mouse submaxillary gland renin was recently reported and the amino acid sequence of preprorenin was deduced. This sequence includes a 45-amino...

Isolation of renin-producing human cells by transfection with three simian virus 40 mutants.

Pinet, F, Corvol, M T, Dench, F, Bourguignon, J, Feunteun, J, Menard, J, ...

A human juxtaglomerular cell (JGC) tumor was used for the immortalization of renin-secreting cells. The transfection of primary JGC with three different simian virus 40 (SV40) mutants resulted in the...

Renin biosynthesis by human tumoral juxtaglomerular cells. Evidences for a renin precursor.

Galen, F X, Devaux, C, Houot, A M, Menard, J, Corvol, P, Corvol, M T, ...

Renin biosynthesis was studied in a juxtaglomerular cell tumor. The tumoral tissue had a high renin content (180 Goldblatt Units/g of tissue), was heavily stained by immunofluorescence using human...

New monoclonal antibodies directed against human renin. Powerful tools for the investigation of the renin system.

Galen, F X, Devaux, C, Atlas, S, Guyenne, T, Menard, J, Corvol, P, ...

Monoclonal antibodies directed against human renin were obtained by the fusing of myeloma cells with spleen cells from Balb/c or high-responder Biozzi mice injected with pure tumoral or highly...

Characterization of precursor and secreted forms of human angiotensinogen.

Campbell, D J, Bouhnik, J, Coezy, E, Menard, J, Corvol, P

To define the basis of the heterogeneity of angiotensinogen, we have characterized the immunoreactivity of high molecular weight (HMW) and low molecular weight (LMW) plasma angiotensinogen, the...

Regulation of prorenin secretion in cultured human transfected juxtaglomerular cells.

Pinet, F, Mizrahi, J, Laboulandine, I, Menard, J, Corvol, P

The regulation of renin secretion was studied in continuous culture of human juxtaglomerular cells (JGC), which provided a permanent source of human renin production (Pinet, F., M. T. Corvol, F....

New renin inhibitors homologous with pepstatin.

Eid, M, Evin, G, Castro, B, Menard, J, Corvol, P

Four homologues of pepstatin, the potent but poorly soluble inhibitor of aspartic proteinases, were synthesized by coupling to the C-terminus of the natural pentapeptide the following amino acid...

Biochemical tests for diagnosis of phaeochromocytoma: urinary versus plasma determinations.

Plouin, P F, Duclos, J M, Menard, J, Comoy, E, Bohuon, C, Alexandre, J M

Fifteen patients with hypertension due to phaeochromocytoma and 35 controls with essential hypertension were studied to assess the diagnostic value of urinary and plasma biochemical determinations in...

Factors predictive of attendance at clinic and blood pressure control in hypertensive patients.

Degoulet, P, Menard, J, Vu, H A, Golmard, J L, Devries, C, Chatellier, G, ...

Poor compliance with appointments and drug treatment is one of the recognised factors preventing effective management of hypertension. Factors predictive of poor attendance and inadequate blood...

Sexual dimorphism in the osteoarthritis of STR/ort mice may be linked to articular cytokines

Mahr, S, Menard, J, Krenn, V, Muller, B

Objective: To analyse the early changes leading to OA by examining the articular cytokine expression and degenerative changes in STR/ort mice.

Prevention of diabetic nephropathy with enalapril in normotensive diabetics with microalbuminuria.

Marre, M., Chatellier, G., Leblanc, H., Guyene, T. T., Menard, J., Passa, P.

STUDY OBJECTIVE--To assess the effectiveness of inhibition of angiotensin converting enzyme in preventing diabetic nephropathy. DESIGN--Randomised follow up study of normotensive diabetics with...

Neurogenic hypertension associated with an excessively high excretion rate of catecholamine metabolites.

Funck-Brentano, C, Pagny, J Y, Menard, J

A 60 year old hypertensive patient suffered several cerebral infarctions. A phaeochromocytoma was suspected because the excretion rates of vanillylmandelic acid and its methoxy derivatives were...

Pharmacological investigations of a new renin inhibitor in normal sodium-unrestricted volunteers.

De Gasparo, M, Cumin, F, Nussberger, J, Guyenne, T T, Wood, J M, Menard, J

1. CGP 38 560 A, a low-molecular-weight, non-peptidic renin inhibitor, was well tolerated upon intravenous and oral administration to recumbent healthy volunteers on an unrestricted-sodium diet. 2....

Converting-enzyme inhibition buffers the counter-regulatory response to acute administration of nicardipine.

Bellet, M, Sassano, P, Guyenne, T, Corvol, P, Menard, J

1. To investigate the interaction of angiotensin-converting-enzyme (ACE) inhibitor and calcium antagonist, we conducted a double-blind randomized, placebo-controlled crossover study of a new ACE...

Antihypertensive effect of diacetolol in essential hypertension.

Thibonnier, M, Flabeau, C, Thouvenin, M, Roux, A, Flouvat, B, Pasquier, P, ...

1 Diacetolol is the N-acetylated metabolite of acebutolol and possesses beta-adrenergic receptor blocking properties. 2 Its antihypertensive action was assessed in accordance with a double-blind...

Sudden unexpected infant death in a French county.

Wagner, M, Samson-Dollfus, D, Menard, J

We report a study of sudden unexpected infant death (SUID) in a French county (Seine-Maritime) between 1978 and 1981 (rate of 2.71 per 1000 live births). The results agree with those of previous...

The number needed to treat: a clinically useful nomogram in its proper context.

Chatellier, G., Zapletal, E., Lemaitre, D., Menard, J., Degoulet, P.

The number needed to treat is a meaningful way of expressing the benefit of an active treatment over a control. It can be used either for summarising the results of a therapeutic trial or for medical...