Lin, Jennifer, Cook, Nancy R., Albert, Christine, Zaharris, Elaine, Gaziano, J. Michael, Van Denburgh, Martin, ...
Background Observational studies suggested that a diet high in fruits and vegetables, both of which are rich with antioxidants, may prevent cancer development. However, findings from randomized...
Ahn, Jiyoung, Schumacher, Fredrick R., Berndt, Sonja I., Pfeiffer, Ruth, Albanes, Demetrius, Andriole, Gerald L., ...
Twin studies suggest a heritable component to circulating sex steroid hormones and sex hormone-binding globulin (SHBG). In the NCI-Breast and Prostate Cancer Cohort Consortium, 874 SNPs in 37...
Normal systolic blood pressure and risk of heart failure in US male physicians (2009)
Britton, Kathryn A., Gaziano, J. Michael, Djoussé, Luc
Aims Heart failure (HF) is a major public health issue and hypertension is a major predictor of HF. Observational studies have demonstrated a continuous and graded relationship between ‘normal’...
Blood pressure measures and risk of chronic kidney disease in men (2008)
Schaeffner, Elke S., Kurth, Tobias, Bowman, Thomas S., Gelber, Rebecca P., Gaziano, J. Michael
Background. High blood pressure (BP) has been associated with a decrease in kidney function. However, it remains unclear which BP measure best predicts impaired kidney function. Methods. We compared...
The Association Between Statins and Cancer Incidence in a Veterans Population (2008)
Farwell, Wildon R., Scranton, Richard E., Lawler, Elizabeth V., Lew, Robert A., Brophy, Mary T., Fiore, Louis D., ...
Background Meta-analyses of trials of 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors or statins for cardiovascular disease prevention have failed to show any statistically significant benefit...
Scranton, Richard E, Gaziano, J Michael, Rutty, Dean, Ezrokhi, Michael, Cincotta, Anthony
Abstract Background Cycloset™ is a quick-release formulation of bromocriptine mesylate, a dopamine agonist, which in animal models of insulin resistance and type 2 diabetes acts centrally to reduce...
Haojie Li, Meir J. Stampfer, Lorelei A. Mucci, J. Michael Gaziano, David Hunter, ...
BackgroundVitamin D insufficiency is a common public health problem nationwide. Circulating 25-hydroxyvitamin D3 (25[OH]D), the most commonly used index of vitamin D status, is converted to the...
Plasma Lycopene, Other Carotenoids, and the Risk of Type 2 Diabetes in Women (2006)
Wang, Lu, Liu, Simin, Pradhan, Aruna D., Manson, JoAnn E., Buring, Julie E., Gaziano, J. Michael, ...
The authors conducted a nested case-control study from 1992 to 2003 among US women aged 45 years or older and free from cardiovascular disease and cancer to examine the prospective association among...
Kurth, Tobias, Walker, Alexander M., Glynn, Robert J., Chan, K. Arnold, Gaziano, J. Michael, Berger, Klaus, ...
Observational studies often provide the only available information about treatment effects. Control of confounding, however, remains challenging. The authors compared five methods for evaluating the...
Kurth, Tobias, Walker, Alexander M., Glynn, Robert J., Chan, K. Arnold, Gaziano, J. Michael, Berger, Klaus, ...
Observational studies often provide the only available information about treatment effects. Control of confounding, however, remains challenging. The authors compared five methods for evaluating the...
Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT) (2005)
Lippman, Scott M., Goodman, Phyllis J., Klein, Eric A., Parnes, Howard L., Thompson, Ian M., Kristal, Alan R., ...
Prostate cancer continues to be a major health threat, especially among African American men. The Selenium and Vitamin E Cancer Prevention Trial (SELECT), which opened on July 25, 2001, was planned...
Kurth, Tobias, Walker, Alexander M., Glynn, Robert J., Chan, K. Arnold, Gaziano, J. Michael, Berger, Klaus, ...
Observational studies often provide the only available information about treatment effects. Control of confounding, however, remains challenging. The authors compared five methods for evaluating the...
Coffey, Christopher S, Hebert, Patricia R, Ritchie, Marylyn D, Krumholz, Harlan M, Gaziano, J Michael, Ridker, Paul M, ...
Abstract Background To examine interactions among the angiotensin converting enzyme ( ACE ) insertion/deletion, plasminogen activator inhibitor-1 ( PAI-1 ) 4G/5G , and tissue plasminogen activator (...
Alcohol consumption and cardiovascular disease mortality in hypertensive men (2004)
Malinski, Maciej K, Sesso, Howard D, Lopez-Jimenez, Francisco, Buring, Julie E, Gaziano, J Michael
BACKGROUND: Heavy alcohol drinking is associated with a dose-dependent increase in blood pressure, but data on the relation between alcohol consumption and mortality in hypertensive patients are...
Heckbert, Susan R., Kooperberg, Charles, Safford, Monika M., Psaty, Bruce M., Hsia, Judith, McTiernan, Anne, ...
Limited information is available from large clinical investigations about the agreement among sources of diagnoses for endpoints. The authors used data from the Women’s Health Initiative clinical...
A Prospective Study of Plasma Selenium Levels and Prostate Cancer Risk (2004)
Li, Haojie, Stampfer, Meir J., Giovannucci, Edward L., Morris, J. Steven, Willett, Walter C., Gaziano, J. Michael, ...
Background: Epidemiologic studies suggest that low selenium levels are associated with an increased incidence of prostate cancer, although results are conflicting. We examined the association between...
A Prospective Study of Plasma C-Peptide and Colorectal Cancer Risk in Men (2004)
Ma, Jing, Giovannucci, Edward, Pollak, Michael, Leavitt, Azita, Tao, Yuzhen, Gaziano, J. Michael, ...
Background: Colorectal cancer and type 2 diabetes share many risk factors, and hyperinsulinemia appears to be associated with an increased risk of colorectal cancer. We used the concentration of...
Chan, June M., Stampfer, Meir J., Ma, Jing, Gann, Peter, Gaziano, J. Michael, Pollak, Michael, ...
Background: Plasma levels of insulin-like growth factor-I (IGF-I) have been associated with the risk of prostate cancer. However, the association of IGF-I with specific tumor stage and grade at...
Time urgency and risk of non-fatal myocardial infarction (2001)
Cole, Stephen R, Kawachi, Ichiro, Liu, Simin, Gaziano, J Michael, Manson, JoAnn E, Buring, Julie E, ...
Background Inconsistencies in the literature linking Type A behaviour pattern (TAB) to coronary heart disease (CHD) may be due to differences in the effects of various components of TAB, namely...
Ma, Jing, Giovannucci, Edward, Pollak, Michael, Chan, June M., Gaziano, J. Michael, Willett, Walter, ...
Background: Milk and dietary calcium may have antiproliferative effects against colorectal cancer, but milk intake also raises serum levels of insulin-like growth factor-I (IGF-I). A high ratio of...
US Department of Veterans Affairs Medical Care System as a Resource to Epidemiologists (2000)
Boyko, Edward J., Koepsell, Thomas D., Gaziano, J. Michael, Horner, Ronnie D., Feussner, John R.
Epidemiologists have utilized several health care systems with large numbers of enrollees and centralized databases to achieve their research aims. Although containing many of the features that have...
Field, Terry S., Gurwitz, Jerry H., Glynn, Robert J., Salive, Marcel E., Gaziano, J. Michael, Taylor, James O., ...
OBJECTIVE: To determine whether older people who use nonsteroidal anti-inflammatory agents (NSAIDs) have increased levels of blood urea nitrogen (BUN), serum creatinine, and BUN:serum creatinine...
Coffee and Tea Intake and the Risk of Myocardial Infarction (1999)
Sesso, Howard D., Gaziano, J. Michael, Buring, Julie E., Hennekens, Charles H.
The authors investigated the association of caffeinated coffee, decaffeinated coffee, and tea with myocardial infarction in a study of 340 cases and age-, sex-, and community-matched controls. The...
Verhoef, Petra, Stampfer, Meir J., Buring, Julie F., Gaziano, J. Michael, Allen, Robert H., Stabler, Sally P., ...
Elevated plasma homocyst(e)ine levels are an independent risk factor for vascular disease. In a case-control study, the authors studied the associations of fasting plasma homocyst(e)ine and vitamins,...
Coffey, Christopher S, Hebert, Patricia R, Ritchie, Marylyn D, Krumholz, Harlan M, Gaziano, J Michael, Ridker, Paul M, ...
Psychiatric Disease and Hypercholesterolemia in an Urban Academic Primary Care Clinic
Kaplowitz, Rebekah A., Fagan, Mark J., Sesso, Howard D., Gaziano, J. Michael
Background: There are limited data regarding the quality of cardiovascular risk reduction in primary care settings with a high prevalence of psychiatric disease.
Coffey, Christopher S, Hebert, Patricia R, Ritchie, Marylyn D, Krumholz, Harlan M, Gaziano, J Michael, Ridker, Paul M, ...
Psychiatric Disease and Hypercholesterolemia in an Urban Academic Primary Care Clinic
Kaplowitz, Rebekah A., Fagan, Mark J., Sesso, Howard D., Gaziano, J. Michael
Background: There are limited data regarding the quality of cardiovascular risk reduction in primary care settings with a high prevalence of psychiatric disease.
Li, Haojie, Stampfer, Meir J, Hollis, J. Bruce W, Mucci, Lorelei A, Gaziano, J. Michael, Hunter, David, ...
Results of this study by Haojie Li and colleagues suggest that vitamin D deficiency is common among men in the US, and that vitamin D status and genetic variation in theVDR gene affect prostate...
Aspirin and Decreased Adult-Onset Asthma: Randomized Comparisons from the Physicians' Health Study
Barr, R. Graham, Kurth, Tobias, Stampfer, Meir J., Buring, Julie E., Hennekens, Charles H., Gaziano, J. Michael
Rationale: In an observational cohort study, women who self-selected for frequent aspirin use developed less newly diagnosed asthma than women who did not take aspirin.
Migraine, vascular risk, and cardiovascular events in women: prospective cohort study
Kurth, Tobias, Schürks, Markus, Logroscino, Giancarlo, Gaziano, J Michael, Buring, Julie E
Objectives To evaluate whether the association between migraine with aura and increased risk of cardiovascular disease is modified by vascular risk groups as measured by the Framingham risk score for...
Incidence of cardiovascular disease and cancer in advanced age: prospective cohort study
Driver, Jane A, Djoussé, Luc, Logroscino, Giancarlo, Gaziano, J Michael, Kurth, Tobias
Objective To investigate the influence of increasing age on the incidence and remaining lifetime risk of cardiovascular disease and cancer in a cohort of older men.
Lou, Hong, Yeager, Meredith, Li, Hongchuan, Bosquet, Jesus Gonzalez, Hayes, Richard B., Orr, Nick, ...
Two recent genome-wide association studies have independently identified a prostate cancer susceptibility locus on chromosome 10q11.2. The most significant single-nucleotide polymorphism (SNP) marker...
Prospective Cohort Study of Type 2 Diabetes and the Risk of Parkinson's Disease
Driver, Jane A., Smith, Ashley, Buring, Julie E., Gaziano, J. Michael, Kurth, Tobias, Logroscino, Giancarlo
OBJECTIVE—To evaluate the association between type 2 diabetes and newly reported Parkinson's disease.