Scientific Commons: J. Montreuil

Primary structure of glycoprotein glycans (1995)

Conformational analysis of the sialyla(2®3/6)N-acetyllactosamine structural element occurring in glycoproteins, by two-dimensional NOE 1H-NMR spectroscopy in combination with energy calculations by hard-sphere exo-anomeric and molecular mechanics force-field with hydrogen-bonding potential (1989)

Vliegenthart, J.F.G., Breg, J., Strecker, G., Montreuil, J.

The conformation is described of the sialylalpha(2-> 3/6)N-acetyllactosamine structural element, frequently occurring in glycoproteins. NOE spectroscopy of NeuAcalpah(2-> 3) Galbeta(1->...

Primary structure of the major O-glycosidically linked carbohydrate unit of human Von Willebrand Factor (1989)

Vliegenthart, J.F.G., Samor, B., Mazurier, C., Goudemand, M., Waard, P. De, ...

Scope and limitations of rotating-frame nuclear overhauser enhancement spectroscopy applied to oligosaccharides (1988)

Breg, J., Romijn, D., Vliegenthart, J.F.G., Strecker, G., Montreuil, J.

Two-dimensional rotating-frame nuclear Overhauser enhancement spectroscopy has been applied to milk oligosaccharides containing the blood-group determinants Lea, Led, or Leb. The results indicate a...

Scope and limitations of rotating-frame nuclear Overhauser enhancement spectroscopy applied to oligosaccharides (1988)

Vliegenthart, J.F.G., Breg, J., Romijn, D., Strecker, G., Montreuil, J.

Two-dimensional rotating-frame nuclear Overhauser enhancement spectroscopy has been applied to milk oligosaccharides containing the blood-group determinants Lea, Led, or Leb. The results indicate a...

Primary structure of the glycans of porcine pancreatic lipase (1987)

Vliegenthart, J.F.G., Fournet, B., Leroy, Y., Montreuil, J., Decaro, J., Rovery, M., ...

Structure of the monosialyl oligosaccharides derived from salivary gland mucin glycoproteins of the Chinese swiftlet (genus Collocalia). Characterization of novel types of extended core structure, Galb(1®3)[GlcNAcb(1®6)]GalNAca(1®3)GalNAc(-ol), and of chain termination, [Gala(1®4)]0-1[Galb(1®4)]2GlcNAcb(1®.) (1987)

Vliegenthart, J.F.G., Montreuil, J., Strecker, G., Peter-Katalinic, J., ...

The mucus glycoproteins, the so-called nest-cementing substance, from the salivary gland of Chinese swiftlets (genus Collocalia) are mainly constituted of sialic acid-rich O-glycosylproteins....

Primary structure of a new tetraantennary glycan of the N-acetyllactosaminic type isolated from human factor VIII/von Willebrand factor (1986)

Vliegenthart, J.F.G., Samor, B., Debray, H., Mazurier, C., Goudemand, M., ...

Primary structure of the oligosaccharide moiety of hemocyanin from the scorpion Androctonus australis (1986)

Vliegenthart, J.F.G., Debeire, P., Montreuil, J., Goyffon, M., Kuik, J.A. Van, Halbeek, H. Van

Hemocyanin, the copper-containing glycoprotein that serves as an oxygen carrier in the hemolymph of some arthropods and molluscs, was obtained from the blood of the scorpion Androctonus australis....

Primary structure of two major glycans of bovine fibrinogen (1985)

Vliegenthart, J.F.G., Debeire, P., Montreuil, J., Moczar, E., Halbeek, H. Van

Primary structure of two sialylated triantennary glycans from human serotransferrin (1985)

Vliegenthart, J.F.G., Spik, G., Debruyne, V., Montreuil, J., Halbeek, H. Van

Glycopeptides obtained from human serotransferrin by pronase digestion were separated into two fractions by affinity chromatography on Con A-Sepharose. The retarded fraction (85% of total...

Structure primaire des chaines glycanniques de linhibiteur de Cl estérase normal (CT-INH) après lanalyse en RMN à 400-MHz (1985)

Vliegenthart, J.F.G., Strecker, G., Halbeek, H. Van, Montreuil, J., Hartmann, L.

Primary structure of N-glycosidically linked asialoglycans of secretory immunoglobulins A from human milk (1984)

Vliegenthart, J.F.G., Pierce-Crétel, A., Debray, H., Montreuil, J., Spik, G., Halbeek, H. Van, ...

Primary structure of the major glycans of the N-acetyllactosamine type derived from the human immunoglobulins M from two patients with Waldenströms macroglobulinemia (1984)

Vliegenthart, J.F.G., Cahour, A., Debeire, P., Hartmann, L., Montreuil, J., Halbeek, H. Van

The carbohydrate chains of the pathological human immunoglobulins M from two patients with Waldenström's macroglobulinemia were released by hydrazinolysis. The N-acetyllactosamine-type glycans were...

The structure of a trisialyl di-antennary N-type glycopeptide obtained from rat plasma hemopexin (1984)

Vliegenthart, J.F.G., Bernard, N., Engler, R., Strecker, G., Montreuil, J., Halbeek, H. Van

Natural-abundance 13C-NMR spectroscopy of two glyco-asparagines derived from the core of N-glycosidic carbohydrate chains (1983)

Vliegenthart, J.F.G., Dijkstra, B.W., Strecker, G., Montreuil, J.

13C-NMR spectroscopic studies were carried out on Manalpha(1->6)Man beta(1->4)GlcNAc beta(1->4)GlcNAc beta(1->N)-Asn and Man alpha(1->6)Man beta(1->4)GlcNAc beta(1->4)[Fuc alpha(1->6)]GlcNAc...

Primary structure of a novel N-glycosidic carbohydrate unit, derived from hen ovomucoid (1983)

Vliegenthart, J.F.G., Paz Parente, J., Strecker, G., Leroy, Y., Montreuil, J., Fournet, B., ...

The N-glycosidic carbohydrate chains of hen -ovomucoid were released from the protein by hydrazinolysis, and separated by HPLC. Primary structural analysis of 3 major fractions was conducted by...

Primary structure of the oligosaccharide determinant of blood group Cad specificity (1983)

Vliegenthart, J.F.G., Blanchard, D., Fournet, B., Montreuil, J., Halbeek, H. Van

Glycophorin A and B from Cad erythrocyte membranes are the carriers of the blood group Cad determinants. They are characterized by a significant increase in molecular mass, as compared to the...

Primary structure of three mannosyl-glycoasparagines and nine sialyl-oligosaccharides isolated from the urine of two patients with Gauchers disease (infantile form) (1983)

Vliegenthart, J.F.G., Montreuil, J., Strecker, G., Halbeek, H. Van, Dorland, L., ...

Structural studies of the glycans isolated from rat plasma hemopexin (1983)

Vliegenthart, J.F.G., Bernard, N., Lombart, G., Strecker, G., Montreuil, J., Halbeek, H. Van

Structure determination of the major asparagine-linked sugar chain of human factor VIII - von Willebrand factor (1983)

Vliegenthart, J.F.G., Debeire, P., Montreuil, J., Samor, B., Mazurier, C., Goudemand, M., ...

N-glycosidically-linked glycans released by hydrazinolysis of human factor VIII/von Willebrand factor (FVIII/vWf) were seperated by high-voltage electrophoresis. Five fraction were obtained, one of...

A novel type of carbohydrate structure present in hen ovomucoid (1982)

Vliegenthart, J.F.G., Paz Parente, J., Strecker, G., Montreuil, J., Fournet, B., ...

Hen ovomucoid is characterized by a high degree of microheterogeneity of its carbohydrate moieties, as was recently demonstrated by hydrazinolysis in combination with high performance liquid...

Primary structure of the glycans from human lactotransferrin (1982)

Vliegenthart, J.F.G., Spik, G., Strecker, G., Fournet, B., Bouquelet, S., Montreuil, J., ...

Primary structure of the N-glycosidically linked sialoglycans of secretory immunoglobulins A from human milk (1982)

Vliegenthart, J.F.G., Pierce-Crétel, A., Pamblanco, M., Strecker, G., Montreuil, J., Spik, G., ...

The structures and microheterogeneity of the carbohydrate chains of human plasma ceruloplasmin : A study employing 500-MHz 1H-NMR spectroscopy (1982)

Vliegenthart, J.F.G., Endo, M., Suzuki, K., Schmid, K., Fournet, B., Karamanos, Y., ...

Characterization of the microheterogeneity in glycoproteins by 500-MHz 1H-NMR spectroscopy of glycopeptide preparations : Application to a monofucosylated tetra-antennary glycopeptide fraction from human plasma a1-acid glycoprotein (1981)

Vliegenthart, J.F.G., Halbeek, H. Van, Dorland, L., Montreuil, J., Fournet, B., Schmid, K.

Five hundred-MHz 1H-NMR spectroscopy was employed to study a monofucosylated tetra-antennary glycopeptide fraction which was derived from human plasma a1-acid glycoprotein. This fraction was earlier...

Structure determination by 360-MHz 1H-NMR spectroscopy and methylation analysis of a biantennary glycan of the N-acetyllactosaminic type isolated from rat-liver plasma membrane (1981)

Vliegenthart, J.F.G., Debray, H., Fournet, B., Montreuil, J., Dorland, L.

Structure determination of oligosaccharides isolated from A+, H+ and A- H- hog-submaxillary-gland mucin glycoproteins, by 360-MHz 1H-NMR spectroscopy, permethylation analysis and mass spectrometry (1981)

Vliegenthart, J.F.G., Halbeek, H. Van, Dorland, L., Haverkamp, J., Veldink, G.A., Fournet, B., ...

Structure determination of two oligomannoside-type glycopeptides obtained from bovine lactotransferrin, by 500 MHz 1H-NMR spectroscopy (1981)

Vliegenthart, J.F.G., Halbeek, H. Van, Dorland, L., Spik, G., Chéron, A., Montreuil, J.

Structures of fifteen oligosaccharides isolated from new-born meconium (1981)

Vliegenthart, J.F.G., Montreuil, J., Strecker, G., Dorland, L., Halbeek, H. Van, ...

New born meconium contains at least a hundred oTigosaccharides. In this study the isolation and characterization of the major constituents is described. The structure elucidation of 15 neutral and...

Structure elucidation of oligomannoside-type asparagine-bound carbohydrate chains of glycoproteins by 500 MHz 1H NMR spectroscopy (1980)

Halbeek, H. Van, Dorland, L., Veldink, G.A., Vliegenthart, J.F.G., Montreuil, J., ...

A 500 MHz 1H NMR study of urinary oligosaccharides from patients with mannosidosis (1980)

Halbeek, H. Van, Dorland, L., Veldink, G.A., Vliegenthart, J.F.G., Strecker, G., ...

A 500 MHz 1H NMR study of urinary oligosaccharides from patients with mannosidosis (1980)

Vliegenthart, J.F.G., Halbeek, H. Van, Dorland, L., Veldink, G.A., Strecker, G., ...

Structure elucidation of oligomannoside-type asparagine-bound carbohydrate chains of glycoproteins by 500 MHz 1H NMR spectroscopy (1980)

Vliegenthart, J.F.G., Halbeek, H. Van, Dorland, L., Veldink, G.A., Montreuil, J., ...

The application of 500-MHz 1H-NMR spectroscopy for the structure elucidation of N-acetyllactosamine type asparagine-bound carbohydrate chains of glycoproteins (1980)

Vliegenthart, J.F.G., Halbeek, H. Van, Dorland, L., Schmid, K., Montreuil, J., Fournet, B., ...

Investigation by 360-MHz 1H-nuclear-magnetic-resonance spectroscopy and methylation analysis of the single glycan chain of chicken ovotransferrin (1979)

Vliegenthart, J.F.G., Dorland, L., Haverkamp, J., Spik, G., Fournet, B., Montreuil, J.

Primary structure and conformation of glycans N-glycosidically linked to peptide chains (1979)

Vliegenthart, J.F.G., Montreuil, J.

Structure of 10 glycopeptides from a1-acid glycoprotein (1979)

Vliegenthart, J.F.G., Fournet, B., Strecker, G., Spik, G., Montreuil, J., Schmid, K., ...

The primary structure of the asialo-carbohydrate units of the first glycosylation site of human plasma a1-acid glycoprotein (1979)

Vliegenthart, J.F.G., Schmid, K., Binette, J.P., Dorland, L., Fournet, B., Montreuil, J.

360-MHz 1H nuclear-magnetic-resonance spectroscopy of sialyl-oligosaccharides from patients with sialidosis (mucolipidosis I and II) (1978)

Vliegenthart, J.F.G., Dorland, L., Haverkamp, J., Strecker, G., Fournet, B., ...

360-MHz proton nuclear magnetic resonance spectra were recorded of 10 sialyl-oligosaccharides isolated form urine of sialidosis patients. Their structures are related to the complex...

Determination by 360 MHz 1H NMR spectroscopy of the type of branching in complex asparagine-linked glycan chains of glycoproteins (1978)

Vliegenthart, J.F.G., Dorland, L., Haverkamp, J., Fournet, B., Strecker, G., Spik, G., ...

Determination of the primary structures of 16 asialo-carbohydrate units derived from human plasma a1-acid glycoprotein by 360-MHz 1H NMR spectroscopy and permethylation analysis (1978)

Vliegenthart, J.F.G., Fournet, B., Montreuil, J., Strecker, G., Dorland, L., Haverkamp, J., ...

The present study was initiated in order to determine the primary structures of the carbohydrate units of desialyzed human plasma al-acid glycoprotein. In an earlier investigation I6 glycopeptides...

Structure of the three major fucosyl-glycoasparagines accumulating in the urine of a patient with fucosidosis (1978)

Vliegenthart, J.F.G., Strecker, G., Fournet, B., Montreuil, J., Dorland, L., Haverkamp, J., ...

Structural studies on 2-acetamido-1-N-(4-L-aspartyl)-2-deoxy-β-D-glucopyranosylamine and 2-acetamido-6-O-(α-L-fucopyranosyl)-1-N-(4-L-aspartyl)-2-deoxy-β-D-glucopyranosylamine by 360-MHz proton-magnetic-resonance spectroscopy (1977)

Vliegenthart, J.F.G., Dorland, L., Schut, B.L., Strecker, G., Fournet, B., Spik, G., ...

The 360-MHz proton magnetic resonance spectra of 2-acetamido-1-N-(4-l-aspartyl)- 2-deoxy-beta-d-glucopyranosylamine (GlcNAc beta1-> Asn) and 2-acetamido-6-O-(alpha-l-fucopyranosyl)-1-N...

Structure of seven oligosaccharides excreted in the urine of a patient with Sandhoffs disease (GM2 gangliosidosis-variant O) (1977)

Vliegenthart, J.F.G., Strecker, G., Fournet, B., Montreuil, J., Dorland, L., ...

The structure of the asialo-carbohydrate units of human serotransferrin as proven by 360 MHz proton magnetic resonance spectroscopy (1977)

Vliegenthart, J.F.G., Dorland, L., Haverkamp, J., Schut, B.L., Spik, G., Strecker, G., ...

Isolation and identification of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid from the urine of a patient with sialuria (1975)

Vliegenthart, J.F.G., Kamerling, J.P., Schauer, R., Strecker, G., Montreuil, J.

-Acetylneuraminic acid preparations from the urine of a patient with sialuria contain 12% of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid. This new human sialic acid was isolated by ion-exchange and...

Comparative study of asparagine-linked glycans of plasma T-kininogen in normal rats and during acute inflammation.

Baussant, T, Alonso, C, Wieruszeski, J M, Strecker, G, Montreuil, J, Alhenc-Gelas, F, ...

Rat T-kininogen has been separated into two molecular variants by affinity chromatography on concanavalin A (ConA): a ConA-reactive (ConA+) and a ConA-non-reactive (ConA-) fraction, from which...

Properties of the iron-binding site of the N-terminal lobe of human and bovine lactotransferrins. Importance of the glycan moiety and of the non-covalent interactions between the N- and C-terminal lobes in the stability of the iron-binding site.

Legrand, D, Mazurier, J, Colavizza, D, Montreuil, J, Spik, G

The recent determination by X-ray diffraction of the tridimensional structure of human lactotransferrin has underlined the presence of two lobes, each composed of two domains, I and II, as well as...

Primary structure of glycans isolated from human leucocyte lactotransferrin. Absence of fucose residues questions the proposed mechanism of hyposideraemia.

Derisbourg, P, Wieruszeski, J M, Montreuil, J, Spik, G

Lactotransferrin was highly purified from lysates of human neutrophilic leucocytes by immuno-affinity chromatography. A comparative analysis of the molar carbohydrate compositions of human leucocyte...

1H-and 13C-n.m.r. spectroscopy of 2-oxo-3-deoxy-D-glycero-D- galactononulosonic acid-containing oligosaccharide-alditols bearing Lewis X, Lewis Y and A-Lewis Y determinants isolated from the jelly coat of Pleurodeles waltl eggs.

Strecker, G, Wieruszeski, J M, Michalski, J C, Montreuil, J

Three acidic oligosaccharide-alditols carrying Lewis X, Lewis Y and A-Lewis Y determinants were isolated from the jelly coat of Pleurodeles waltl eggs. These compounds possess the following...

Physiological significance of the marked increased branching of the glycans of human serotransferrin during pregnancy.

Léger, D, Campion, B, Decottignies, J P, Montreuil, J, Spik, G

Human serotransferrin (Tf) presents a microheterogeneity based on the existence of biantennary and triantennary glycans of the N-acetyl-lactosaminic type. By affinity chromatography on a concanavalin...

Lactoferrin-lipopolysaccharide interaction: involvement of the 28-34 loop region of human lactoferrin in the high-affinity binding to Escherichia coli 055B5 lipopolysaccharide.

Elass-Rochard, E, Roseanu, A, Legrand, D, Trif, M, Salmon, V, Motas, C, ...

The ability of lactoferrin (Lf), an iron-binding glycoprotein that is also called lactotransferrin, to bind lipopolysaccharide (LPS) may be relevant to some of its biological properties. A knowledge...

Evidence for interactions between the 30 kDa N- and 50 kDa C-terminal tryptic fragments of human lactotransferrin.

Legrand, D, Mazurier, J, Aubert, J P, Loucheux-Lefebvre, M H, Montreuil, J, Spik, G

Gel filtration of a mild tryptic digest of diferric human lactotransferrin carried out in presence of 10% (v/v) acetic acid led to the isolation of two fragments, an N-terminal tryptic fragment...

Primary structure of the glycans from mouse serum and milk transferrins.

Leclercq, Y, Sawatzki, G, Wieruszeski, J M, Montreuil, J, Spik, G

A 'serotransferrin-like' protein was purified from mouse milk. This serotransferrin cross-reacts immunologically with the serotransferrin isolated from mouse plasma and not with the mouse...

Lactotransferrin receptor of mouse small-intestinal brush border. Binding characteristics of membrane-bound and triton X-100-solubilized forms.

Hu, W L, Mazurier, J, Sawatzki, G, Montreuil, J, Spik, G

A specific lactotransferrin receptor was identified in the mouse small-intestinal brush-border membrane and the binding features were investigated in homologous and heterologous systems. The receptor...

Inhibition of the specific binding of human lactotransferrin to human peripheral-blood phytohaemagglutinin-stimulated lymphocytes by fluorescein labelling and location of the binding site.

Legrand, D, Mazurier, J, Maes, P, Rochard, E, Montreuil, J, Spik, G

Labelling of human lactotransferrin with fluorescein 5'-isothiocyanate (FITC) in an equimolar ratio inhibits the binding of the protein to phytohaemagglutinin-activated human peripheral-blood...

Comparative study of the carbohydrate moieties of normal and pathological human immunoglobulins M.

Cahour, A, Debeire, P, Hartmann, L, Montreuil, J

The well-known heterogeneity of normal and pathological immunoglobulins M was investigated in a study involving the characterization of their carbohydrate moieties. Oligosaccharide units were...

Cytosolic location of an endo-N-acetyl-beta-D-glucosaminidase activity in rat liver and kidney.

Pierce, R J, Spik, G, Montreuil, J

Endo-N-acetyl-beta-D-glucosaminidase activity towards an oligomannosidic type glycoamino acid substrate was found in the soluble fraction of rat liver and kidney. No evidence for a lysosomal form of...

Demonstration and cytosolic location of an endo-N-acetyl-beta-D-glucosaminidase activity towards an asialo-N-acetyl-lactosaminic-type substrate in rat liver.