J. Mouradian

Immunotherapy with anti-CD3 monoclonal antibodies and recombinant interleukin 2: stimulation of molecular programs of cytotoxic killer cells and induction of tumor regression.

Nakajima, F, Khanna, A, Xu, G, Lagman, M, Haschemeyer, R, Mouradian, J, ...

Adoptive cellular immunotherapy, infusions of interleukin 2 (IL-2) in conjunction with in vitro-activated killer cells, has brought new hope to patients with cancer. The broad application of this...

Immunotherapy with anti-CD3 monoclonal antibodies and recombinant interleukin 2: stimulation of molecular programs of cytotoxic killer cells and induction of tumor regression.

Nakajima, F, Khanna, A, Xu, G, Lagman, M, Haschemeyer, R, Mouradian, J, ...

Adoptive cellular immunotherapy, infusions of interleukin 2 (IL-2) in conjunction with in vitro-activated killer cells, has brought new hope to patients with cancer. The broad application of this...

Analysis of autoantibody production in SCID-systemic lupus erythematosus (SLE) chimeras.

Ashany, D, Hines, J, Gharavi, A, Mouradian, J, Elkon, K B

Mice with SCID disease have previously been successfully engrafted with human peripheral blood mononuclear cells (PBMC) obtained from normal individuals and from patients with various diseases. To...

MRL/lpr-->severe combined immunodeficiency mouse allografts produce autoantibodies, acute graft-versus-host disease or a wasting syndrome depending on the source of cells.

Ashany, D, Hines, J J, Gharavi, A E, Mouradian, J, Drappa, J, Elkon, K B

MRL/lpr (lpr) mice spontaneously develop a lupus-like illness as well as massive lymphadenopathy. Attempts to transfer autoimmunity by adoptive transfer or radiation bone marrow chimeras have been...