Barker, J N, Sarma, V, Mitra, R S, Dixit, V M, Nickoloff, B J
T lymphocytes and mononuclear cells preferentially accumulate in the epidermis in inflammatory skin disease. To determine the role of keratinocytes in both the chemotaxis and adhesion of these cells...
Barker, J N, Sarma, V, Mitra, R S, Dixit, V M, Nickoloff, B J
T lymphocytes and mononuclear cells preferentially accumulate in the epidermis in inflammatory skin disease. To determine the role of keratinocytes in both the chemotaxis and adhesion of these cells...
Langerhans' cell expression of the selectin ligand, sialyl Lewis x.
Ross, E L, Barker, J N, Allen, M H, Chu, A C, Groves, R W, MacDonald, D M
Cellular adhesion molecules play a central role in leucocyte migration through peripheral blood and tissues. A crucial stage in these events in selectin-mediated adhesion involving E-selectin...
Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.
Nickoloff, B. J., Karabin, G. D., Barker, J. N., Griffiths, C. E., Sarma, V., Mitra, R. S., ...
The importance of immunologic mechanisms in psoriasis has been deduced from the ability of immunosuppressive therapies to ameliorate this common and chronic skin disease. Certainly the histology of...
Barker, J. N., Jones, M. L., Mitra, R. S., Crockett-Torabe, E., Fantone, J. C., Kunkel, S. L., ...
Interactions between T lymphocytes, neutrophils, and epidermal cells are believed to play a central role in the pathophysiology of psoriasis and other inflammatory cutaneous disorders. Although there...
Nickoloff, B. J., Mitra, R. S., Shimizu, Y., Barker, J. N., Karabin, G., Stoof, T., ...
The initial in vitro observation that cultured keratinocytes, when treated with cytokines such as gamma interferon, increased the binding of T lymphocytes, opened up a whole new avenue of research to...
Barker, J. N., Goodlad, J. R., Ross, E. L., Yu, C. C., Groves, R. W., MacDonald, D. M.
Recombinant human interferon-gamma was administered intradermally (10 micrograms in 0.1 ml) to healthy adult human volunteers from day 1 to day 3, and epidermal cell proliferation was measured on...
Expression of selectin ligands by cutaneous squamous cell carcinoma.
Groves, R. W., Allen, M. H., Ross, E. L., Ahsan, G., Barker, J. N., MacDonald, D. M.
Recent evidence suggests that interactions between endothelial selectins and tumor surface selectin ligands may be of importance in cancer metastasis. To investigate the role of such mechanisms in...