Premeiotic Clusters of Mutation and the Cost of Natural Selection (2004)
Woodruff, R. C., Thompson, J. N., Gu, S.
Haldane stated that there is a cost of natural selection for new beneficial alleles to be substituted over time. Most of this cost, which leads to “genetic deaths,” is in the early generations of...
DESIGN OF CUSHIONING SYSTEMS FOR AIR DELIVERY OF EQUIPMENT (2002)
ELLIS, BILLY C., RIPPERGER, E. A., THOMPSON, J. N.
A description of effective systems is given by which the impact on ground contact may be reduced within permissible limits through the use of cushioning materials. In addition to theory of...
Keeling, Kim M., Brooks, D. A., Hopwood, J. J., Li, Peining, Thompson, J. N., Bedwell, David M.
Copyright © 2001 Oxford University Press
Keeling, Kim M., Brooks, D. A., Hopwood, J. J., Li, Peining, Thompson, J. N., Bedwell, David M.
Copyright © 2001 Oxford University Press
Multiple occurrences of mutualism in the yucca moth lineage.
The complex mutualism between yuccas and the moths that pollinate their flowers is regarded as one of the most obvious cases of coevolution. Studies of related genera show that at least two of the...
Increased mutation in crosses between geographically separated strains of Drosophila melanogaster.
Mutator activity associated with the common male recombination (MR) chromosomes in Drosophila melanogaster appears to be suppressed in natural populations. Crosses between geographically separated...
The preparation and biological activity of methyl 5,6-epoxy-retinoate
1. Oxidation of methyl retinoate with monoperphthalic acid gave methyl 5,6-epoxyretinoate, obtained as pale-yellow crystals, m.p. 89°. 2. The structure of the epoxide was confirmed by its...
Focal liver lesions: a plan for management.
Thompson, J N, Gibson, R, Czerniak, A, Blumgart, L H
A management plan for patients with suspected focal liver lesions which avoids early biopsy includes routine laboratory investigations, ultrasound scanning, and assessment for evidence of...
Obscure gastrointestinal haemorrhage of small-bowel origin.
Thompson, J N, Hemingway, A P, McPherson, G A, Rees, H C, Allison, D J, Spencer, J
The records of 37 patients investigated for obscure gastrointestinal haemorrhage originating from the small bowel were reviewed retrospectively. Bleeding was caused by Meckel's diverticula in eight...
Henderson, S. A., Woodruff, R. C., Thompson, J. N.
An inbred line (OK1) of Drosophila melanogaster , recently derived from a natural population in Oklahoma, has been found by Woodruff and Thompson to exhibit a low frequency of spontaneous male...
Gall bladder function after endoscopic sphincterotomy.
Desa, L A, Grace, P A, Vipond, M N, Henderson, B, Thompson, J N
Multiple occurrences of mutualism in the yucca moth lineage.
The complex mutualism between yuccas and the moths that pollinate their flowers is regarded as one of the most obvious cases of coevolution. Studies of related genera show that at least two of the...
Increased mutation in crosses between geographically separated strains of Drosophila melanogaster.
Mutator activity associated with the common male recombination (MR) chromosomes in Drosophila melanogaster appears to be suppressed in natural populations. Crosses between geographically separated...
Henderson, S. A., Woodruff, R. C., Thompson, J. N.
An inbred line (OK1) of Drosophila melanogaster , recently derived from a natural population in Oklahoma, has been found by Woodruff and Thompson to exhibit a low frequency of spontaneous male...
The preparation and biological activity of methyl 5,6-epoxy-retinoate
1. Oxidation of methyl retinoate with monoperphthalic acid gave methyl 5,6-epoxyretinoate, obtained as pale-yellow crystals, m.p. 89°. 2. The structure of the epoxide was confirmed by its...
Focal liver lesions: a plan for management.
Thompson, J N, Gibson, R, Czerniak, A, Blumgart, L H
A management plan for patients with suspected focal liver lesions which avoids early biopsy includes routine laboratory investigations, ultrasound scanning, and assessment for evidence of...
Obscure gastrointestinal haemorrhage of small-bowel origin.
Thompson, J N, Hemingway, A P, McPherson, G A, Rees, H C, Allison, D J, Spencer, J
The records of 37 patients investigated for obscure gastrointestinal haemorrhage originating from the small bowel were reviewed retrospectively. Bleeding was caused by Meckel's diverticula in eight...
Gall bladder function after endoscopic sphincterotomy.
Desa, L A, Grace, P A, Vipond, M N, Henderson, B, Thompson, J N
Plant polyploidy and non-uniform effects on insect herbivores.
Genomic duplication through polyploidy has played a central role in generating the biodiversity of flowering plants. Nonetheless, how polyploidy shapes species interactions or the ecological dynamics...
Gene flow and geographically structured coevolution
Nuismer, S. L., Thompson, J. N., Gomulkiewicz, R.
Many of the dynamic properties of coevolution may occur at the level of interacting populations, with local adaptation acting as a force of diversification, as migration between populations...
Which patients with suspected appendicitis should undergo laparoscopy?
Paterson-Brown, S, Thompson, J N, Eckersley, J R T, Ponting, G A, Dudley, H A F
Fibrinolysis and the biliary tree.
Scott-Coombes, D M, Whawell, S A, Havranek, E G, Thompson, J N
AIMS: To investigate the fibrinolytic activity of normal and calculous human bile. METHODS: Fibrinolytic properties of the biliary tract were studied in patients with gall bladder stones (n = 7)...
Fibrinolytic activity of ascites caused by alcoholic cirrhosis and peritoneal malignancy.
Scott-Coombes, D M, Whawell, S A, Vipond, M N, Crnojevic, L, Thompson, J N
Coagulopathy is a well recognised complication of peritoneovenous shunting for ascites. The relative contributions of primary fibrinolysis and disseminated intravascular coagulation remain...
Specialist investigation of obscure gastrointestinal bleeding.
Thompson, J N, Salem, R R, Hemingway, A P, Rees, H C, Hodgson, H J, Wood, C B, ...
The investigation and treatment of 131 patients with 'obscure' gastrointestinal bleeding has been reviewed. One hundred and six patients were assessed electively for recurrent haemorrhage, 25...
Thompson, J N, Barr, J A, Collier, N, Spencer, J, Bush, A, Cope, L, ...
Gastric secretion was measured in nine patients with duodenal ulcer before, and after treatment for four weeks with omeprazole 20 mg or 40 mg daily. Basal acidity and acid output were affected...
Man, W K, Thompson, J N, Baron, J H, Spencer, J
Gastric mucosal concentrations of histamine and of its metabolic enzyme, histamine methyltransferase activity, were measured in patients with duodenal ulcer disease and patients with an apparently...
Gong, Yi, Woodruff, R.C, Thompson, J.N
New deleterious mutations may reduce health and fitness and are involved in the evolution and maintenance of numerous biological processes. Hence, it is important to estimate the deleterious genomic...
Selective visceral angiography in obscure postoperative gastrointestinal bleeding.
Ng, B. L., Thompson, J. N., Adam, A., Spencer, J., Hemingway, A. P., Blumgart, L. H., ...
Postoperative gastrointestinal bleeding may be difficult to diagnose and treat. Selective visceral angiography localised the bleeding site in seven out of ten episodes of obscure postoperative...
General surgeons' attitudes to the treatment and prevention of abdominal adhesions.
Scott-Coombes, D. M., Vipond, M. N., Thompson, J. N.
A questionnaire survey of general surgeons was undertaken to estimate the incidence of abdominal adhesions as a clinical problem and to establish current attitudes to the treatment of adhesional...
Experimental adhesion prophylaxis with recombinant tissue plasminogen activator.
Vipond, M. N., Whawell, S. A., Scott-Coombes, D. M., Thompson, J. N., Dudley, H. A.
The deposition of fibrin in the peritoneal cavity leads to fibrous adhesion formation. Recombinant tissue plasminogen activator (rtPA), delivered locally, was investigated as a method of preventing...
Wilson, M. S., Ellis, H., Menzies, D., Moran, B. J., Parker, M. C., Thompson, J. N.
Small bowel obstruction is a significant surgical problem and is commonly caused by postoperative adhesions. Patients suffering from this condition are often difficult to assess and require careful...