Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme.
Ojwang, J O, Hampel, A, Looney, D J, Wong-Staal, F, Rappaport, J
Ribozymes are RNAs that possess the dual properties of RNA sequence-specific recognition, analogous to conventional antisense molecules, and RNA substrate destruction via site-specific cleavage. The...
Ojwang, J O, Buckheit, R W, Pommier, Y, Mazumder, A, De Vreese, K, Esté, J A, ...
T30177, an oligonucleotide composed of only deoxyguanosine and thymidine, is 17 nucleotides in length and contains single phosphorothioate internucleoside linkages at its 5' and 3' ends for...
Ojwang, J O, Bhattacharya, B K, Marshall, H B, Korba, B E, Revankar, G R, Rando, R F
The nucleoside analog 2,4-diamino-7-(2-deoxy-2-fluoro-beta-D- arabinofuranosyl)pyrrolo[2,3-d]pyrimidine (T70080) and several related compounds were evaluated for anti-hepatitis B virus (HBV) activity...
Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme.
Ojwang, J O, Hampel, A, Looney, D J, Wong-Staal, F, Rappaport, J
Ribozymes are RNAs that possess the dual properties of RNA sequence-specific recognition, analogous to conventional antisense molecules, and RNA substrate destruction via site-specific cleavage. The...
Ojwang, J O, Buckheit, R W, Pommier, Y, Mazumder, A, De Vreese, K, Esté, J A, ...
T30177, an oligonucleotide composed of only deoxyguanosine and thymidine, is 17 nucleotides in length and contains single phosphorothioate internucleoside linkages at its 5' and 3' ends for...
Ojwang, J O, Bhattacharya, B K, Marshall, H B, Korba, B E, Revankar, G R, Rando, R F
The nucleoside analog 2,4-diamino-7-(2-deoxy-2-fluoro-beta-D- arabinofuranosyl)pyrrolo[2,3-d]pyrimidine (T70080) and several related compounds were evaluated for anti-hepatitis B virus (HBV) activity...