J. P.

Review- Gene pyramiding as a Bt resistance management strategy: How sustainable is this strategy? (2006)

  • Manyangarirwa,
  • W.,
  • Turnbul,
  • M.,
  • McCutcheon,
  • G.S.,
  • ...

Reports on the emergence of insect resistance to Bacillus thuringiensis   delta endotoxins have raised doubts on the sustainability of Bt-toxin based pest management technologies. Corporate industry...

Milton Keynes Park Revisited: changes in internal temperatures (2006)

27-30 April 2006

The Jervell and Lange-Nielsen syndrome: natural history, molecular basis, and clinical outcome (2006)

  • Schwartz,
  • P.J.,
  • Spazzolini,
  • C.,
  • Crotti,
  • L.,
  • ...

BACKGROUND: Data on the Jervell and Lange-Nielsen syndrome (J-LN), the long-QT syndrome (LQTS) variant associated with deafness and caused by homozygous or compound heterozygous mutations on the...

Non-Gaussianity in the Very Small Array cosmic microwave background maps with smooth goodness-of-fit tests (2006)

We have used the Rayner and Best smooth tests of goodness-of-fit to study the Gaussianity of the Very Small Array (VSA) data. These tests are designed to be sensitive to the presence of `smooth'...

Disease and Disadvantage in the USA and in England. (2006)

  • Banks,
  • J.,
  • Marmot,
  • M.,
  • Oldfied,
  • Z.,
  • ...

Mycotoxigenic and Proteolytic Potential of Moulds Associated with Smoked Shark Fish (Chlamydoselachus anguincus   ) (2005)

Among the 33 moulds isolated from 20 samples of wood-smoked Chlamydoselachus anguincus   (shark-fish) 20 isolates were capable of producing metabolites toxic to fertile Hubbard Golden Comet (Niger...

Comunicação de massa, radiodifusão e polifonia: as estratégias de significação do movimento social (2005)

Trabalho apresentado no Intercom Júnior, evento componente do XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005  Este...

Jornalismo e Denúncia Social: O Papel da Imprensa e da Sociedade no Cumprimento dos Direitos Humanos, das Crianças e Adolescentes (2005)

Trabalho apresentado no Intercom Júnior, evento componente do XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005  Com a...

"Buy Nothing Day": a Internet como arma do ativismo glocal (2005)

Trabalho apresentado no Intercom Júnior, evento componente do XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005  Ao longo...

Status of the physics of substellar objects (2005)

  • Jones,
  • H.R.A.,
  • Viti,
  • S.,
  • Tennyson,
  • J.,
  • ...

Triplate fixation (2005)

  • Cobb,
  • J.P.,
  • Ashwood,
  • N.,
  • Robbins,
  • G.,
  • ...

Mutations within the transcription factor PROP1 are rare in a cohort of patients with sporadic combined pituitary hormone deficiency (CPHD) (2005)

  • Turton,
  • J.P.,
  • Mehta,
  • A.,
  • Raza,
  • J.,
  • ...

Objective Mutations within the pituitary-specific paired-like homeobox gene PROP1 have been described in 50-100% of patients with familial combined pituitary hormone deficiency (CPHD). We screened a...

Novel mutations within the POU1F1 gene associated with variable Combined Pituitary Hormone Deficiency (CPHD) (2005)

  • Turton,
  • J.P.,
  • Reynaud,
  • R.,
  • Mehta,
  • A.,
  • ...

CONTEXT: Mutations within the gene encoding the pituitary-specific transcription factor POU1F1 are associated with combined pituitary hormone deficiency (CPHD). Most of the affected individuals...

Circulating angiotensin converting enzyme activity is correlated with muscle strength (2005)

PURPOSE: The D-variant of the angiotensin-1 converting enzyme (ACE) gene is associated with higher circulating and tissue ACE activity. Some studies have suggested a similar association of genotype...

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates (2005)

  • Ross,
  • A.J.,
  • May-Simera,
  • H.,
  • Eichers,
  • E.R.,
  • ...

The evolutionarily conserved planar cell polarity (PCP) pathway (or noncanonical Wnt pathway) drives several important cellular processes, including epithelial cell polarization, cell migration and...

Opponent appetitive-aversive neural processes underlie predictive learning of pain relief (2005)

  • Seymour,
  • B.,
  • O'Doherty,
  • J.P.,
  • Koltzenburg,
  • M.,
  • ...

Termination of a painful or unpleasant event can be rewarding. However, whether the brain treats relief in a similar way as it treats natural reward is unclear, and the neural processes that underlie...

Heterozygous mutations of OTX2 cause severe ocular malformations (2005)

Major malformations of the human eye, including microphthalmia and anophthalmia, are examples of phenotypes that recur in families yet often show no clear Mendelian inheritance pattern. Defining loci...

Physical activity patterns in nonobese and obese children assessed using minute-by-minute accelerometry (2005)

  • Page,
  • A.,
  • Cooper,
  • A.R.,
  • Stamatakis,
  • E.,
  • ...

OBJECTIVE:To determine the levels and patterns of physical activity in a sample of obese (>/=99th percentile body mass index (BMI)) and nonobese (<99th percentile BMI) children.DESIGN:Cross-sectional...

Vasculopathy in Turner syndrome: arterial dilatation and intimal thickening without endothelial dysfunction (2005)

CONTEXT: Women with Turner syndrome (TS) have an increased cardiovascular mortality rate from both structural and ischemic heart disease, especially aortic dissection. OBJECTIVE: We hypothesized that...

Stem cells as future therapy in cardiology (2005)

This article focuses on the key studies relevant to the clinical application of stem-cell research in cardiovascular disease. The authors also discuss current and future directions in clinical...

In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A (2005)

  • Ivanova,
  • A.,
  • Signore,
  • M.,
  • Caro,
  • N.,
  • ...

We generated a ROSA26-eGFP-DTA mouse line by introducing an eGFP-DTA (enhanced green fluorescent protein - diphtheria toxin fragment A) cassette into the ROSA26 locus by homologous recombination in...

Initial application in the STS congenital database of complexity adjustment to evaluate surgical case mix and results (2005)

Background. The analysis of the second harvest (19982001) of the Society of Thoracic Surgeons Congenital Heart Surgery Database included the first attempt by the STS to apply a complexity-adjustment...

Exon array CGH: Detection of copy-number changes at the resolution of individual exons in the human genome (2005)

  • Dhami,
  • P.,
  • Coffey,
  • A.J.,
  • Abbs,
  • S.,
  • ...

The development of high-throughput screening methods such as array-based comparative genome hybridization (array CGH) allows screening of the human genome for copy-number changes. Current array CGH...

Early structural and functional changes of the vasculature in HIV-infected children: impact of disease and antiretroviral therapy (2005)

  • Charakida,
  • M.,
  • Donald,
  • A.E.,
  • Green,
  • H.,
  • ...

BACKGROUND: Premature cardiovascular disease is increasingly recognized in HIV-infected patients, but the mechanisms involved are unclear. The purpose of this study was to determine the impact of HIV...

Endothelial dysfunction in childhood infection (2005)

  • Charakida,
  • M.,
  • Donald,
  • A.E.,
  • Terese,
  • M.,
  • ...

BACKGROUND: Atherosclerosis begins in early life, and endothelial dysfunction is recognized as a key initiating event in the development of atherosclerosis. Although infection has been implicated in...

Mutations of the catalytic subunit of RAB3GAP cause Warburg Micro syndrome (2005)

  • Aligianis,
  • I.A.,
  • Johnson,
  • C.A.,
  • Gissen,
  • P.,
  • ...

Warburg Micro syndrome (WARBM1) is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. We identified...

Evidence from the Mars Express High Resolution Stereo Camera for a frozen sea close to Mars' equator (2005)

It is thought that the Cerberus Fossae fissures on Mars were the source of both lava and water floods(1,2-4) two to ten million years ago(1,2,5). Evidence for the resulting lava plains has been...

Assay and functional analysis of the ARL3 effector RP2 involved in X-linked retinitis pigmentosa (2005)

  • Evans,
  • R.J.,
  • Chapple,
  • J.P.,
  • Grayson,
  • C.,
  • ...

Mutations in RP2 cause X-linked retinitis pigmentosa and also macular and peripapillary atrophy. RP2 is a functional homologue of the tubulin folding cofactor, cofactor C, as it can replace the beta...

HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome (2005)

Protein degradation in eukaryotic cells usually involves the attachment of a ubiquitin chain to a substrate protein and its subsequent sorting to the proteasome. Molecular mechanisms underlying the...

Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2 (2005)

  • Inglis-Broadgate,
  • S.L.,
  • Ocaka,
  • L.,
  • Banerjee,
  • R.,
  • ...

Phototransduction in Drosophila is a phosphoinositide-mediated signalling pathway. Phosphatidylinositol 4,5-bisphosphate (PIP2) plays a central role in this process, and its levels are tightly...

Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy (2005)

Retinitis pigmentosa (RP) is a group of retinal degenerative diseases that are characterised primarily by the loss of rod photoreceptor cells. Mutations in rhodopsin are the most common cause of...

Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2 (2005)

  • Metherell,
  • L.A.,
  • Chapple,
  • J.P.,
  • Cooray,
  • S.,
  • ...

Familial glucocorticoid deficiency (FGD), or hereditary unresponsiveness to adrenocorticotropin (ACTH; OMIM 202200), is an autosomal recessive disorder resulting from resistance to the action of ACTH...

The role of canonical transient receptor potential 7 in B-cell receptor-activated channels (2005)

  • Lievremont,
  • J.P.,
  • Numaga,
  • T.,
  • Vazquez,
  • G.,
  • ...

Phospholipase C signaling stimulates Ca2+ entry across the plasma membrane through multiple mechanisms. Ca2+ store depletion stimulates store-operated Ca2+-selective channels, or alternatively, other...

CaSiO3 perovskite at lower mantle pressures. (2005)

  • Caracas,
  • R.,
  • Wentzcovitch,
  • R.,
  • Price,
  • G.D.,
  • ...

2004 UK E-Science All Hands Meeting (2004)

  • Chapman,
  • C.,
  • Wilson,
  • P.,
  • Tannenbaum,
  • T.,
  • ...

The regenerative plasticity of isolated urodele myofibers and its regulation by Msx1. (2004)

  • Kumar,
  • A.,
  • Velloso,
  • C.,
  • Imokawa,
  • Y.,
  • ...

The conversion of multinucleate postmitotic muscle fibers to dividing mononucleate progeny cells (cellularisation) occurs during limb regeneration in salamanders, but the cellular events and...

Cosmological parameter estimation using Very Small Array data out to l= 1500 (2004)

  • Rebolo,
  • R.,
  • Battye,
  • R.A.,
  • Carreira,
  • P.,
  • ...

We estimate cosmological parameters using data obtained by the Very Small Array (VSA) in its extended configuration, in conjunction with a variety of other cosmic microwave background (CMB) data and...

Estimating the bispectrum of the Very Small Array data (2004)

  • Smith,
  • S.,
  • Rocha,
  • G.,
  • Challinor,
  • A.,
  • ...

We estimate the bispectrum of the Very Small Array data from the compact and extended configuration observations released in 2002 December, and compare our results with those obtained from Gaussian...

High-sensitivity measurements of the cosmic microwave background power spectrum with the extended Very Small Array (2004)

  • Dickinson,
  • C.,
  • Battye,
  • R.A.,
  • Carreira,
  • P.,
  • ...

We present deep Ka-band (ν~ 33 GHz) observations of the cosmic microwave background (CMB) made with the extended Very Small Array (VSA). This configuration produces a naturally weighted...

Searching for non-Gaussianity in the Very Small Array data (2004)

  • Savage,
  • R.,
  • Battye,
  • R.A.,
  • Carreira,
  • P.,
  • ...

We have tested Very Small Array (VSA) observations of three regions of sky for the presence of non-Gaussianity, using high-order cumulants, Minkowski functionals, a wavelet-based test and a Bayesian...

The Use of X-Ray Computerized Tomography to Measure the Accuracy of Total Knee Arthroplasty, (2003)

  • Henckel,
  • J.,
  • Richards,
  • R.,
  • Cobb,
  • J.P.,
  • ...

Third Annual Meeting of CAOS International, Marbella, Spain, 18-21 June,

The need for resources for clinical research: proceedings of a policy conference held at the European Heart House, 27-28 June 2002: executive summary (2003)

  • Bassand,
  • J.P.,
  • Martin,
  • J.,
  • Ryden,
  • L.,
  • ...

The medical profession, in particular cardiologists, acknowledge the fact that during the last 30 years, much of the progress made in the field of medicine has resulted from fruitful and close...

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. (2003)

  • Segurado,
  • R.,
  • Detera-Wadleigh,
  • S.D.,
  • Levinson,
  • D.F.,
  • ...

Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage. The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD genome scan data sets in an...

Organization on the plasma membrane of the retinitis pigmentosa protein RP2: investigation of association with detergent-resistant membranes and polarized sorting (2003)

  • Chapple,
  • J.P.,
  • Grayson,
  • C.,
  • Hardcastle,
  • A.J.,
  • ...

Mutations in the retinitis pigmentosa protein gene RP2 account for up to 15% of X-linked retinitis pigmentosa. RP2 is a novel protein of unknown function, which is targeted to the plasma membrane by...

Circulating endothelial progenitor cells, vascular function, and cardiovascular risk (2003)

  • Hill,
  • J.M.,
  • Zalos,
  • G.,
  • Halcox,
  • J.P.,
  • ...

BACKGROUND: Cardiovascular risk factors contribute to atherogenesis by inducing endothelial-cell injury and dysfunction. We hypothesized that endothelial progenitor cells derived from bone marrow...

High incidence of Kaposi sarcoma-associated herpesvirus-related non-Hodgkin lymphoma in patients with HIV infection and multicentric Castleman disease (2002)

  • Oksenhendler,
  • E.,
  • Boulanger,
  • E.,
  • Galicier,
  • L.,
  • ...

Multicentric Castleman disease (MCD) is a distinct type of lymphoproliferative disorder associated with inflammatory symptoms and interleukin 6 (IL-6) dysregulation. In the context of human...

The Leber congenital amaurosis gene product AIPL1 is localized exclusively in rod photoreceptors of the adult human retina (2002)

Leber congenital amaurosis (LCA) is the most severe inherited retinal dystrophy resulting in markedly impaired vision or blindness at birth. LCA is characterized by an extinguished electroretinogram...

Predisposition to atherosclerosis by infections: role of endothelial dysfunction (2002)

  • Prasad,
  • A.,
  • Zhu,
  • J.,
  • Halcox,
  • J.P.,
  • ...

BACKGROUND: Several microorganisms have been implicated in the pathogenesis of atherosclerosis. We hypothesized that infections may predispose to atherosclerosis by inflicting endothelial injury....

Prognostic value of coronary vascular endothelial dysfunction (2002)

  • Halcox,
  • J.P.,
  • Schenke,
  • W.H.,
  • Zalos,
  • G.,
  • ...

BACKGROUND: Whether patients at increased risk can be identified from a relatively low-risk population by coronary vascular function testing remains unknown. We investigated the relationship between...

Assembly limits the pharmacological complexity of ATP-sensitive potassium channels (2002)

  • Giblin,
  • J.P.,
  • Cui,
  • Y.,
  • Clapp,
  • L.H.,
  • ...

ATP-sensitive potassium channels (K(ATP) channels) are formed from an octameric complex of an inwardly rectifying K(+) channel (Kir6.1, Kir6.2) and a sulfonylurea receptor (SUR1, SUR2A, and SUR2B)....

Influence of age on CD4 cell recovery in human immunodeficiency virus- infected patients receiving highly active antiretroviral therapy: evidence from the EuroSIDA study (2001)

  • Viard,
  • J.P.,
  • Mocroft,
  • A.,
  • Chiesi,
  • A.,
  • ...

Influence of age on the CD4 cell response to highly active antiretroviral therapy (HAART) was examined in 1956 patients (median age, 37.2 years) in the EuroSIDA study. Median initial CD4 cell count...

Clinical outcome among HIV-infected patients starting saquinavir hard gel compared to ritonavir or indinavir (2001)

  • Kirk,
  • O.,
  • Mocroft,
  • A.,
  • Pradier,
  • C.,
  • ...

OBJECTIVE: To compare the clinical response among patients who initiate protease inhibitor therapies with different virological potency. DESIGN: We analysed patients who started indinavir, ritonavir...

Multiple groups of novel retroviral genomes in pigs and related species (2001)

  • Patience,
  • C.,
  • Switzer,
  • W.M.,
  • Takeuchi,
  • Y.,
  • ...

In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus...

Multiple groups of novel retroviral genomes in pigs and related species (2001)

  • Patience,
  • C.,
  • Switzer,
  • W.M.,
  • Takeuchi,
  • Y.,
  • ...

In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus...

Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G (2000)

  • Tkalcevic,
  • J.,
  • Novelli,
  • M.,
  • Phylactides,
  • M.,
  • ...

While the critical role of reactive oxygen intermediates (ROI) in the microbicidal activity of polymorphonuclear granulocytes is well established, the function of the nonoxidative effector mechanisms...

Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4 serotoninergic receptor could explain neonatal lupus congenital heart block (2000)

  • Eftekhari,
  • P.,
  • Salle,
  • L.,
  • Lezoualc'h,
  • F.,
  • ...

The 52-kDa SSA/Ro (Ro52) ribonucleoprotein is an antigenic target strongly associated with the autoimmune response in mothers whose children develop neonatal lupus and congenital heart block. When...

A conserved mechanism of retrovirus restriction in mammals (2000)

  • Towers,
  • G.,
  • Bock,
  • M.,
  • Martin,
  • S.,
  • ...

The murine Fv1 gene restricts infection

The small intestine can both absorb and glucuronidate luminal flavonoids (1999)

  • Spencer,
  • J.P.,
  • Chowrimootoo,
  • G.,
  • Choudhury,
  • R.,
  • ...

We have studied the perfusion of the jejunum and ileum in an isolated rat intestine model with flavonoids and hydroxycinnamates and the influence of glycosylation on the subsequent metabolism....

Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma (1999)

  • Dupin,
  • N.,
  • Fisher,
  • C.,
  • Kellam,
  • P.,
  • ...

Human herpesvirus 8 (HHV-8, also called KSHV) is linked to the etiopathogenesis of Kaposi's sarcoma (KS), multicentric Castleman's disease (MCD), and primary effusion lymphoma (PEL). The universal...

Advanced epithelial ovarian cancer: 1998 consensus statements (1999)

  • Berek,
  • J.S.,
  • Bertelsen,
  • K.,
  • DuBois,
  • A.,
  • ...

Background: During an international workshop held in September 1998, a group of specialists in the field of ovarian cancer reached consensus on a number of issues with implications for standard...

High resolution, multi-parameter quantitative MRI studies of rabbit corpus callosum at 7 T (1997)

Magn. Reson. Materials Phys. Med. Biol

A computer system for the interactive planning and prediction of maxillofacial surgery (1988)

A computer system has been developed for the simulation of facial surgery with interactive three-dimensional graphic techniques and data derived from computed tomographic scans and a purpose-built...

A computer system for the interactive planning and prediction of maxillofacial surgery (1988)

A computer system has been developed for the simulation of facial surgery with interactive three-dimensional graphic techniques and data derived from computed tomographic scans and a purpose-built...

A computer system for the interactive planning and prediction of maxillofacial surgery (1988)

A computer system has been developed for the simulation of facial surgery with interactive three-dimensional graphic techniques and data derived from computed tomographic scans and a purpose-built...

A chat about America. October and November, 1884. (1885)

"Printed for private circulation only."

 
Additional Information

Publishing period:

1873 - 2006 (177)

Co-authors: