Quezada, S.A., Peggs, K.S., Curran, M.A., Allison, J.P.
CTL-associated antigen 4 (CTLA4) blockade releases inhibitory controls on T cell activation and proliferation, inducing antitumor immunity in both preclinical and early clinical trials. We examined...
Activation and differentiation requirements of primary T cells in vitro.
Sagerström, C G, Kerr, E M, Allison, J P, Davis, M M
The progression of T cells from a quiescent or resting state to fully activated, proliferating cells is a crucial step in the initiation of an immune response. We have developed an in vitro system to...
Richie, E R, McEntire, B, Crispe, N, Kimura, J, Lanier, L L, Allison, J P
Alterations in gene expression that orchestrate eukaryotic cellular differentiation often require appropriate interactions between differentiating cells and a specialized microenvironment. During...
Havran, W L, Grell, S, Duwe, G, Kimura, J, Wilson, A, Kruisbeek, A M, ...
To study the origin of and the degree of T-cell antigen receptor (TCR) diversity of Thy-1+ dendritic epidermal cells (Thy-1+ dECs) in mice, we have developed a monoclonal antibody (mAb 536) to the...
Murine Ia and human DR antigens: homology of amino-terminal sequences.
Allison, J P, Walker, L E, Russell, W A, Pellegrino, M A, Ferrone, S, Reisfeld, R A, ...
Murine Ia and human DR antigens were isolated and purified by immunoprecipitation and sodium dodecyl sulfate/polyacrylamide gel electrophoresis with allo- and xenoantisera, respectively. The I-A...
Activation and differentiation requirements of primary T cells in vitro.
Sagerström, C G, Kerr, E M, Allison, J P, Davis, M M
The progression of T cells from a quiescent or resting state to fully activated, proliferating cells is a crucial step in the initiation of an immune response. We have developed an in vitro system to...
Richie, E R, McEntire, B, Crispe, N, Kimura, J, Lanier, L L, Allison, J P
Alterations in gene expression that orchestrate eukaryotic cellular differentiation often require appropriate interactions between differentiating cells and a specialized microenvironment. During...
Havran, W L, Grell, S, Duwe, G, Kimura, J, Wilson, A, Kruisbeek, A M, ...
To study the origin of and the degree of T-cell antigen receptor (TCR) diversity of Thy-1+ dendritic epidermal cells (Thy-1+ dECs) in mice, we have developed a monoclonal antibody (mAb 536) to the...
Murine Ia and human DR antigens: homology of amino-terminal sequences.
Allison, J P, Walker, L E, Russell, W A, Pellegrino, M A, Ferrone, S, Reisfeld, R A, ...
Murine Ia and human DR antigens were isolated and purified by immunoprecipitation and sodium dodecyl sulfate/polyacrylamide gel electrophoresis with allo- and xenoantisera, respectively. The I-A...