J. P. Aubert

Publication List Details

Period

1982 - 2006

Number

48

Co-Authors

Topological Semantic for Hybrid Modal Logic and Spatial Logic (2006)

Aubert, J.P.

Topological Semantic for Hybrid Modal Logic and Spatial Logic

Topological Semantic for Hybrid Modal Logic and Spatial Logic (2006)

Aubert, J.P.

Topological Semantic for Hybrid Modal Logic and Spatial Logic

Topological Semantic for Hybrid Modal Logic and Spatial Logic (2006)

Aubert, J.P.

Topological Semantic for Hybrid Modal Logic and Spatial Logic

Abnormalities in mucin gene expression in Crohn's disease (1999)

Desreumaux, P, Debailleul, V, Gambiez, L, Geboes, K, ...

Alterations in the structure and/or quantity of mucins could alter the barrier function of mucus and play a role in initiating and maintaining mucosal inflammation in Crohn's disease. To investigate...

Organization of a Clostridium thermocellum gene cluster encoding the cellulosomal scaffolding protein CipA and a protein possibly involved in attachment of the cellulosome to the cell surface.

Fujino, T, Béguin, P, Aubert, J P

The nucleotide sequence was determined for a 9.4-kb region of Clostridium thermocellum DNA extending from the 3' end of the gene (now termed cipA), encoding the S1/SL component of the cellulosome....

Recognition specificity of the duplicated segments present in Clostridium thermocellum endoglucanase CelD and in the cellulosome-integrating protein CipA.

Salamitou, S, Raynaud, O, Lemaire, M, Coughlan, M, Béguin, P, Aubert, J P

The binding specificity of the duplicated segments borne by Clostridium thermocellum endoglucanase CelD and by the cellulosome-integrating protein CipA was investigated. The fusion protein...

Subcellular localization of Clostridium thermocellum ORF3p, a protein carrying a receptor for the docking sequence borne by the catalytic components of the cellulosome.

Salamitou, S, Lemaire, M, Fujino, T, Ohayon, H, Gounon, P, Béguin, P, ...

The ORF3 gene of Clostridium thermocellum encodes a polypeptide (ORF3p) which contains a receptor domain for the docking sequence borne by the catalytic subunits of the cellulosome and a triplicated...

Transcription of Clostridium thermocellum endoglucanase genes celF and celD.

Mishra, S, Béguin, P, Aubert, J P

Transcripts of the Clostridium thermocellum endoglucanase genes celF and celD, encoding endoglucanases F and D, respectively, were characterized. The size of the mRNAs was about 2.35 kb for celF and...

Purification and characterization of glutamine synthetase from the archaebacterium Methanobacterium ivanovi.

Bhatnagar, L, Zeikus, J G, Aubert, J P

Glutamine synthetase (GS) was purified to electrophoretic homogeneity from the obligate anaerobic archaebacterium Methanobacterium ivanovi. The 130-fold-purified enzyme was obtained by heat...

Sequence of a cellulase gene of the thermophilic bacterium Clostridium thermocellum.

Béguin, P, Cornet, P, Aubert, J P

The nucleotide sequence of the celA gene, encoding the extracellular endoglucanase A of Clostridium thermocellum, was determined and compared with the NH2-terminal amino acid sequence of the purified...

Nucleotide sequence of the cellulase gene celD encoding endoglucanase D of Clostridium thermocellum.

Joliff, G, Béguin, P, Aubert, J P

The nucleotide sequence of the celD gene, encoding the previously crystallized endoglucanase D of Clostridium thermocellum, is reported. The enzyme shares a conserved, reiterated domain with the...

Interaction between secretory leucocyte proteinase inhibitor and bronchial mucins or glycopeptides. Physiopathological implications for the protection of mucins against proteolysis by human leucocyte elastase.

Van-Seuningen, I, Aubert, J P, Davril, M

The interaction of secretory leucocyte proteinase inhibitor with bronchial mucins and glycopeptides was studied by means of c.d. spectroscopy. The interaction with mucins was characterized by an...

Degenerate 87-base-pair tandem repeats create hydrophilic/hydrophobic alternating domains in human mucin peptides mapped to 11p15.

Dufosse, J, Porchet, N, Audie, J P, Guyonnet Duperat, V, Laine, A, Van-Seuningen, I, ...

A human tracheobronchial lambda gt 11 cDNA library was screened using antiserum prepared against the deglycosylated protein backbone of human tracheobronchial mucins. Two cDNAs, designated JER 28 and...

Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes?

Guyonnet Duperat, V, Audie, J P, Debailleul, V, Laine, A, Buisine, M P, Galiegue-Zouitina, S, ...

To date five human mucin cDNAs (MUC2, 5A, 5B, 5C and 6) mapped to 11p15.3-15.5, so it appears that this chromosome region might contain several distinct gene loci for mucins. Three of these cDNAs,...

Calcium-binding affinity and calcium-enhanced activity of Clostridium thermocellum endoglucanase D.

Chauvaux, S, Beguin, P, Aubert, J P, Bhat, K M, Gow, L A, Wood, T M, ...

Clostridium thermocellum endoglucanase D (EC 3.2.1.4: EGD), which is encoded by the celD gene, was found to bind Ca2+ with an association constant of 2.03 x 10(6) M-1. Ca2+ stimulated the activity of...

Evidence for interactions between the 30 kDa N- and 50 kDa C-terminal tryptic fragments of human lactotransferrin.

Legrand, D, Mazurier, J, Aubert, J P, Loucheux-Lefebvre, M H, Montreuil, J, Spik, G

Gel filtration of a mild tryptic digest of diferric human lactotransferrin carried out in presence of 10% (v/v) acetic acid led to the isolation of two fragments, an N-terminal tryptic fragment...

Genomic organization of the 3'-region of the human MUC5AC mucin gene: additional evidence for a common ancestral gene for the 11p15.5 mucin gene family.

Buisine, M P, Desseyn, J L, Porchet, N, Degand, P, Laine, A, Aubert, J P

The human mucin gene MUC5AC is mapped clustered with MUC2, MUC5B and MUC6 on chromosome 11p15.5. We report here the isolation and characterization of a genomic cosmid clone, designated ELO9, spanning...

Human mucin gene MUC4: organization of its 5'-region and polymorphism of its central tandem repeat array.

Nollet, S, Moniaux, N, Maury, J, Petitprez, D, Degand, P, Laine, A, ...

In a previous study we isolated a partial cDNA with a tandem repeat of 48 bp, which allowed us to map a novel human mucin gene named MUC4 to chromosome 3q29. Here we report the organization and...

Permanent exposure of mucin-secreting HT-29 cells to benzyl-N-acetyl-alpha-D-galactosaminide induces abnormal O-glycosylation of mucins and inhibits constitutive and stimulated MUC5AC secretion.

Hennebicq-Reig, S, Lesuffleur, T, Capon, C, De Bolos, C, Kim, I, Moreau, O, ...

Previous work has shown that treatment of HT-29 methotrexate (MTX) cells with benzyl-N-acetyl-alpha-D-galactosaminide results in profound changes in mucin oligosaccharide chains. To analyse in depth...

Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin.

Moniaux, N, Nollet, S, Porchet, N, Degand, P, Laine, A, Aubert, J P

The MUC4 gene, which encodes a human epithelial mucin, is expressed in various epithelial tissues, just as well in adult as in poorly differentiated cells in the embryo and fetus. Its N-terminus and...

Sequence of the 5'-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells.

Van Seuningen, I, Perrais, M, Pigny, P, Porchet, N, Aubert, J P

Control of gene expression in intestinal cells is poorly understood. Molecular mechanisms that regulate transcription of cellular genes are the foundation for understanding developmental and...

Human mucin gene MUC5AC: organization of its 5'-region and central repetitive region.

Escande, F, Aubert, J P, Porchet, N, Buisine, M P

Human mucin gene MUC5AC is clustered with MUC2, MUC5B and MUC6 on chromosome 11p15.5. We report here the full length cDNA sequence upstream of the repetitive region of human MUC5AC. We have also...

Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disorders.

Giraud, S, Zhang, C X, Serova-Sinilnikova, O, Wautot, V, Salandre, J, Buisson, N, ...

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome predisposing to tumors of the parathyroid, endocrine pancreas, anterior pituitary, adrenal glands, and diffuse...

Prediction of the conformation of the cow and sheep kappa-caseins.

Loucheux-Lefebvre, M H, Aubert, J P, Jollès, P

The secondary structures of cow and sheep kappa-caseins were established according to the predictive rules of Chou and Fasman. The diagrams derived from this treatment allowed us to study the...

Organization of a Clostridium thermocellum gene cluster encoding the cellulosomal scaffolding protein CipA and a protein possibly involved in attachment of the cellulosome to the cell surface.

Fujino, T, Béguin, P, Aubert, J P

The nucleotide sequence was determined for a 9.4-kb region of Clostridium thermocellum DNA extending from the 3' end of the gene (now termed cipA), encoding the S1/SL component of the cellulosome....

Recognition specificity of the duplicated segments present in Clostridium thermocellum endoglucanase CelD and in the cellulosome-integrating protein CipA.

Salamitou, S, Raynaud, O, Lemaire, M, Coughlan, M, Béguin, P, Aubert, J P

The binding specificity of the duplicated segments borne by Clostridium thermocellum endoglucanase CelD and by the cellulosome-integrating protein CipA was investigated. The fusion protein...

Subcellular localization of Clostridium thermocellum ORF3p, a protein carrying a receptor for the docking sequence borne by the catalytic components of the cellulosome.

Salamitou, S, Lemaire, M, Fujino, T, Ohayon, H, Gounon, P, Béguin, P, ...

The ORF3 gene of Clostridium thermocellum encodes a polypeptide (ORF3p) which contains a receptor domain for the docking sequence borne by the catalytic subunits of the cellulosome and a triplicated...

Transcription of Clostridium thermocellum endoglucanase genes celF and celD.

Mishra, S, Béguin, P, Aubert, J P

Transcripts of the Clostridium thermocellum endoglucanase genes celF and celD, encoding endoglucanases F and D, respectively, were characterized. The size of the mRNAs was about 2.35 kb for celF and...

Purification and characterization of glutamine synthetase from the archaebacterium Methanobacterium ivanovi.

Bhatnagar, L, Zeikus, J G, Aubert, J P

Glutamine synthetase (GS) was purified to electrophoretic homogeneity from the obligate anaerobic archaebacterium Methanobacterium ivanovi. The 130-fold-purified enzyme was obtained by heat...

Sequence of a cellulase gene of the thermophilic bacterium Clostridium thermocellum.

Béguin, P, Cornet, P, Aubert, J P

The nucleotide sequence of the celA gene, encoding the extracellular endoglucanase A of Clostridium thermocellum, was determined and compared with the NH2-terminal amino acid sequence of the purified...

Nucleotide sequence of the cellulase gene celD encoding endoglucanase D of Clostridium thermocellum.

Joliff, G, Béguin, P, Aubert, J P

The nucleotide sequence of the celD gene, encoding the previously crystallized endoglucanase D of Clostridium thermocellum, is reported. The enzyme shares a conserved, reiterated domain with the...

Interaction between secretory leucocyte proteinase inhibitor and bronchial mucins or glycopeptides. Physiopathological implications for the protection of mucins against proteolysis by human leucocyte elastase.

Van-Seuningen, I, Aubert, J P, Davril, M

The interaction of secretory leucocyte proteinase inhibitor with bronchial mucins and glycopeptides was studied by means of c.d. spectroscopy. The interaction with mucins was characterized by an...

Degenerate 87-base-pair tandem repeats create hydrophilic/hydrophobic alternating domains in human mucin peptides mapped to 11p15.

Dufosse, J, Porchet, N, Audie, J P, Guyonnet Duperat, V, Laine, A, Van-Seuningen, I, ...

A human tracheobronchial lambda gt 11 cDNA library was screened using antiserum prepared against the deglycosylated protein backbone of human tracheobronchial mucins. Two cDNAs, designated JER 28 and...

Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes?

Guyonnet Duperat, V, Audie, J P, Debailleul, V, Laine, A, Buisine, M P, Galiegue-Zouitina, S, ...

To date five human mucin cDNAs (MUC2, 5A, 5B, 5C and 6) mapped to 11p15.3-15.5, so it appears that this chromosome region might contain several distinct gene loci for mucins. Three of these cDNAs,...

Calcium-binding affinity and calcium-enhanced activity of Clostridium thermocellum endoglucanase D.

Chauvaux, S, Beguin, P, Aubert, J P, Bhat, K M, Gow, L A, Wood, T M, ...

Clostridium thermocellum endoglucanase D (EC 3.2.1.4: EGD), which is encoded by the celD gene, was found to bind Ca2+ with an association constant of 2.03 x 10(6) M-1. Ca2+ stimulated the activity of...

Evidence for interactions between the 30 kDa N- and 50 kDa C-terminal tryptic fragments of human lactotransferrin.

Legrand, D, Mazurier, J, Aubert, J P, Loucheux-Lefebvre, M H, Montreuil, J, Spik, G

Gel filtration of a mild tryptic digest of diferric human lactotransferrin carried out in presence of 10% (v/v) acetic acid led to the isolation of two fragments, an N-terminal tryptic fragment...

Genomic organization of the 3'-region of the human MUC5AC mucin gene: additional evidence for a common ancestral gene for the 11p15.5 mucin gene family.

Buisine, M P, Desseyn, J L, Porchet, N, Degand, P, Laine, A, Aubert, J P

The human mucin gene MUC5AC is mapped clustered with MUC2, MUC5B and MUC6 on chromosome 11p15.5. We report here the isolation and characterization of a genomic cosmid clone, designated ELO9, spanning...

Human mucin gene MUC4: organization of its 5'-region and polymorphism of its central tandem repeat array.

Nollet, S, Moniaux, N, Maury, J, Petitprez, D, Degand, P, Laine, A, ...

In a previous study we isolated a partial cDNA with a tandem repeat of 48 bp, which allowed us to map a novel human mucin gene named MUC4 to chromosome 3q29. Here we report the organization and...

Permanent exposure of mucin-secreting HT-29 cells to benzyl-N-acetyl-alpha-D-galactosaminide induces abnormal O-glycosylation of mucins and inhibits constitutive and stimulated MUC5AC secretion.

Hennebicq-Reig, S, Lesuffleur, T, Capon, C, De Bolos, C, Kim, I, Moreau, O, ...

Previous work has shown that treatment of HT-29 methotrexate (MTX) cells with benzyl-N-acetyl-alpha-D-galactosaminide results in profound changes in mucin oligosaccharide chains. To analyse in depth...

Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin.

Moniaux, N, Nollet, S, Porchet, N, Degand, P, Laine, A, Aubert, J P

The MUC4 gene, which encodes a human epithelial mucin, is expressed in various epithelial tissues, just as well in adult as in poorly differentiated cells in the embryo and fetus. Its N-terminus and...

Sequence of the 5'-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells.

Van Seuningen, I, Perrais, M, Pigny, P, Porchet, N, Aubert, J P

Control of gene expression in intestinal cells is poorly understood. Molecular mechanisms that regulate transcription of cellular genes are the foundation for understanding developmental and...

Human mucin gene MUC5AC: organization of its 5'-region and central repetitive region.

Escande, F, Aubert, J P, Porchet, N, Buisine, M P

Human mucin gene MUC5AC is clustered with MUC2, MUC5B and MUC6 on chromosome 11p15.5. We report here the full length cDNA sequence upstream of the repetitive region of human MUC5AC. We have also...

Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disorders.

Giraud, S, Zhang, C X, Serova-Sinilnikova, O, Wautot, V, Salandre, J, Buisson, N, ...

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome predisposing to tumors of the parathyroid, endocrine pancreas, anterior pituitary, adrenal glands, and diffuse...

Prediction of the conformation of the cow and sheep kappa-caseins.

Loucheux-Lefebvre, M H, Aubert, J P, Jollès, P

The secondary structures of cow and sheep kappa-caseins were established according to the predictive rules of Chou and Fasman. The diagrams derived from this treatment allowed us to study the...