J. P. Dougherty

Publication List Details

Period

1998 - 2005

Number

44

Co-Authors

A THEORY OF INCOHERENT SCATTERING OF RADIO WAVES BY A PLASMA IN A UNIFORM MAGNETIC FIELD (2005)

FARLEY,D.T., DOUGHERTY,J.P., BARRON,D.W.

A general expression for the frequency spectrum of radio waves scattered by the random thermal fluctuations of electron density in a plasma in thermal equilibrium and in a magnetic field is derived....

Development and Verification of Pyroelectric Materials with Low Thermal Diffusivity. (2002)

Loiacono,G. M., Dougherty,J. P.

The growth of TGS, DTGS, TGFB and DTGFB crystals from solutions containing Cd, Zn, Cu and Pd impurities (5 mole % level) has resulted in improved properties of these pyroelectric materials....

Piezoelectric and Electrostrictive Materials for Transducer Applications. Volume 1. (1998)

Cross, L. E., Newnham, R. E., Bhalla, A. S., Dougherty, J. P., Adair, J. H.

Studies of the 3:0 type composite have evolved a new structure for a much more effective stress transforming composite. The device uses cavities in the electrode structure which are simple,...

Piezoelectric and Electrostrictive Materials for Transducer Applications. Volume 2. (1998)

Cross, L. E., Newnham, R. E., Bhalla, A. S., Dougherty, J. P., Adair, J. H.

Contents: Thermodynamic Theory of PbZrO3; Thermodynamic Theory of the Lead Zirconate-Titanate Solid Solution System; Part I. Phenomenlogy; Part II. Tricritical Behavior; Part III. Curie Constant and...

Piezoelectric and Electrostrictive Materials for Transducer Applications. Volume 1. (1998)

Cross, L. E., Newnham, R. E., Bhalla, A. S., Dougherty, J. P., Adair, J. H.

Highlights of the year's activity include: Participation of a number of senior faculty in program to better define the role of ferroelectrics in 'smart materials' and the manner in which these...

Piezoelectric and Electrostrictive Materials for Transducer Applications. Volume 2. (1998)

Cross, L. E., Newnham, R. E., Bhalla, A. S., Dougherty, J. P., Adair, J. H.

This report documents work carried out on piezoelectric and electrostrictive materials for transducer applications. It discusses the role of ferroelectrics in smart materials and the manner in which...

Piezoelectric and Electrostrictive Materials for Transducers Applications. Volume 1. (1998)

Cross, L. E., Newnham, R. E., Bhalla, A. S., Dougherty, J. P., Adair, J. H.

Highlights of the past year's activities include: An increased emphasis upon the flextensional (moonie) type actuators, modeling both the internal stress distribution as a function of geometry, and...

Piezoelectric and Electrostrictive Materials for Transducers Applications. Volume 2. (1998)

Cross, L. E., Newnham, R. E., Bhalla, A. S., Dougherty, J. P., Adair, J. H.

Table Of Contents: Ceramic-Metal Composite Actuator; Effects of Surface Layers on the Physical Properties of Lanthanum Doped Lead Zirconate Titanate Ceramic; The Influence of Surface Contamination on...

Piezoelectric and Electrostrictive Materials for Transducers Applications. Volume 3. (1998)

Cross, L. E., Newnham, R. E., Bhalla, A. S., Dougherty, J. P., Adair, J. H.

Contents: Distribution Functions of Coexisting Phases in a Complete Solid Solution System; The Glassy Behaviour of Relaxor Ferroelectrics; The Dielectric Relaxation of Lead Magnesium Niobate Relaxor...

Piezoelectric and Electrostrictive Materials for Transducers Applications. Volume 4. (1998)

Cross, L. E., Newnham, R. E., Bhalla, A. S., Dougherty, J. P., Adair, J. H.

Table Of Contents: A Study of Y1Ba2Cu3O7-x Thick Films on Ferroelectric Substrates; Y1Ba2Cu307-X As An Electrode Materials for Ferroelectric Devices; Polarization Reversal and High Dielectric...

Particle and Grain Size Effects on the Dielectric Behavior of the Relaxor Ferroelectric PbMg(1/3)Nb(2/3)O3. (1998)

Papet, P., Dougherty, J. P., Shrout, T. R.

The role of particle and grain size on the dielectric behavior of the perovskite relaxor ferroelectric Pb(Mg(1/3)Nb(2/3))O3 (PMN) was investigated. Ultrafine powders of PMN were prepared using a...

Excimer Laser Ablated Lead Zirconate Titanate Thin Films. (1998)

Roy, D., Krupanidhi, S. B., Dougherty, J. P.

Lead zirconate titanate (PZT) thin films on platinum coated silicon were prepared by excimer laser ablation and crystallized by subsequent annealing. Crystalline perovskite PZT films showed a...

A murine model for B-lymphocyte somatic cell gene therapy.

Sutkowski, N, Kuo, M L, Varela-Echavarria, A, Dougherty, J P, Ron, Y

Mature primary B lymphocytes represent a potentially important cellular target for somatic cell gene therapy, which could prove advantageous for the treatment of certain metabolic and immunologic...

Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications.

Parthasarathi, S, Varela-Echavarría, A, Ron, Y, Preston, B D, Dougherty, J P

Retroviruses evolve at rapid rates, which is presumably advantageous for responding to selective pressures. Understanding the basic mutational processes involved during retroviral replication is...

Inducible human immunodeficiency virus type 1 packaging cell lines.

Yu, H, Rabson, A B, Kaul, M, Ron, Y, Dougherty, J P

Packaging cell lines are important tools for transferring genes into eukaryotic cells. Human immunodeficiency virus type 1 (HIV-1)-based packaging cell lines are difficult to obtain, in part owing to...

Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free system.

Klarmann, G J, Yu, H, Chen, X, Dougherty, J P, Preston, B D

Human immunodeficiency virus type 1 (HIV-1) replication requires conversion of viral RNA to double-stranded DNA. To better understand the molecular mechanisms of this process, we examined viral DNA...

High rate of genetic rearrangement during replication of a Moloney murine leukemia virus-based vector.

Varela-Echavarría, A, Prorock, C M, Ron, Y, Dougherty, J P

A protocol was designed to measure the forward mutation rate over an entire gene replicated as part of a Moloney murine leukemia virus-based vector. For these studies, the herpes simplex virus...

Reticuloendotheliosis type C and primate type D oncoretroviruses are members of the same receptor interference group.

Koo, H M, Gu, J, Varela-Echavarria, A, Ron, Y, Dougherty, J P

The reticuloendotheliosis viruses (REVs), originally isolated from avian species, constitute a group of retroviruses which are more closely related to mammalian retroviruses than to other avian...

Spleen necrosis virus, an avian retrovirus, can infect primate cells.

Koo, H M, Brown, A M, Ron, Y, Dougherty, J P

Spleen necrosis virus (SNV) is an avian retrovirus that can infect some mammalian cells such as dog cells as well as all avian cells tested to date. We were interested in testing whether SNV could...

New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors.

Dougherty, J P, Wisniewski, R, Yang, S L, Rhode, B W, Temin, H M

We prepared retrovirus packaging cell lines containing gag-pol genes from spleen necrosis virus (expressed from a cytomegalovirus promoter and the simian virus 40 (SV40) polyadenylation sequences)...

Determination of the rate of base-pair substitution and insertion mutations in retrovirus replication.

Dougherty, J P, Temin, H M

We recently described a protocol for determination of retrovirus mutation rates, that is, the mutation frequency in a single cycle of retrovirus replication (J.P. Dougherty and H.M. Temin, Mol. Cell....

A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing.

Dougherty, J P, Temin, H M

We constructed a retrovirus vector in which all viral transcriptional signals are deleted during provirus formation. This vector would be safer and more useful in gene-transfer experiments....

The thermal stability of oligonucleotide duplexes is sequence independent in tetraalkylammonium salt solutions: application to identifying recombinant DNA clones.

Jacobs, K A, Rudersdorf, R, Neill, S D, Dougherty, J P, Brown, E L, Fritsch, E F

In solutions of tetraalkylammonium salts the melting temperature of oligonucleotide duplexes is independent of nucleotide sequence and thus GC content. Data quantitating the destabilizing effects of...

Immobilization of DNA via oligonucleotides containing an aldehyde or carboxylic acid group at the 5' terminus.

Kremsky, J N, Wooters, J L, Dougherty, J P, Meyers, R E, Collins, M, Brown, E L

A general method for the immobilization of DNA through its 5'-end has been developed. A synthetic oligonucleotide, modified at its 5'-end with an aldehyde or carboxylic acid, was attached to latex...

Rapid hybridization kinetics of DNA attached to submicron latex particles.

Wolf, S F, Haines, L, Fisch, J, Kremsky, J N, Dougherty, J P, Jacobs, K

We describe a novel method for attaching any DNA molecule to submicron latex beads and characterize the hybridization kinetic properties of these bead-DNA conjugates. The conjugates hybridize to DNA...

Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer.

Sassone-Corsi, P, Dougherty, J P, Wasylyk, B, Chambon, P

Insertion of the simian virus 40 enhancer upstream from the +33 to -34 adenovirus major late promoter element or the +62 to -102 conalbumin promoter region causes a 10-fold stimulation of specific...

The mouse immunoglobulin heavy-chain gene enhancer contains sequences that inhibit transcription in vitro in HeLa cell extracts.

Dougherty, J P, Augereau, P, Chambon, P

The effect of the cell-specific mouse immunoglobulin heavy-chain gene (IgH) enhancer on transcription from heterologous promoter elements was studied in vitro with a HeLa whole-cell extract. No...

High mutation rate of a spleen necrosis virus-based retrovirus vector.

Dougherty, J P, Temin, H M

Spleen necrosis virus (SNV) is an avian retrovirus that efficiently infects some mammalian cells (e.g., dog and rat cells). We constructed an SNV-based vector, which contains less than 1 kilobase...

A murine model for B-lymphocyte somatic cell gene therapy.

Sutkowski, N, Kuo, M L, Varela-Echavarria, A, Dougherty, J P, Ron, Y

Mature primary B lymphocytes represent a potentially important cellular target for somatic cell gene therapy, which could prove advantageous for the treatment of certain metabolic and immunologic...

Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications.

Parthasarathi, S, Varela-Echavarría, A, Ron, Y, Preston, B D, Dougherty, J P

Retroviruses evolve at rapid rates, which is presumably advantageous for responding to selective pressures. Understanding the basic mutational processes involved during retroviral replication is...

Inducible human immunodeficiency virus type 1 packaging cell lines.

Yu, H, Rabson, A B, Kaul, M, Ron, Y, Dougherty, J P

Packaging cell lines are important tools for transferring genes into eukaryotic cells. Human immunodeficiency virus type 1 (HIV-1)-based packaging cell lines are difficult to obtain, in part owing to...

Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free system.

Klarmann, G J, Yu, H, Chen, X, Dougherty, J P, Preston, B D

Human immunodeficiency virus type 1 (HIV-1) replication requires conversion of viral RNA to double-stranded DNA. To better understand the molecular mechanisms of this process, we examined viral DNA...

High rate of genetic rearrangement during replication of a Moloney murine leukemia virus-based vector.

Varela-Echavarría, A, Prorock, C M, Ron, Y, Dougherty, J P

A protocol was designed to measure the forward mutation rate over an entire gene replicated as part of a Moloney murine leukemia virus-based vector. For these studies, the herpes simplex virus...

Reticuloendotheliosis type C and primate type D oncoretroviruses are members of the same receptor interference group.

Koo, H M, Gu, J, Varela-Echavarria, A, Ron, Y, Dougherty, J P

The reticuloendotheliosis viruses (REVs), originally isolated from avian species, constitute a group of retroviruses which are more closely related to mammalian retroviruses than to other avian...

Spleen necrosis virus, an avian retrovirus, can infect primate cells.

Koo, H M, Brown, A M, Ron, Y, Dougherty, J P

Spleen necrosis virus (SNV) is an avian retrovirus that can infect some mammalian cells such as dog cells as well as all avian cells tested to date. We were interested in testing whether SNV could...

New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors.

Dougherty, J P, Wisniewski, R, Yang, S L, Rhode, B W, Temin, H M

We prepared retrovirus packaging cell lines containing gag-pol genes from spleen necrosis virus (expressed from a cytomegalovirus promoter and the simian virus 40 (SV40) polyadenylation sequences)...

Determination of the rate of base-pair substitution and insertion mutations in retrovirus replication.

Dougherty, J P, Temin, H M

We recently described a protocol for determination of retrovirus mutation rates, that is, the mutation frequency in a single cycle of retrovirus replication (J.P. Dougherty and H.M. Temin, Mol. Cell....

A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing.

Dougherty, J P, Temin, H M

We constructed a retrovirus vector in which all viral transcriptional signals are deleted during provirus formation. This vector would be safer and more useful in gene-transfer experiments....

The thermal stability of oligonucleotide duplexes is sequence independent in tetraalkylammonium salt solutions: application to identifying recombinant DNA clones.

Jacobs, K A, Rudersdorf, R, Neill, S D, Dougherty, J P, Brown, E L, Fritsch, E F

In solutions of tetraalkylammonium salts the melting temperature of oligonucleotide duplexes is independent of nucleotide sequence and thus GC content. Data quantitating the destabilizing effects of...

Immobilization of DNA via oligonucleotides containing an aldehyde or carboxylic acid group at the 5' terminus.

Kremsky, J N, Wooters, J L, Dougherty, J P, Meyers, R E, Collins, M, Brown, E L

A general method for the immobilization of DNA through its 5'-end has been developed. A synthetic oligonucleotide, modified at its 5'-end with an aldehyde or carboxylic acid, was attached to latex...

Rapid hybridization kinetics of DNA attached to submicron latex particles.

Wolf, S F, Haines, L, Fisch, J, Kremsky, J N, Dougherty, J P, Jacobs, K

We describe a novel method for attaching any DNA molecule to submicron latex beads and characterize the hybridization kinetic properties of these bead-DNA conjugates. The conjugates hybridize to DNA...

Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer.

Sassone-Corsi, P, Dougherty, J P, Wasylyk, B, Chambon, P

Insertion of the simian virus 40 enhancer upstream from the +33 to -34 adenovirus major late promoter element or the +62 to -102 conalbumin promoter region causes a 10-fold stimulation of specific...

The mouse immunoglobulin heavy-chain gene enhancer contains sequences that inhibit transcription in vitro in HeLa cell extracts.

Dougherty, J P, Augereau, P, Chambon, P

The effect of the cell-specific mouse immunoglobulin heavy-chain gene (IgH) enhancer on transcription from heterologous promoter elements was studied in vitro with a HeLa whole-cell extract. No...

High mutation rate of a spleen necrosis virus-based retrovirus vector.

Dougherty, J P, Temin, H M

Spleen necrosis virus (SNV) is an avian retrovirus that efficiently infects some mammalian cells (e.g., dog and rat cells). We constructed an SNV-based vector, which contains less than 1 kilobase...