Conservation and function of the transcriptional regulatory protein Runt.
A phylogenetic approach was used to identify conserved regions of the transcriptional regulator Runt. Alignment of the deduced protein sequences from Drosophila melanogaster, Drosophila...
Golling, G, Li, L, Pepling, M, Stebbins, M, Gergen, J P
The Drosophila runt gene is the founding member of the Runt domain family of transcriptional regulators. Mammalian Runt domain genes encode the alpha subunit of the heterometric DNA-binding factor...
Groucho-dependent and -independent repression activities of Runt domain proteins.
Aronson, B D, Fisher, A L, Blechman, K, Caudy, M, Gergen, J P
Runt domain proteins are transcriptional regulators that specify cell fates for processes extending from pattern formation in insects to leukemogenesis in humans. Runt domain family members are...
The initiator tRNA genes of Drosophila melanogaster: evidence for a tRNA pseudogene.
Sharp, S, DeFranco, D, Silberklang, M, Hosbach, H A, Schmidt, T, Kubli, E, ...
We have isolated four segments of Drosophila melanogaster DNA that hybridize to homologous initiator tRNAMet. Three of the cloned fragments contain initiator tRNA genes, each of which can be...
Filter replicas and permanent collections of recombinant DNA plasmids.
Gergen, J P, Stern, R H, Wensink, P C
A permanent, ordered collection of 23,000 recombinant DNA plasmids containing Drosophila melanogaster DNA has been established. Simple and practical methods for storing and manipulating this...
Dosage-Sensitive Maternal Modifiers of the Drosophila Segmentation Gene Runt
Duffy, J. B., Wells, J., Gergen, J. P.
The protein encoded by the pair-rule gene runt functions as a transcriptional regulator during anterior-posterior patterning of the Drosophila embryo. Results of over-expression experiments as well...
Mapping of Drosophila mutations using site-specific male recombination.
Chen, B, Chu, T, Harms, E, Gergen, J P, Strickland, S
Although recombination does not usually occur in the male Drosophila germline, site-specific recombination can be induced at the ends of P elements. This finding suggested that male recombination...
Quantitative analysis of gene function in the Drosophila embryo.
Tracey, W D, Ning, X, Klingler, M, Kramer, S G, Gergen, J P
The specific functions of gene products frequently depend on the developmental context in which they are expressed. Thus, studies on gene function will benefit from systems that allow for...
Conservation and function of the transcriptional regulatory protein Runt.
A phylogenetic approach was used to identify conserved regions of the transcriptional regulator Runt. Alignment of the deduced protein sequences from Drosophila melanogaster, Drosophila...
Golling, G, Li, L, Pepling, M, Stebbins, M, Gergen, J P
The Drosophila runt gene is the founding member of the Runt domain family of transcriptional regulators. Mammalian Runt domain genes encode the alpha subunit of the heterometric DNA-binding factor...
Groucho-dependent and -independent repression activities of Runt domain proteins.
Aronson, B D, Fisher, A L, Blechman, K, Caudy, M, Gergen, J P
Runt domain proteins are transcriptional regulators that specify cell fates for processes extending from pattern formation in insects to leukemogenesis in humans. Runt domain family members are...
The initiator tRNA genes of Drosophila melanogaster: evidence for a tRNA pseudogene.
Sharp, S, DeFranco, D, Silberklang, M, Hosbach, H A, Schmidt, T, Kubli, E, ...
We have isolated four segments of Drosophila melanogaster DNA that hybridize to homologous initiator tRNAMet. Three of the cloned fragments contain initiator tRNA genes, each of which can be...
Filter replicas and permanent collections of recombinant DNA plasmids.
Gergen, J P, Stern, R H, Wensink, P C
A permanent, ordered collection of 23,000 recombinant DNA plasmids containing Drosophila melanogaster DNA has been established. Simple and practical methods for storing and manipulating this...
Dosage-Sensitive Maternal Modifiers of the Drosophila Segmentation Gene Runt
Duffy, J. B., Wells, J., Gergen, J. P.
The protein encoded by the pair-rule gene runt functions as a transcriptional regulator during anterior-posterior patterning of the Drosophila embryo. Results of over-expression experiments as well...
Mapping of Drosophila mutations using site-specific male recombination.
Chen, B, Chu, T, Harms, E, Gergen, J P, Strickland, S
Although recombination does not usually occur in the male Drosophila germline, site-specific recombination can be induced at the ends of P elements. This finding suggested that male recombination...
Quantitative analysis of gene function in the Drosophila embryo.
Tracey, W D, Ning, X, Klingler, M, Kramer, S G, Gergen, J P
The specific functions of gene products frequently depend on the developmental context in which they are expressed. Thus, studies on gene function will benefit from systems that allow for...