ATA box transcription mutation in beta-thalassemia.
Orkin, S H, Sexton, J P, Cheng, T C, Goff, S C, Giardina, P J, Lee, J I, ...
DNA sequence analysis of a cloned beta-globin gene from a Chinese patient with beta-thalassemia revealed a single nucleotide substitution (A leads to G) within the ATA box homology and 28 base pairs...
beta-Thalassemia in American Blacks: novel mutations in the "TATA" box and an acceptor splice site.
Antonarakis, S E, Irkin, S H, Cheng, T C, Scott, A F, Sexton, J P, Trusko, S P, ...
beta-Thalassemia genes, although often mild in their effects, are common among American Blacks. We have begun a systematic molecular analysis of beta-thalassemia mutations in this group. DNA...
Cheng, T C, Orkin, S H, Antonarakis, S E, Potter, M J, Sexton, J P, Markham, A F, ...
To perform a systematic analysis of beta-thalassemia genes among Chinese, we have determined the DNA haplotype in the beta-globin gene region of 37 Chinese beta-thalassemia chromosomes. Only four...
Evidence for multiple origins of the beta E-globin gene in Southeast Asia.
Antonarakis, S E, Orkin, S H, Kazazian, H H, Goff, S C, Boehm, C D, Waber, P G, ...
To investigate whether recurrent mutation has contributed to the high frequency of the beta E-globin gene in Southeast Asia, we used the haplotypes at three polymorphic restriction sites within and...
Molecular characterization of seven beta-thalassemia mutations in Asian Indians.
Kazazian, H H, Orkin, S H, Antonarakis, S E, Sexton, J P, Boehm, C D, Goff, S C, ...
To characterize systematically the mutations which produce beta-thalassemia in Asian Indians, we first determined the DNA polymorphism haplotype in the beta-globin gene cluster of 44 beta-thalassemia...
beta-Thalassemia due to a deletion of the nucleotide which is substituted in the beta S-globin gene.
Kazazian, H H, Orkin, S H, Boehm, C D, Sexton, J P, Antonarakis, S E
Sickle-cell anemia results from an A leads to T transversion in the second nucleotide of codon 6 of the beta-globin gene. We now report an uncommon beta-thalassemia gene that contains a deletion of...
ATA box transcription mutation in beta-thalassemia.
Orkin, S H, Sexton, J P, Cheng, T C, Goff, S C, Giardina, P J, Lee, J I, ...
DNA sequence analysis of a cloned beta-globin gene from a Chinese patient with beta-thalassemia revealed a single nucleotide substitution (A leads to G) within the ATA box homology and 28 base pairs...
beta-Thalassemia in American Blacks: novel mutations in the "TATA" box and an acceptor splice site.
Antonarakis, S E, Irkin, S H, Cheng, T C, Scott, A F, Sexton, J P, Trusko, S P, ...
beta-Thalassemia genes, although often mild in their effects, are common among American Blacks. We have begun a systematic molecular analysis of beta-thalassemia mutations in this group. DNA...
Cheng, T C, Orkin, S H, Antonarakis, S E, Potter, M J, Sexton, J P, Markham, A F, ...
To perform a systematic analysis of beta-thalassemia genes among Chinese, we have determined the DNA haplotype in the beta-globin gene region of 37 Chinese beta-thalassemia chromosomes. Only four...
Evidence for multiple origins of the beta E-globin gene in Southeast Asia.
Antonarakis, S E, Orkin, S H, Kazazian, H H, Goff, S C, Boehm, C D, Waber, P G, ...
To investigate whether recurrent mutation has contributed to the high frequency of the beta E-globin gene in Southeast Asia, we used the haplotypes at three polymorphic restriction sites within and...
Molecular characterization of seven beta-thalassemia mutations in Asian Indians.
Kazazian, H H, Orkin, S H, Antonarakis, S E, Sexton, J P, Boehm, C D, Goff, S C, ...
To characterize systematically the mutations which produce beta-thalassemia in Asian Indians, we first determined the DNA polymorphism haplotype in the beta-globin gene cluster of 44 beta-thalassemia...
beta-Thalassemia due to a deletion of the nucleotide which is substituted in the beta S-globin gene.
Kazazian, H H, Orkin, S H, Boehm, C D, Sexton, J P, Antonarakis, S E
Sickle-cell anemia results from an A leads to T transversion in the second nucleotide of codon 6 of the beta-globin gene. We now report an uncommon beta-thalassemia gene that contains a deletion of...