J. Pepke-Zaba

Impairment of pulmonary endothelium-dependent relaxation in patients with Eisenmenger's syndrome.

Dinh Xuan, A. T., Higenbottam, T. W., Clelland, C., Pepke-Zaba, J., Cremona, G., Wallwork, J.

A comparison has been made between the endothelium-dependent relaxation of pulmonary arteries (PA) obtained at heart-lung transplantation from 4 patients with Eisenmenger's syndrome and secondary...

Impairment of pulmonary-artery endothelium-dependent relaxation in chronic obstructive lung disease is not due to dysfunction of endothelial cell membrane receptors nor to L-arginine deficiency.

Dinh-Xuan, A. T., Pepke-Zaba, J., Butt, A. Y., Cremona, G., Higenbottam, T. W.

1. Endothelium-dependent relaxation mediated by endothelium-derived relaxing factor (EDRF) or nitric oxide (NO), is impaired in pulmonary arteries (PA) of hypoxic patients with chronic obstructive...

Role of computed tomographic scanning of the thorax prior to bronchoscopy in the investigation of suspected lung cancer

Laroche, C., Fairbairn, I., Moss, H., Pepke-Zaba, J., Sharples, L., Flower, C., ...

BACKGROUND—Fibreoptic bronchoscopy (FOB) is the usual initial investigation of choice in patients with suspected endobronchial carcinoma, but it is often non-diagnostic. Once a positive diagnosis...

Atrial septostomy in the treatment of severe pulmonary arterial hypertension

Reichenberger, F, Pepke-Zaba, J, McNeil, K, Parameshwar, J, Shapiro, L

Methods: Twenty AS performed in 17 patients with severe progressive PAH (13 primary pulmonary hypertension, two collagen vascular disease, one thromboembolic disease, one vaso-occlusive disease) were...