A role for heterocellular coupling and EETs in dilation of rat cremaster arteries (2006)
McSherry, I. N., Sandow, S. L., Campbell, W. B., Falck, J. R., Hill, M. A., Dora, K. A.
Pokreisz, Peter; U0032789, Vermeersch, Pieter; U0035259, Szelid, Z, Falck, J. R, Hammock, B. D, Fleming, I, ...
EDHF-like responses in rat cremaster muscle arterioles (2005)
McSherry, I. N., Sandow, S. L., Garland, C. J., Campbell, W. B., Falck, J. R., Hill, M. A., ...
Zeldin, D C, Plitman, J D, Kobayashi, J, Miller, R F, Snapper, J R, Falck, J R, ...
Cytochrome P450 metabolizes arachidonic acid to several unique and biologically active compounds in rabbit liver and kidney. Microsomal fractions prepared from rabbit lung homogenates metabolized...
Hirt, D L, Capdevila, J, Falck, J R, Breyer, M D, Jacobson, H R
AA is metabolized by a cytochrome P450, NADPH-dependent epoxygenase to four regioisomeric epoxyeicosatrienoic acids (EETs). The EETs are further hydrated enzymatically to their respective diols,...
Makita, K, Takahashi, K, Karara, A, Jacobson, H R, Falck, J R, Capdevila, J H
Excess dietary salt induces a cytochrome P450 arachidonic acid epoxygenase isoform in rat kidneys (Capdevila, J. H., S. Wei, J. Yang, A. Karara, H. R. Jacobson, J. R. Falck, F. P. Guengerich, and R....
Targeted killing of cultured cells by receptor-dependent photosensitization.
Mosley, S T, Goldstein, J L, Brown, M S, Falck, J R, Anderson, R G
This paper describes a method, designated "receptor-dependent photosensitization," by which the receptor-mediated endocytosis of low density lipoprotein (LDL) can be used to deliver a...
Visualization of acidic organelles in intact cells by electron microscopy.
Anderson, R G, Falck, J R, Goldstein, J L, Brown, M S
We report the synthesis of a probe that permits the visualization by electron microscopy of acidic organelles in intact cells. This probe, 3-(2,4-dinitroanilino)-3'-amino-N-methyldipropylamine...
Action of luteinizing hormone-releasing hormone: involvement of novel arachidonic acid metabolites.
Snyder, G D, Capdevila, J, Chacos, N, Manna, S, Falck, J R
Anterior pituitary cells were incubated in the presence of luteinizing hormone-releasing hormone and one of three inhibitors of arachidonic acid metabolism:indomethacin, an inhibitor of the...
Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding.
Gaidarov, I, Krupnick, J G, Falck, J R, Benovic, J L, Keen, J H
Internalization of agonist-activated G protein-coupled receptors is mediated by non-visual arrestins, which also bind to clathrin and are therefore thought to act as adaptors in the endocytosis...
Laussmann, T, Reddy, K M, Reddy, K K, Falck, J R, Vogel, G
Two diphospho-myo-inositol phosphates from Dictyostelium were recently investigated by two-dimensional 1H/31P NMR analysis and assigned to be either D-4-diphospho-myo-inositol pentakisphosphate...
Zeldin, D C, Plitman, J D, Kobayashi, J, Miller, R F, Snapper, J R, Falck, J R, ...
Cytochrome P450 metabolizes arachidonic acid to several unique and biologically active compounds in rabbit liver and kidney. Microsomal fractions prepared from rabbit lung homogenates metabolized...
Hirt, D L, Capdevila, J, Falck, J R, Breyer, M D, Jacobson, H R
AA is metabolized by a cytochrome P450, NADPH-dependent epoxygenase to four regioisomeric epoxyeicosatrienoic acids (EETs). The EETs are further hydrated enzymatically to their respective diols,...
Makita, K, Takahashi, K, Karara, A, Jacobson, H R, Falck, J R, Capdevila, J H
Excess dietary salt induces a cytochrome P450 arachidonic acid epoxygenase isoform in rat kidneys (Capdevila, J. H., S. Wei, J. Yang, A. Karara, H. R. Jacobson, J. R. Falck, F. P. Guengerich, and R....
Targeted killing of cultured cells by receptor-dependent photosensitization.
Mosley, S T, Goldstein, J L, Brown, M S, Falck, J R, Anderson, R G
This paper describes a method, designated "receptor-dependent photosensitization," by which the receptor-mediated endocytosis of low density lipoprotein (LDL) can be used to deliver a...
Visualization of acidic organelles in intact cells by electron microscopy.
Anderson, R G, Falck, J R, Goldstein, J L, Brown, M S
We report the synthesis of a probe that permits the visualization by electron microscopy of acidic organelles in intact cells. This probe, 3-(2,4-dinitroanilino)-3'-amino-N-methyldipropylamine...
Action of luteinizing hormone-releasing hormone: involvement of novel arachidonic acid metabolites.
Snyder, G D, Capdevila, J, Chacos, N, Manna, S, Falck, J R
Anterior pituitary cells were incubated in the presence of luteinizing hormone-releasing hormone and one of three inhibitors of arachidonic acid metabolism:indomethacin, an inhibitor of the...
Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding.
Gaidarov, I, Krupnick, J G, Falck, J R, Benovic, J L, Keen, J H
Internalization of agonist-activated G protein-coupled receptors is mediated by non-visual arrestins, which also bind to clathrin and are therefore thought to act as adaptors in the endocytosis...
Laussmann, T, Reddy, K M, Reddy, K K, Falck, J R, Vogel, G
Two diphospho-myo-inositol phosphates from Dictyostelium were recently investigated by two-dimensional 1H/31P NMR analysis and assigned to be either D-4-diphospho-myo-inositol pentakisphosphate...
Patel, Sachin, Wohlfeil, Eric R, Rademacher, David J, Carrier, Erica J, Perry, LaToya J, Kundu, Abhijit, ...
Propofol (2,6-diisopropylphenol) is widely used as a general anesthetic and for the maintenance of long-term sedation. We have tested the hypothesis that propofol alters endocannabinoid brain content...
Cheng, M K, Doumad, A B, Jiang, H, Falck, J R, McGiff, J C, Carroll, M A
Activation of rat adenosine 2A receptors (A2A R) dilates preglomerular microvessels (PGMV), an effect mediated by epoxyeicosatrienoic acids (EETs).Incubation of PGMV with a selective A2A R agonist,...
Stimulation of rat erythrocyte P2X7 receptor induces the release of epoxyeicosatrienoic acids
Jiang, H, Zhu, A G, Mamczur, M, Falck, J R, Lerea, K M, McGiff, J C
Lin, Hongying, Fridy, Peter C., Ribeiro, Anthony A., Choi, Jae H., Barma, Deb K., Vogel, Günter, ...
We have characterized the positional specificity of the mammalian and yeast VIP/diphosphoinositol pentakisphosphate kinase (PPIP5K) family of inositol phosphate kinases. We deployed a microscale...