J. R. Harris

Publication List Details

Period

1958 - 2007

Number

133

Co-Authors

Formation, TEM study and 3D reconstruction of the human erythrocyte peroxiredoxin-2 dodecahedral higher-order assembly (2007)

Meissner, U., Schröder, E., Scheffler, D., Martin, A.G., Harris, J.R.

The production of a higher-order assembly of peroxiredoxin-2 (Prx-2) from human erythrocytes has been achieved during specimen preparation on holey carbon support films, in the presence of ammonium...

Combined genome scans for body stature in 6,602 European twins: Evidence for common Caucasian loci (2007)

Perola, M., Sammalisto, S., Hiekkalinna, T., Martin, N. G., Visscher, P. M., Montgomery, G. W., ...

Twin cohorts provide a unique advantage for investigations of the role of genetics and environment in the etiology of variation in common complex traits by reducing the variance due to environment,...

Quaternary structure of the European spiny lobster (Palinurus elephas) 1 x 6-mer hemocyanin from cryoEM and amino acid sequence data (2003)

Meissner, U., Stohr, M., Kusche, K., Burmester, T., Stark, H., Harris, J. R., ...

Arthropod hemocyanins are large respiratory proteins that are composed of up to 48 subunits (8 x 6-mer) in the 75 kDa range. A 3D reconstruction of the 1 x 6-mer hemocyanin from the European spiny...

Heritability of adult body height: A comparative study of twin cohorts in eight countries (2003)

Silventoinen, K., Sammalisto, S., Perola, M., Boomsma, D. I., Cornes, B. K., Davis, C., ...

A major component of variation in body height is due to genetic differences, but environmental factors have a substantial contributory effect. In this study we aimed to analyse whether the genetic...

Two-dimensional crystals of the molecular chaperone GroEL reveal structural plasticity (1993)

Zahn, R., Harris, J. R., Pfeifer, G., Plückthun, A., Baumeister, W.

For two-dimensional (2-D) crystallization we have purified the molecular chaperone GroEL from Escherichia coli to homogeneity. The final and important step for crystallization in the purification...

Electron Microscopy of Human Erythrocyte Catalase: New Two-Dimensional Crystal Forms (1993)

Harris, J. R., Engelhardt, H., Volker, S., Holzenburg, A.

Using the mica-spreading "negative staining-carbon film" procedure, human erythrocyte catalase has been shown to create a number of different periodic or crystalline two-dimensional (2-D) arrays...

Structural features of the 26 S proteasome complex (1993)

Peters, J. M., Cejka, Z., Harris, J. R., Kleinschmidt, J. A., Baumeister, W.

Proteasomes play a key role in the degradation of abnormal proteins, of short-lived regulatory proteins and in antigen processing. Evidence is accumulating that the 20 S proteasome represents the...

Latency versus persistence or intermittent recurrences: evidence for a latent state of murine cytomegalovirus in the lungs.

Kurz, S, Steffens, H P, Mayer, A, Harris, J R, Reddehase, M J

The state of cytomegalovirus (CMV) after the resolution of acute infection is an unsolved problem in CMV research. While the term "latency" is in general use to indicate the maintenance of the viral...

Detection of urinary Vi antigen as a diagnostic test for typhoid fever.

Taylor, D N, Harris, J R, Barrett, T J, Hargrett, N T, Prentzel, I, Valdivieso, C, ...

Since Vi antigen is limited primarily to Salmonella typhi, it has been thought that detection of the antigen may be a useful method for diagnosing acute typhoid fever. The slide coagglutination...

Neisseria gonorrhoeae and ABO isohemagglutinins.

Miler, J J, Novotny, P, Walker, P D, Harris, J R, MacLennan, I P

Depending on the ABO blood group, gonorrhea may affect the titers of isohemagglutinins compared with those of uninfected controls. The isohemagglutinin titers in group O patients were significantly...

Disseminated pneumocystis carinii infection in AIDS.

Coker, R J, Clark, D, Claydon, E L, Gompels, M, Ainsworth, J G, Lucas, S B, ...

Eight patients with AIDS and Pneumocystis carinii infection were studied. Protean manifestations were a feature not untypical of disseminated pneumocystosis. Aerosolised pentamidine as prophylaxis...

Evaluation of a direct immunofluorescence test for diagnosing gonorrhoea.

Ison, C A, McLean, K, Gedney, J, Munday, P E, Coghill, D, Smith, R, ...

A new direct immunofluorescence reagent (Syva and Genetic Systems Inc) was evaluated for its ability to detect Neisseria gonorrhoeae in specimens from populations with a high prevalence of the...

Campylobacter pylori in the upper gastrointestinal tract of patients with HIV-1 infection.

Francis, N D, Logan, R P, Walker, M M, Polson, R J, Boylston, A W, Pinching, A J, ...

Fifty one patients with human immuno-deficiency virus (HIV-1) infection who had been consecutively endoscoped for upper gastrointestinal symptoms were biopsied (stomach or duodenum, or both) and...

Jejunal enteropathy associated with human immunodeficiency virus infection: quantitative histology.

Batman, P A, Miller, A R, Forster, S M, Harris, J R, Pinching, A J, Griffin, G E

Jejunal biopsy specimens from 20 human immunodeficiency virus (HIV) positive male homosexual patients were analysed and compared with those of a control group to determine whether the abnormalities...

Ribonucleic acid stimulation of mammalian liver nuclear-envelope nucleoside triphosphatase. A possible enzymic marker for the nuclear envelope.

Agutter, P S, Harris, J R, Stevenson, I

1. The specific activity of rat and pig liver nuclear-envelope nucleoside triphosphatase (EC 3.6.1.3) decreases when the system is depleted of RNA. The activity can be restored by adding high...

The use of pathologic features in selecting the extent of surgical resection necessary for breast cancer patients treated by primary radiation therapy.

Harris, J R, Connolly, J L, Schnitt, S J, Cady, B, Love, S, Osteen, R T, ...

The extent of the surgical resection necessary for breast cancer patients treated by primary radiation therapy is unknown. A simple gross excision of the tumor provides the best cosmetic result, but...

The optimal extent of resection for patients with stages I or II breast cancer treated with conservative surgery and radiotherapy.

Vicini, F A, Eberlein, T J, Connolly, J L, Recht, A, Abner, A, Schnitt, S J, ...

The optimal extent of breast resection before irradiation for treatment of early breast cancer has not been defined. Increasing the size of the resection may decrease the risk of local recurrence but...

Medical and social aspects of sexual assault of males: a survey of 100 victims.

Hillman, R J, O'Mara, N, Taylor-Robinson, D, Harris, J R

Sexual assault of males is an infrequently reported and a poorly understood phenomenon. Details of 100 victims who sought assistance from a nationwide agency set up specifically to provide help for...

Transmission of hepatitis B virus from adopted Asian children to their American families.

Friede, A, Harris, J R, Kobayashi, J M, Shaw, F E, Shoemaker-Nawas, P C, Kane, M A

In 1985, 6,991 Asian children were adopted by Americans. To estimate the risk that such children may transmit hepatitis B virus to their adoptive families, we conducted a cumulative-incidence...

Increased cesarean section rates and emerging patterns of health insurance in Shanghai, China.

Cai, W W, Marks, J S, Chen, C H, Zhuang, Y X, Morris, L, Harris, J R

OBJECTIVES: This study examined the trend in cesarean section deliveries and the factors associated with it in the Minhang District of Shanghai, China. METHODS: A representative sample of the members...

HIV testing: changing trends at a clinic for sexually transmitted diseases in London.

Beck, E J, Cunningham, D G, Moss, V W, Harris, J R, Pinching, A J, Jeffries, D J

Trends in human immunodeficiency virus (HIV) counselling and antibody testing at a London clinic for sexually transmitted diseases showed substantial changes over a 12 month period. From around 100 a...

Spectinomycin as initial treatment for gonorrhoea.

Easmon, C S, Forster, G E, Walker, G D, Ison, C A, Harris, J R, Munday, P E

The prevalence of penicillinase producing Neisseria gonorrhoeae at this hospital increased exponentially from less than 0.5% in 1978 to 6.5% of all isolates in 1982. In January 1983 first line...

Changing disease patterns in patients with AIDS in a referral centre in the United Kingdom: the changing face of AIDS.

Peters, B S, Beck, E J, Coleman, D G, Wadsworth, M J, McGuinness, O, Harris, J R, ...

OBJECTIVE--To study the changes in morbidity, mortality, and survival patterns in a population of patients with AIDS in the United Kingdom from 1982 to 1989. DESIGN--A retrospective analysis of...

Prostitution and risk of HIV: female prostitutes in London.

Ward, H, Day, S, Mezzone, J, Dunlop, L, Donegan, C, Farrar, S, ...

OBJECTIVE--To measure the prevalence of HIV and to describe established risk factors in female prostitutes. DESIGN--A cross sectional survey. SETTING--A genitourinary medicine clinic, streets, and...

Latency versus persistence or intermittent recurrences: evidence for a latent state of murine cytomegalovirus in the lungs.

Kurz, S, Steffens, H P, Mayer, A, Harris, J R, Reddehase, M J

The state of cytomegalovirus (CMV) after the resolution of acute infection is an unsolved problem in CMV research. While the term "latency" is in general use to indicate the maintenance of the viral...

Detection of urinary Vi antigen as a diagnostic test for typhoid fever.

Taylor, D N, Harris, J R, Barrett, T J, Hargrett, N T, Prentzel, I, Valdivieso, C, ...

Since Vi antigen is limited primarily to Salmonella typhi, it has been thought that detection of the antigen may be a useful method for diagnosing acute typhoid fever. The slide coagglutination...

Neisseria gonorrhoeae and ABO isohemagglutinins.

Miler, J J, Novotny, P, Walker, P D, Harris, J R, MacLennan, I P

Depending on the ABO blood group, gonorrhea may affect the titers of isohemagglutinins compared with those of uninfected controls. The isohemagglutinin titers in group O patients were significantly...

Disseminated pneumocystis carinii infection in AIDS.

Coker, R J, Clark, D, Claydon, E L, Gompels, M, Ainsworth, J G, Lucas, S B, ...

Eight patients with AIDS and Pneumocystis carinii infection were studied. Protean manifestations were a feature not untypical of disseminated pneumocystosis. Aerosolised pentamidine as prophylaxis...

Evaluation of a direct immunofluorescence test for diagnosing gonorrhoea.

Ison, C A, McLean, K, Gedney, J, Munday, P E, Coghill, D, Smith, R, ...

A new direct immunofluorescence reagent (Syva and Genetic Systems Inc) was evaluated for its ability to detect Neisseria gonorrhoeae in specimens from populations with a high prevalence of the...

Campylobacter pylori in the upper gastrointestinal tract of patients with HIV-1 infection.

Francis, N D, Logan, R P, Walker, M M, Polson, R J, Boylston, A W, Pinching, A J, ...

Fifty one patients with human immuno-deficiency virus (HIV-1) infection who had been consecutively endoscoped for upper gastrointestinal symptoms were biopsied (stomach or duodenum, or both) and...

Jejunal enteropathy associated with human immunodeficiency virus infection: quantitative histology.

Batman, P A, Miller, A R, Forster, S M, Harris, J R, Pinching, A J, Griffin, G E

Jejunal biopsy specimens from 20 human immunodeficiency virus (HIV) positive male homosexual patients were analysed and compared with those of a control group to determine whether the abnormalities...

Ribonucleic acid stimulation of mammalian liver nuclear-envelope nucleoside triphosphatase. A possible enzymic marker for the nuclear envelope.

Agutter, P S, Harris, J R, Stevenson, I

1. The specific activity of rat and pig liver nuclear-envelope nucleoside triphosphatase (EC 3.6.1.3) decreases when the system is depleted of RNA. The activity can be restored by adding high...

HIV testing: changing trends at a clinic for sexually transmitted diseases in London.

Beck, E J, Cunningham, D G, Moss, V W, Harris, J R, Pinching, A J, Jeffries, D J

Trends in human immunodeficiency virus (HIV) counselling and antibody testing at a London clinic for sexually transmitted diseases showed substantial changes over a 12 month period. From around 100 a...

The use of pathologic features in selecting the extent of surgical resection necessary for breast cancer patients treated by primary radiation therapy.

Harris, J R, Connolly, J L, Schnitt, S J, Cady, B, Love, S, Osteen, R T, ...

The extent of the surgical resection necessary for breast cancer patients treated by primary radiation therapy is unknown. A simple gross excision of the tumor provides the best cosmetic result, but...