Scientific Commons: J. R. Jass

Background & Aims: Sporadic colorectal cancers with a high degree of microsatellite instability are a clinically distinct subgroup with a high incidence of BRAF mutation and are widely considered to...

The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) - Results of an international collaborative study (2002)

Muller, W., Burgart, L. J., Krause-Paulus, R., Thibodeau, S. N., Almeida, M., Edmonston, T. B., ...

The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) - Results of an international collaborative study (2002)

Muller, W., Burgart, L. J., Krause-Paulus, R., Thibodeau, S. N., Almeida, M., Edmonston, T. B., ...

Histopathology of early neoplasia in Barrett's esophagus (2002)

Jass, J. R.

Lower gastrointestinal tract (2002)

Jass, J. R.

Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors (2002)

Lindor, N. M., Burgart, L. J., Leontovich, O., Goldberg, R. M., Cunningham, J. M., Sargent, D. J., ...

Purpose: To compare microsatellite instability (MSI) testing with immunohistochemical (IHC) detection of hMLH1 and hMSH2 in colorectal cancer. Patients and Methods: Colorectal cancers from 1, 144...

Serrated adenoma of the colorectum (2002)

Jass, J. R.

Molecular phenotyping in colorectal cancer: mutator versus methylator status (2002)

Whitehall, V. L., Wynter, C. V. A., Young, J. P., Leggett, B. A., Jass, J. R.

Hypermethylation of O6-methylguanine-DNA methyltransferase promoter as a good predictor for colorectal cancer patients receiving chemotherapy (2002)

Nagasaka, T., Sharp, G. B., Kambara, T., Sasamoto, H., Isozaki, H., Tanaka, N., ...

HPP1: A transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers (2001)

Young, J. P., Biden, K. G., Simms, L. A., Huggard, P.R., Karamatic, R., Eyre, H. J., ...

Adenomas are the precursors of most colorectal cancers. Hyperplastic polyps have been linked to the subset of colorectal cancers showing DNA microsatellite instability, but little is known of their...

Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability (2001)

Whitehall, V. L. J., Walsh, M. D., Young, J., Leggett, B. A., Jass, J. R.

The significance of low-level DNA microsatellite instability (MSI-L) is not well understood. K-ras mutation is associated with MSI-L colorectal cancer and with the silencing of the DNA repair gene...

The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) - Results of an international collaborative study (2001)

Muller, W., Burgart, L.J., Krause-Paulus, R., Thibodeau, S.N., Almeida, M.G., Bocker Edmonston, T., ...

Mechanism for low level DNA microsatellite instability in colorectal cancer (2001)

Jass, J. R., Whitehall, V. L., Walsh, M., Young, J. P., Leggett, B. A.

Distinction between familial (HNPCC) and sporadic MSI-H cancer (2001)

Jass, J. R.

Distinguishing pathological features of HNPCC versus sporadic MSI-H colorectal cancers (2001)

Jass, J. R., Walsh, M., Buttenshaw, R. L., Barker, M. A., Young, J. P., Leggett, B. A.

A New Instrument to Assess Synthesis of Inform (2001)

Jass, J. R., Alexander, H.G.I.

Association of sporadic MSI-H colorectal cancer and smoking in an Australian population (2001)

Chong, A. K., Young, J. P., Howlett, M., Leggett, B. A., Jass, J. R.

Differential expression analysis of microsatellite unstable colorectal cancers identifies novel gene targets (2001)

Whitehall, V. L., Jass, J. R., Young, J. P., Leggett, B. A.

Gene expression profiling of colorectal cancer cell lines (2001)

Simms, L. A., Williams, S., Taylor, J. M., Whitehall, V. L., Karamatic, R., Young, J. P., ...

Molecular clues to prognosis in sporadic colorectal cance (2001)

Whitehall, V. L., Walsh, M., Young, J. P., Leggett, B. A., Jass, J. R.

Mutation detection in MLH1 and MSH2 using DHPLC in high risk colorectal cancer families (2001)

Barker, M.A., Jass, J. R., Leggett, B. A., Young, J.P.

Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low level DNA microsatellite instability (2001)

Whitehall, V. L., Walsh, M., Young, J. P., Leggett, B. A., Jass, J. R.

Altered mucin expression in the gastrointestinal tract: a review (2001)

Jass, J. R., Walsh, M. D.

Early studies of changes in mucin expression in disorders of the gastrointestinal tract focused on alterations in the carbohydrate chain. This review briefly considers the various mechanisms by which...

Tumors of the small and large intestines (including the anal region) (2000)

Jass, J. R.

Tumours of the colon and rectum: Hereditary nonpolyposis colorectal cancer (2000)

Peltomaki, P., Vasen, H., Jass, J. R.

Tumours of the colon and rectum: Carcinoma of the colon and rectum (2000)

Hamilton, S. D., Vogelstein, B., Kudo, S., Riboli, E., Nakamura, S. H., Hainaut, P., ...

Tumours of the colon and rectum: Juvenile polyposis (2000)

Aaltonen, L. A., Jass, J. R., Howe, J. R.

Tumours of the small intestine: Peutz-Jeghers syndrome (2000)

Aaltonen, L. A., Jarvinen, H., Gruber, S. B., Billaud, M., Jass, J. R.

Tumours of the colon and rectum: Hyperplastic polyposis (2000)

Burt, R., Jass, J. R.

Histologically based methods for detection of mucin (2000)

Walsh, M., Jass, J. R.

HPP1: A novel transmembrane protein commonly methylated in colorectal polyps and cancers (2000)

Biden, K. G., Young, J. P., Simms, L. A., Karamatic, R., Barker, M.A., Anderson, G. J., ...

Juvenile polyposis lesions show clonal loss of SMAD4 in epithelial as well as stromal compartments, endorsing the "gatekeeper" not the "landscaper" hypothesis (2000)

Woodford-Richens, K., Williamson, J., Bevan, S., Young, J. P., Jass, J. R., Leggett, B. A., ...

Loss of heterozygosity on chromosome 22q in colorectal carcinomas and adenomas (2000)

Buttenshaw, R. L., Young, J. P., Jass, J. R., Leggett, B. A.

HPP1: A novel transmembrane protein commonly methylated in colorectal polyps and cancers (2000)

Biden, K. G., Young, J. P., Simms, L. A., Karamatic, R., Eyre, H. J., Sutherland, G. R., ...

The "highs" and "lows" of microsatellite instability in sporadic ACPS C colorectal cancer - improving prognostic stratification for this group of patients (2000)

Wright, C.M., Dent, O. F., Barker, M.A., Newland, R. C., Chapuis, P. H., Bokey, E. L., ...

Pathology and molecular features of colorectal tumours with microsatellite instability in familial and sporadic settings (2000)

Barker, M. A., Young, J. P., Buttenshaw, R. L., McKeone, D. M., Searle, J., Jass, J. R., ...

p14-ARF and p16-INK4A - one locus, two genes frequently affected in sporadic colorectal cancer (2000)

Whitehall, V. L., Walsh, M., Jass, J. R., Young, J. P., Leggett, B. A.

Isolation of HPP1 alternatively spliced transcripts using 3'-race (2000)

Simms, L. A., Young, J. P., Biden, K. G., Karamatic, R., Jass, J. R., Leggett, B. A.

A study of p14-ARF in sporadic colorectal cancer (2000)

Whitehall, V. L., Walsh, M., Jass, J. R., Young, J. P., Leggett, B. A.

Familial colorectal cancer: pathology and molecular characteristics (2000)

Jass, J. R.

Pathology of hereditary nonpolyposis colorectal cancer (2000)

Jass, J. R.

hMLH1 and hMSH2 immunostaining in colorectal cancer (2000)

Jass, J. R.

The apoptotic regulatory gene, BCL10, is mutated in sporadic mismatch repair deficient colorectal cancers (2000)

Simms, L. A., Young, J., Wicking, C., Meltzer, S. J., Jass, J. R., Leggett, B. A.

Anal cancer subtype reproducibility study (2000)

Fenger, C., Frisch, M., Jass, J. R., Williams, G., Hilden, J.

Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis (2000)

Biemer-Huttmann, A. E., Walsh, M. D., McGuckin, M. A., Simms, L. A., Young, J., Leggett, B. A., ...

Particular mucinous phenotypes have been associated with serrated epithelial polyps of the colon. These polyps also show a high frequency of DNA instability. The aim of this study was to examine the...

DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer (2000)

Iino, H., Simms, L., Young, J. P., Arnold, J., Winship, I. M., Webb, S. I., ...

Background and aim-Hereditary nonpolyposis colorectal cancer (HNPCC), as its name implies, is associated with few adenomas, and the early evolution of colorectal neoplasia is poorly understood. In...

Discrepancies between East and West (2000)

Jass, J. R.

Adenocarcinoma of colon differentiating as dome epithelium of gut-associated lymphoid tissue (2000)

Jass, J. R., Constable, L., Sutherland, R., Winterford, CM, Walsh, M., Young, J. P., ...

Aims: An early adenocarcinoma of the ascending colon was confined to a mass of gut-associated lymphoid tissue (GALT). The first description of an adenocarcinoma of colon differentiating as dome...

Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum (2000)

Jass, J. R., Iino, H., Ruszkiewicz, A., Painter, D., Solomon, M. J., Koorey, D. J., ...

Aim-Colorectal cancer has been described in association with hyperplastic polyposis but the mechanism underlying this observation is unknown. The aim of this study was to characterise foci of...

Mutations associated with MSI+ colorectal carcinomas exhibit widespread intratumoral heterogeneity (2000)

Barnetson, R., Jass, J. R., Tse, R., Eckstein, R., Robinson, B., Schnitzler, M.

Adenocarcinoma of colon differentiating as dome epithelium of gut-associated lymphoid tissue (2000)

Clouston, A. D., Clouston, D. R., Jass, J. R.

Mutations associated with microsatellite unstable colorectal carcinomas exhibit widespread intratumoral heterogeneity (2000)

Barnetson, R., Jass, J. R., Tse, R., Eckstein, R., Robinson, B., Schnitzler, M.

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways (1999)

Jass, J. R., Biden, K. G., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., ...

Background-10% of sporadic colorectal cancers are characterised by a low level of microsatellite instability (MSI-L). These are not thought to differ substantially from microsatellite-stable (MSS)...

Interface of histopathology and familial cancer (1999)

Jass, J. R.

Tumour pathology (1999)

Jass, J. R.

A case of myoepithelial carcinoma in a FAP family (1999)

Barker, M. A., Knight, M., Young, J. P., Buttenshaw, R. L., Jass, J. R., Leggett, B. A.

Microsatellite instability testing of tumours occurring in high-risk colorectal cancer families (1999)

Barker, M. A., Young, J. P., Webb, S. I., Buttenshaw, R. L., McKeone, D. M., Neal, J. I., ...

Microsatellite instability occurs early in adenoma development in hereditary non-polyposis colorectal cancer and becomes more extensive with the development of high grade dysplasia (1999)

Iino, H., Young, J. P., Simms, L. A., Jass, J. R., Leggett, B. A.

Novel pathways of colorectal carcinogenesis (1999)

Jass, J. R.