The molecular cloning and fine-structure analysis of the homoprotocatechuate (hpc) catabolic pathway genes of Escherichia coli C are described. The genes were located in two operons, hpcBCDEF and...
Ability of p53 and the adenovirus E1b 58-kilodalton protein to form a complex is determined by p53.
Braithwaite, A W, Jenkins, J R
We have investigated p53-E1b 58-kilodalton (kDa) protein complex formation during permissive and semipermissive infections with adenovirus type 5 (Ad5) dl309. While metabolic labeling studies easily...
Jenkins, J R, Chumakov, P, Addison, C, Stürzbecher, H W, Wade-Evans, A
We mapped regions of the mouse p53 primary amino acid sequence implicated in stable complex formation with simian virus 40 T antigen. A number of mutant p53 proteins failed to complex stably with T...
Human cells express two differentially spliced forms of topoisomerase II beta mRNA.
Davies, S L, Jenkins, J R, Hickson, I D
Screening of a human B-cell cDNA library with a topoisomerase II beta gene-specific probe revealed the presence of two distinct forms of topoisomerase II beta cDNA. One form (designated topoisomerase...
Jenkins, J R, Rudge, K, Redmond, S, Wade-Evans, A
We have cloned and sequenced overlapping cDNA fragments which together encode the entire mouse protein p53. Using these cDNA's we have reconstructed the full length coding region for the protein, and...
Molecular cloning of three major sequence species from Rainbow trout protamine mRNA.
Jenkins, J R, Bishop, J O, Butterworth, P H
Double stranded cDNA molecules complementary to purified Rainbow trout protamine mRNA have been cloned in the bacterial plasmid pBR322. In order to circumvent the problems associated with a...
Jenkins, J R, Ayton, P, Jones, T, Davies, S L, Simmons, D L, Harris, A L, ...
Topoisomerases catalyse the interconversion of topological isomers of DNA and have key roles in nucleic acid metabolism. Human cells express two distinct type II topoisomerase isozymes, designated...
Remm, M, Brain, R, Jenkins, J R
Human papillomaviruses (HPV-s) have been shown to possess transforming and immortalizing activity for many different, mainly keratinocyte cell lines and they have been detected in 90% of anogenital...
Stürzbecher, H W, Addison, C, Jenkins, J R
Several mutant, but not wild-type, p53 proteins form complexes with hsp72/73 heat shock-related proteins in simian virus 40-transformed monkey COS cells. We carried out a detailed biochemical and...
Slingerland, J M, Jenkins, J R, Benchimol, S
Mutant p53 alleles that have a recessive phenotype in human tumors can, in cooperation with an activated H-ras gene, transform rat embryo fibroblasts (REFs). Mutant p53 proteins differ from wild...
Precise epitope mapping of the murine transformation-associated protein, p53.
Murine p53 cDNA sequences were cloned into an in vitro expression vector, Protem Hind. Four deletion libraries were generated using Bal31 double-stranded exonuclease; two being made from constructs...
The molecular cloning and fine-structure analysis of the homoprotocatechuate (hpc) catabolic pathway genes of Escherichia coli C are described. The genes were located in two operons, hpcBCDEF and...
Ability of p53 and the adenovirus E1b 58-kilodalton protein to form a complex is determined by p53.
Braithwaite, A W, Jenkins, J R
We have investigated p53-E1b 58-kilodalton (kDa) protein complex formation during permissive and semipermissive infections with adenovirus type 5 (Ad5) dl309. While metabolic labeling studies easily...
Jenkins, J R, Chumakov, P, Addison, C, Stürzbecher, H W, Wade-Evans, A
We mapped regions of the mouse p53 primary amino acid sequence implicated in stable complex formation with simian virus 40 T antigen. A number of mutant p53 proteins failed to complex stably with T...
Human cells express two differentially spliced forms of topoisomerase II beta mRNA.
Davies, S L, Jenkins, J R, Hickson, I D
Screening of a human B-cell cDNA library with a topoisomerase II beta gene-specific probe revealed the presence of two distinct forms of topoisomerase II beta cDNA. One form (designated topoisomerase...
Jenkins, J R, Rudge, K, Redmond, S, Wade-Evans, A
We have cloned and sequenced overlapping cDNA fragments which together encode the entire mouse protein p53. Using these cDNA's we have reconstructed the full length coding region for the protein, and...
Molecular cloning of three major sequence species from Rainbow trout protamine mRNA.
Jenkins, J R, Bishop, J O, Butterworth, P H
Double stranded cDNA molecules complementary to purified Rainbow trout protamine mRNA have been cloned in the bacterial plasmid pBR322. In order to circumvent the problems associated with a...
Jenkins, J R, Ayton, P, Jones, T, Davies, S L, Simmons, D L, Harris, A L, ...
Topoisomerases catalyse the interconversion of topological isomers of DNA and have key roles in nucleic acid metabolism. Human cells express two distinct type II topoisomerase isozymes, designated...
Remm, M, Brain, R, Jenkins, J R
Human papillomaviruses (HPV-s) have been shown to possess transforming and immortalizing activity for many different, mainly keratinocyte cell lines and they have been detected in 90% of anogenital...
Stürzbecher, H W, Addison, C, Jenkins, J R
Several mutant, but not wild-type, p53 proteins form complexes with hsp72/73 heat shock-related proteins in simian virus 40-transformed monkey COS cells. We carried out a detailed biochemical and...
Slingerland, J M, Jenkins, J R, Benchimol, S
Mutant p53 alleles that have a recessive phenotype in human tumors can, in cooperation with an activated H-ras gene, transform rat embryo fibroblasts (REFs). Mutant p53 proteins differ from wild...
Precise epitope mapping of the murine transformation-associated protein, p53.
Murine p53 cDNA sequences were cloned into an in vitro expression vector, Protem Hind. Four deletion libraries were generated using Bal31 double-stranded exonuclease; two being made from constructs...