Lorena, D, Darby, I, Gadeau, A, Leen, L, Rittling, S, Porto, L, ...
BACKGROUND/AIMS - Osteopontin has been implicated in numerous physiopathological events. Osteopontin expression in normal and fibrotic liver and liver fibrogenesis in osteopontin-deficient mice were...
Lorena, D, Darby, I, Reinhardt, D, Sapin, V, Rosenbaum, J, Desmouliere, A
Fibrillin-1, together with elastin, is the main component of elastic fibers found throughout the extracellular space and responsible for the biomechanical properties of most tissues and organs. In...
Bisson, C, Blacher, Silvia, Polette, M, Blanc, JF, Kebers, F, Desreux, Joëlle, ...
The membrane type-1 matrix metalloproteinase (MT1-MMP), a protease originally identified in breast carcinoma, is characterized by its capacity to activate other MMPs (MMP-2 and MMP-13) and to degrade...
Fully-Stressed Design of Airframe Redundant Structures (1998)
Dwyer, W., Rosenbaum, J., Shulman, M., Pardo, H.
This paper presents a description of two automated, fully stressed design procedures for airframe redundant structures along with wing box beam examples. One of the methods is a variation of the...
Heparan sulfate proteoglycan expression in chronic cholestatic human liver diseases (1996)
The mechanism of bile ductular reaction and accompanying fibrogenesis depends on interactions of ductular cells with the matrix and growth factors. Heparan sulfate proteoglycans (HSPGs) are essential...
Computer-Based Instruction in Statistical Inference. (1967)
Rosenbaum,J., Feingold,S. L., Frye,C. H., Bennik,F. D.
This report describes a two-year investigation into the development and use of computer-assisted instruction (CAI) for the improvement of undergraduate training in statistics. The target student in...
Mallat, A, Fouassier, L, Préaux, A M, Gal, C S, Raufaste, D, Rosenbaum, J, ...
Ito cells play a pivotal role in the development of liver fibrosis associated with chronic liver diseases. During this process, Ito cells acquire myofibroblastic features, proliferate, and synthesize...
Middlestadt, S E, Bhattacharyya, K, Rosenbaum, J, Fishbein, M, Shepherd, M
Through one of its many HIV prevention programs, the Prevention Marketing Initiative, the Centers for Disease Control and Prevention promotes a multifaceted strategy for preventing the sexual...
Mallat, A, Fouassier, L, Préaux, A M, Gal, C S, Raufaste, D, Rosenbaum, J, ...
Ito cells play a pivotal role in the development of liver fibrosis associated with chronic liver diseases. During this process, Ito cells acquire myofibroblastic features, proliferate, and synthesize...
Middlestadt, S E, Bhattacharyya, K, Rosenbaum, J, Fishbein, M, Shepherd, M
Through one of its many HIV prevention programs, the Prevention Marketing Initiative, the Centers for Disease Control and Prevention promotes a multifaceted strategy for preventing the sexual...
Hepatotoxicity associated with use of D-penicillamine in rheumatoid arthritis.
Rosenbaum, J, Katz, W A, Schumacher, H R
Two patients with rheumatoid arthritis developed evidence of hepatotoxicity while receiving D-penicillamine. Both recovered after withdrawal of the drug. These cases and a review of the literature...
Moraxella infectious arthritis: first report in an adult.
Rosenbaum, J, Lieberman, D H, Katz, W A
The first occurrence of septic arthritis due to moraxella in an adult is reported. The clinical presentation mimicked disseminated gonococcaemia with associated gonococcal arthritis except for an...
Plasma von Willebrand factor in connective tissue disease.
Gordon, J L, Pottinger, B E, Woo, P, Rosenbaum, J, Black, C M
Characterisation of uveitis in patients with psoriatic arthritis
Paiva, E., Macaluso, D., Edwards, A., Rosenbaum, J.
OBJECTIVE—The purpose of this study is to describe the clinical characteristics of uveitis related to psoriatic arthritis (PsA), and also to compare the uveitis in PsA to the uveitis in...
Osteonectin (SPARC) expression in human liver and in cultured human liver myofibroblasts.
Blazejewski, S., Le Bail, B., Boussarie, L., Blanc, J. F., Malaval, L., Okubo, K., ...
Osteonectin/SPARC is a glycoprotein involved in the regulation of cell shape, adhesion, migration, and proliferation. It also has complex effects on extracellular matrix synthesis and turnover. We...
Rosenbaum, J., Simpson, J., Neuwelt, C
BACKGROUND—Optic neuropathy is a rare manifestation of systemic lupus erythematosus (SLE). In a previous series most patients with optic neuropathy in association with SLE had a final visual acuity...
A role for methotrexate in the management of non-infectious orbital inflammatory disease
AIM—To evaluate the clinical usefulness of methotrexate for patients with non-infectious orbital inflammatory disease who fail to respond to systemic corticosteroids and/or orbital...
Rosenbaum, J, Pottinger, B E, Woo, P, Black, C M, Loizou, S, Byron, M A, ...
We have detected circulating IgG antibodies that bind with high affinity to human umbilical vein endothelial cells in 74% of patients with systemic lupus erythematosus (SLE), 30% of those with...
Reynaert, H, Rombouts, K, Vandermonde, A, Urbain, D, Kumar, U, Bioulac-Sage, P, ...
Background: Somatostatin analogues have been used with conflicting results to treat advanced hepatocellular carcinoma (HCC). The aim of this study was to investigate expression of somatostatin...
A role for thrombin in liver fibrosis
Duplantier, J Gillibert, Dubuisson, L, Senant, N, Freyburger, G, Laurendeau, I, Herbert, J-M, ...
Background/Aim: Several lines of evidence incriminate the serine proteinase thrombin in liver fibrogenesis either through its procoagulant function or its signaling via cell-surface receptors. The...
Barre, J, Mallat, A, Rosenbaum, J, Deforges, L, Houin, G, Dhumeaux, D, ...
Pharmacokinetic parameters were studied after i.v. infusion of erythromycin (500 mg) in five patients with alcoholic cirrhosis and six normal subjects. Serum AAG levels were 4.7 +/- 2.4 mumol l-1 in...
Decreased alpha 1-acid glycoprotein in liver cirrhosis: consequences for drug protein binding.
Barre, J, Houin, G, Rosenbaum, J, Zini, R, Dhumeaux, D, Tillement, J P
Fibroproliferation and mast cells in the acute respiratory distress syndrome
Liebler, J., Qu, Z., Buckner, B., Powers, M., Rosenbaum, J.
BACKGROUND—Mast cells (MCs), which are a major source of cytokines and growth factors, have been implicated in various fibrotic disorders. To clarify the contribution of MCs to fibrogenesis, lung...