J. Ross Fitzgerald

Characterization of Staphylococcus aureus Enterotoxin L (2003)

Orwin, Paul M., Fitzgerald, J. Ross, Leung, Donald Y. M., Gutierrez, Juan A., Bohach, Gregory A., Schlievert, Patrick M.

Staphylococcus aureus causes a wide variety of diseases. Major virulence factors of this organism include enterotoxins (SEs) that cause both food poisoning and toxic shock syndrome. Recently, a novel...

Evolutionary genomics of Staphylococcus aureus: Insights into the origin of methicillin-resistant strains and the toxic shock syndrome epidemic

Fitzgerald, J. Ross, Sturdevant, Daniel E., Mackie, Stacy M., Gill, Steven R., Musser, James M.

An emerging theme in medical microbiology is that extensive variation exists in gene content among strains of many pathogenic bacterial species. However, this topic has not been investigated on a...

Characterization of a Putative Pathogenicity Island from Bovine Staphylococcus aureus Encoding Multiple Superantigens

Fitzgerald, J. Ross, Monday, Steven R., Foster, Timothy J., Bohach, Gregory A., Hartigan, Patrick J., Meaney, William J., ...

Previous studies have demonstrated that a proportion of Staphylococcus aureus isolates from bovine mastitis coproduce toxic shock syndrome toxin (TSST) and staphylococcal enterotoxin C (SEC). In this...

Genome Sequence Survey Identifies Unique Sequences and Key Virulence Genes with Unusual Rates of Amino Acid Substitution in Bovine Staphylococcus aureus

Herron, Lisa L., Chakravarty, Rajit, Dwan, Christopher, Fitzgerald, J. Ross, Musser, James M., Retzel, Ernest, ...

Staphylococcus aureus is a major cause of mastitis in bovine and other ruminant species. We here present the results of a comparative genomic analysis between a bovine mastitis-associated clone,...

Staphylococcus aureus Aconitase Inactivation Unexpectedly Inhibits Post-Exponential-Phase Growth and Enhances Stationary-Phase Survival

Somerville, Greg A., Chaussee, Michael S., Morgan, Carrie I., Fitzgerald, J. Ross, Dorward, David W., Reitzer, Lawrence J., ...

Staphylococcus aureus preferentially catabolizes glucose, generating pyruvate, which is subsequently oxidized to acetate under aerobic growth conditions. Catabolite repression of the tricarboxylic...

In Vitro Serial Passage of Staphylococcus aureus: Changes in Physiology, Virulence Factor Production, and agr Nucleotide Sequence

Somerville, Greg A., Beres, Stephen B., Fitzgerald, J. Ross, DeLeo, Frank R., Cole, Robert L., Hoff, Jessica S., ...

Recently, we observed that Staphylococcus aureus strains newly isolated from patients had twofold-higher aconitase activity than a strain passaged extensively in vitro, leading us to hypothesize that...

Genome Diversification in Staphylococcus aureus: Molecular Evolution of a Highly Variable Chromosomal Region Encoding the Staphylococcal Exotoxin-Like Family of Proteins

Fitzgerald, J. Ross, Reid, Sean D., Ruotsalainen, Eeva, Tripp, Timothy J., Liu, MengYao, Cole, Robert, ...

Recent genomic studies have revealed extensive variation in natural populations of many pathogenic bacteria. However, the evolutionary processes which contribute to much of this variation remain...

Characterization of Staphylococcus aureus Enterotoxin L

Orwin, Paul M., Fitzgerald, J. Ross, Leung, Donald Y. M., Gutierrez, Juan A., Bohach, Gregory A., Schlievert, Patrick M.

Staphylococcus aureus causes a wide variety of diseases. Major virulence factors of this organism include enterotoxins (SEs) that cause both food poisoning and toxic shock syndrome. Recently, a novel...

Evolutionary genomics of Staphylococcus aureus: Insights into the origin of methicillin-resistant strains and the toxic shock syndrome epidemic

Fitzgerald, J. Ross, Sturdevant, Daniel E., Mackie, Stacy M., Gill, Steven R., Musser, James M.

An emerging theme in medical microbiology is that extensive variation exists in gene content among strains of many pathogenic bacterial species. However, this topic has not been investigated on a...

Characterization of a Putative Pathogenicity Island from Bovine Staphylococcus aureus Encoding Multiple Superantigens

Fitzgerald, J. Ross, Monday, Steven R., Foster, Timothy J., Bohach, Gregory A., Hartigan, Patrick J., Meaney, William J., ...

Previous studies have demonstrated that a proportion of Staphylococcus aureus isolates from bovine mastitis coproduce toxic shock syndrome toxin (TSST) and staphylococcal enterotoxin C (SEC). In this...

Genome Sequence Survey Identifies Unique Sequences and Key Virulence Genes with Unusual Rates of Amino Acid Substitution in Bovine Staphylococcus aureus

Herron, Lisa L., Chakravarty, Rajit, Dwan, Christopher, Fitzgerald, J. Ross, Musser, James M., Retzel, Ernest, ...

Staphylococcus aureus is a major cause of mastitis in bovine and other ruminant species. We here present the results of a comparative genomic analysis between a bovine mastitis-associated clone,...

Staphylococcus aureus Aconitase Inactivation Unexpectedly Inhibits Post-Exponential-Phase Growth and Enhances Stationary-Phase Survival

Somerville, Greg A., Chaussee, Michael S., Morgan, Carrie I., Fitzgerald, J. Ross, Dorward, David W., Reitzer, Lawrence J., ...

Staphylococcus aureus preferentially catabolizes glucose, generating pyruvate, which is subsequently oxidized to acetate under aerobic growth conditions. Catabolite repression of the tricarboxylic...

In Vitro Serial Passage of Staphylococcus aureus: Changes in Physiology, Virulence Factor Production, and agr Nucleotide Sequence

Somerville, Greg A., Beres, Stephen B., Fitzgerald, J. Ross, DeLeo, Frank R., Cole, Robert L., Hoff, Jessica S., ...

Recently, we observed that Staphylococcus aureus strains newly isolated from patients had twofold-higher aconitase activity than a strain passaged extensively in vitro, leading us to hypothesize that...

Genome Diversification in Staphylococcus aureus: Molecular Evolution of a Highly Variable Chromosomal Region Encoding the Staphylococcal Exotoxin-Like Family of Proteins

Fitzgerald, J. Ross, Reid, Sean D., Ruotsalainen, Eeva, Tripp, Timothy J., Liu, MengYao, Cole, Robert, ...

Recent genomic studies have revealed extensive variation in natural populations of many pathogenic bacteria. However, the evolutionary processes which contribute to much of this variation remain...

Characterization of Staphylococcus aureus Enterotoxin L

Orwin, Paul M., Fitzgerald, J. Ross, Leung, Donald Y. M., Gutierrez, Juan A., Bohach, Gregory A., Schlievert, Patrick M.

Staphylococcus aureus causes a wide variety of diseases. Major virulence factors of this organism include enterotoxins (SEs) that cause both food poisoning and toxic shock syndrome. Recently, a novel...

Population Genetic Structure of the Staphylococcus intermedius Group: Insights into agr Diversification and the Emergence of Methicillin-Resistant Strains▿ †

Bannoehr, Jeanette, Ben Zakour, Nouri L., Waller, Andrew S., Guardabassi, Luca, Thoday, Keith L., ...

The population genetic structure of the animal pathogen Staphylococcus intermedius is poorly understood. We carried out a multilocus sequence phylogenetic analysis of isolates from broad host and...