Rice, R J, Bhullar, V, Mitchell, S H, Bullard, J, Knapp, J S
The in vitro susceptibilities of 45 recent clinical isolates of Chlamydia trachomatis obtained from women with asymptomatic genital tract infection, mucopurulent cervicitis, or pelvic inflammatory...
In vitro activity of a new fluoroquinolone, CP-99,219, against strains of Neisseria gonorrhoeae.
Knapp, J S, Neal, S W, Parekh, M C, Rice, R J
The susceptibilities of 216 strains of Neisseria gonorrhoeae to a new fluoroquinolone, CP-99,219 were determined. For strains for which the MICs of ciprofloxacin were < or = 0.06 microgram/ml, the...
Knapp, J S, Hale, J A, Neal, S W, Wintersheid, K, Rice, R J, Whittington, W L
The susceptibilities of 45 strains of Neisseria gonorrhoeae, including 25 strains susceptible to ciprofloxacin (MICs, < or = 0.06 microgram/ml) and 20 strains exhibiting decreased susceptibilities to...
Van Der Willigen, A H, Wagenvoort, J H, Schalla, W O, Knapp, J S, Boot, J M, Heeres-Weststrate, P L, ...
Uncomplicated urogenital and concomitant oropharyngeal gonorrhea in 424 male and female patients was treated in a randomized comparative study with 0.5 g of cefodizime (89 men and 54 women), 1 g of...
High-level tetracycline resistance in strains of Neisseria gonorrhoeae, Neisseria meningitidis, Kingella denitrificans, and Eikenella corrodens has recently been described. The resistance in each...
Knapp, J S, Johnson, S R, Zenilman, J M, Roberts, M C, Morse, S A
Similar to Neisseria gonorrhoeae, tetracycline-resistant isolates of N. meningitidis, Kingella denitrificans, and Eikenella corrodens contained 25.2-megadalton plasmids carrying the TetM determinant....
Van Der Willigen, A H, Van Der Hoek, J C, Wagenvoort, J H, Van Vliet, H J, Van Klingeren, B, Schalla, W O, ...
In a double-blind randomized study, 155 male patients with uncomplicated urethral gonorrhea were given 200 mg (one capsule with 200 mg and one capsule with placebo; n = 77) or 400 mg (two capsules...
Two highly tetracycline-resistant, beta-lactamase-producing Neisseria gonorrhoeae strains were used as donors for conjugation with Neisseria meningitidis and commensal Neisseria species. We found...
Knapp, J S, Back, A F, Babst, A F, Taylor, D, Rice, R J
We determined the in vitro susceptibilities of 54 isolates of Haemophilus ducreyi from Thailand (29 isolates) and San Francisco (25 isolates) to penicillin G, tetracycline, amoxicillin-clavulanic...
Antimicrobial susceptibilities of Neisseria gonorrhoeae strains isolated in Surabaya, Indonesia.
Joesoef, M R, Knapp, J S, Idajadi, A, Linnan, M, Barakbah, Y, Kamboji, A, ...
Until recently, the only common strains of antimicrobial agent-resistant Neisseria gonorrhoeae detected in Indonesia were penicillinase-producing N. gonorrhoeae (PPNG) strains. Despite the spread of...
Motley, M, Sarafian, S K, Knapp, J S, Zaidi, A A, Schmid, G
We determined the susceptibilities of 94 strains of Haemophilus ducreyi isolated in various municipalities in the United States between 1982 and 1989 to the following antimicrobial agents:...
Immunoglobulin A1 (IgA1) proteases are extracellular bacterial proteolytic enzymes which correlate with virulence in several species of human pathogens. We report that Neisseria gonorrhoeae produced...
Tenover, F C, Knapp, J S, Patton, C, Plorde, J J
A chemically defined medium developed for Neisseria gonorrhoeae was modified to support the growth of Campylobacter jejuni and Campylobacter coli. A total of 76 isolates of C. jejuni and 14 isolates...
Anaerobic growth of Neisseria gonorrhoeae coupled to nitrite reduction.
A total of 204 Neisseria gonorrhoeae strains, including 39 penicillinase-producing strains, representing 64 distinct auxotype and serovar classes were tested for their ability to grow anaerobically...
Beebe, J L, Rau, M P, Flageolle, S, Calhoon, B, Knapp, J S
To determine the accuracy of the Syva (Palo Alto, Calif.) direct fluorescent-antibody (DFA) test in comparison with the Gen-Probe (San Diego, Calif.) Accuprobe culture confirmation test, we tested...
Panel of reference strains for evaluating serologic reagents used to identify gonococci.
Evins, G M, Pigott, N E, Knapp, J S, DeWitt, W E
A panel of strains for evaluating Neisseria gonorrhoeae serologic reagents was developed. The strains selected for the panel were antigenically diverse and representative of strains isolated...
Certain strains of Neisseria gonorrhoeae have been used by numerous investigators to develop serologic classification systems. Some of these strains have been used by investigators to study...
Prevalence and persistence of Neisseria cinerea and other Neisseria spp. in adults.
Neisseria cinerea is a commensal Neisseria sp. which was first described in 1906 but was subsequently misclassified as a subtype of Branhamella catarrhalis. N. cinerea resembles Neisseria gonorrhoeae...
Jones, R N, Gavan, T L, Thornsberry, C, Fuchs, P C, Gerlach, E H, Knapp, J S, ...
A six-laboratory study developed a standardized method for determining the susceptibilities of Neisseria gonorrhoeae strains to penicillin, tetracycline, spectinomycin, and ceftriaxone. Three quality...
Del Rio, C, Stephens, D S, Knapp, J S, Rice, R J, Schalla, W O
We studied a previously healthy 20-year-old woman who presented with gonococcal meningitis. The gonococcal isolate, HT-1, was prototrophic by auxotyping, was protein I serovar IB-1, and agglutinated...
Production of 14C-labeled gas in BACTEC Neisseria Differentiation kits by Neisseria cinerea.
Boyce, J M, Mitchell, E B, Knapp, J S, Buttke, T M
Six strains of Neisseria cinerea were tested in BACTEC Neisseria Differentiation kits (Johnston Laboratories, Inc., Towson, Md.), and all yielded positive glucose growth indices and negative maltose...
Binding of S protein by Neisseria gonorrhoeae and potential role in invasion.
Arko, R J, Chen, C Y, Schalla, W O, Sarafian, S K, Taylor, C L, Knapp, J S, ...
An agglutination assay was used to examine the binding of purified human S protein (vitronectin, serum spreading factor) to 201 clinical isolates of Neisseria gonorrhoeae. Strains belonging to the...
Molecular characterization of Haemophilus ducreyi by ribosomal DNA fingerprinting.
Sarafian, S K, Woods, T C, Knapp, J S, Swaminathan, B, Morse, S A
Intraspecies genotypic heterogeneity among Haemophilus ducreyi isolates was examined by using genomic fingerprints with rRNA from Escherichia coli as a probe. DNA from 44 isolates of H. ducreyi was...
Novel plasmid combinations in Haemophilus ducreyi isolates from Thailand.
Sarafian, S K, Johnson, S R, Thomas, M L, Knapp, J S
Thirty isolates of Haemophilus ducreyi collected in Thailand in 1984 were characterized by plasmid content. Three novel plasmids with estimated molecular masses of 1.8, 2.6, and 2.8 MDa were observed...
A modified oxidation-fermentation medium was developed as a practical medium for highly sensitive and specific detection of acid production from carbohydrates by Neisseria spp. and Branhamella...
Gonococcal sensitivity to fecal lipids can be mediated by an Mtr-independent mechanism.
McFarland, L, Mietzner, T A, Knapp, J S, Sandstrom, E, Holmes, K K, Morse, S A
Various factors affect the sensitivity of Neisseria gonorrhoeae to physiological levels of hydrophobic molecules. A total of 98 N. gonorrhoeae strains from rectal, cervical, and urethral cultures of...
Knapp, J S, Totten, P A, Mulks, M H, Minshew, B H
An asaccharolytic, gram-negative, oxidase-positive diplococcus was isolated on Martin-Lewis medium from the cervix of a patient attending an arthritis clinic at Seattle Public Health Hospital,...
Chen, K C, Knapp, J S, Holmes, K K
A rapid method was developed for specific detection of microbial beta-lactamases which uses ampicillin and cephalexin as substrates. The end products (open beta-lactam ring forms) generated after...
Nosocomial pneumonia caused by a glucose-metabolizing strain of Neisseria cinerea.
Boyce, J M, Taylor, M R, Mitchell, E B, Knapp, J S
We describe what appears to be the first reported case of nosocomial pneumonia caused by Neisseria cinerea. The isolate metabolized glucose when tested in BACTEC Neisseria Differentiation Kits...
Proctitis associated with Neisseria cinerea misidentified as Neisseria gonorrhoeae in a child.
Dossett, J H, Appelbaum, P C, Knapp, J S, Totten, P A
An 8-year-old boy developed proctitis. Rectal swabs yielded a Neisseria sp. that was repeatedly identified by API (Analytab Products, Plainview, N.Y.), Minitek (BBL Microbiology Systems,...
Mirrett, S, Reller, L B, Knapp, J S
Strains of Neisseria gonorrhoeae that failed to grow on Thayer-Martin (T-M) and Martin-Lewis (M-L) media accounted for 2.0% of isolates at the University of Colorado Hospital and its Venereal Disease...
Chen, K C, Culbertson, N J, Knapp, J S, Kenny, G E, Holmes, K K
A specific procedure has been developed for the detection of the first two enzymes involved in the arginine dihydrolase system and the detection of the decarboxylases of arginine, glutamic acid,...
The susceptibilities of 109 strains of Neisseria gonorrhoeae to penicillin G, tetracycline, amoxicillin-clavulanic acid, cefotetan, cefoxitin, ceftriaxone, ciprofloxacin, and fleroxacin were...
We determined the susceptibilities, by the agar dilution method, of 84 recent clinical isolates of Neisseria gonorrhoeae obtained from women with pelvic inflammatory disease in the United States to...
Knapp, J S, Washington, J A, Doyle, L J, Neal, S W, Parekh, M C, Rice, R J
Twenty-five isolates of beta-lactamase-negative strains of Neisseria gonorrhoeae exhibiting decreased susceptibilities to ciprofloxacin (MIC, > or = 0.125 microgram/ml) were isolated from men with...
Knapp, J S, Ohye, R, Neal, S W, Parekh, M C, Higa, H, Rice, R J
The susceptibilities of 37 penicillinase-producing strains of Neisseria gonorrhoeae (PPNG), isolated in Hawaii from December 1991 through January 1994, were determined to ciprofloxacin and ofloxacin,...
Morse, S A, Lysko, P G, McFarland, L, Knapp, J S, Sandstrom, E, Critchlow, C, ...
Loci designated penA, penB, and mtr contribute additively to penicillin G resistance in Neisseria gonorrhoeae; the mtr locus also confers resistance to hydrophobic dyes, detergents, and antibiotics,...
Sandstrom, E G, Knapp, J S, Buchanan, T B
A total of 224 strains were serogrouped by coagglutination (COA) and serotyped by protein I enzyme-linked immunosorbent assay (ELISA). Of these strains, 61 were from patients with disseminated...
Historical perspectives and identification of Neisseria and related species.
The pathogenic Neisseria spp., N. gonorrhoeae and N. meningitidis, have been studied extensively and rapid identification procedures have been designed to distinguish these species from the commensal...
Reevaluation of bacteriocinogeny in Neisseria gonorrhoeae.
Knapp, J S, Falkow, S, Holmes, K K
Bacteriocin typing has been described previously and proposed for typing gonococci. A survey has been made of 150 strains of N. gonorrhoeae from various places to determine the feasibility of a...
Serological classification of Neisseria gonorrhoeae with monoclonal antibodies.
Tam, M R, Buchanan, T M, Sandström, E G, Holmes, K K, Knapp, J S, Siadak, A W, ...
Hybrid cells producing monoclonal antibodies against antigens of Neisseria gonorrhoeae were obtained by the polyethylene glycol-mediated fusion of mouse myeloma cells and lymphocytes from mice...
Gonorrhea in the HIV era: a reversal in trends among men who have sex with men.
Fox, K K, Del Rio, C, Holmes, K K, Hook, E W, Judson, F N, Knapp, J S, ...
OBJECTIVES: Gonorrhea cases among men who have sex with men (MSM) declined in the early years of the HIV epidemic. We evaluated more recent trends in gonorrhea among MSM through the Centers for...
Pelvic inflammatory disease among patients in a public health practice: profile and outcomes.
Rice, R J, Coston, W A, Bhoomkar, A, Tambe, P B, Schmid, D S, Knapp, J S
Rice, R J, Bhullar, V, Mitchell, S H, Bullard, J, Knapp, J S
The in vitro susceptibilities of 45 recent clinical isolates of Chlamydia trachomatis obtained from women with asymptomatic genital tract infection, mucopurulent cervicitis, or pelvic inflammatory...
In vitro activity of a new fluoroquinolone, CP-99,219, against strains of Neisseria gonorrhoeae.
Knapp, J S, Neal, S W, Parekh, M C, Rice, R J
The susceptibilities of 216 strains of Neisseria gonorrhoeae to a new fluoroquinolone, CP-99,219 were determined. For strains for which the MICs of ciprofloxacin were < or = 0.06 microgram/ml, the...
Knapp, J S, Hale, J A, Neal, S W, Wintersheid, K, Rice, R J, Whittington, W L
The susceptibilities of 45 strains of Neisseria gonorrhoeae, including 25 strains susceptible to ciprofloxacin (MICs, < or = 0.06 microgram/ml) and 20 strains exhibiting decreased susceptibilities to...
Van Der Willigen, A H, Wagenvoort, J H, Schalla, W O, Knapp, J S, Boot, J M, Heeres-Weststrate, P L, ...
Uncomplicated urogenital and concomitant oropharyngeal gonorrhea in 424 male and female patients was treated in a randomized comparative study with 0.5 g of cefodizime (89 men and 54 women), 1 g of...
High-level tetracycline resistance in strains of Neisseria gonorrhoeae, Neisseria meningitidis, Kingella denitrificans, and Eikenella corrodens has recently been described. The resistance in each...
Knapp, J S, Johnson, S R, Zenilman, J M, Roberts, M C, Morse, S A
Similar to Neisseria gonorrhoeae, tetracycline-resistant isolates of N. meningitidis, Kingella denitrificans, and Eikenella corrodens contained 25.2-megadalton plasmids carrying the TetM determinant....
Van Der Willigen, A H, Van Der Hoek, J C, Wagenvoort, J H, Van Vliet, H J, Van Klingeren, B, Schalla, W O, ...
In a double-blind randomized study, 155 male patients with uncomplicated urethral gonorrhea were given 200 mg (one capsule with 200 mg and one capsule with placebo; n = 77) or 400 mg (two capsules...
Two highly tetracycline-resistant, beta-lactamase-producing Neisseria gonorrhoeae strains were used as donors for conjugation with Neisseria meningitidis and commensal Neisseria species. We found...
Knapp, J S, Back, A F, Babst, A F, Taylor, D, Rice, R J
We determined the in vitro susceptibilities of 54 isolates of Haemophilus ducreyi from Thailand (29 isolates) and San Francisco (25 isolates) to penicillin G, tetracycline, amoxicillin-clavulanic...
Antimicrobial susceptibilities of Neisseria gonorrhoeae strains isolated in Surabaya, Indonesia.
Joesoef, M R, Knapp, J S, Idajadi, A, Linnan, M, Barakbah, Y, Kamboji, A, ...
Until recently, the only common strains of antimicrobial agent-resistant Neisseria gonorrhoeae detected in Indonesia were penicillinase-producing N. gonorrhoeae (PPNG) strains. Despite the spread of...
Motley, M, Sarafian, S K, Knapp, J S, Zaidi, A A, Schmid, G
We determined the susceptibilities of 94 strains of Haemophilus ducreyi isolated in various municipalities in the United States between 1982 and 1989 to the following antimicrobial agents:...
Immunoglobulin A1 (IgA1) proteases are extracellular bacterial proteolytic enzymes which correlate with virulence in several species of human pathogens. We report that Neisseria gonorrhoeae produced...
Tenover, F C, Knapp, J S, Patton, C, Plorde, J J
A chemically defined medium developed for Neisseria gonorrhoeae was modified to support the growth of Campylobacter jejuni and Campylobacter coli. A total of 76 isolates of C. jejuni and 14 isolates...
Anaerobic growth of Neisseria gonorrhoeae coupled to nitrite reduction.
A total of 204 Neisseria gonorrhoeae strains, including 39 penicillinase-producing strains, representing 64 distinct auxotype and serovar classes were tested for their ability to grow anaerobically...
Beebe, J L, Rau, M P, Flageolle, S, Calhoon, B, Knapp, J S
To determine the accuracy of the Syva (Palo Alto, Calif.) direct fluorescent-antibody (DFA) test in comparison with the Gen-Probe (San Diego, Calif.) Accuprobe culture confirmation test, we tested...
Panel of reference strains for evaluating serologic reagents used to identify gonococci.
Evins, G M, Pigott, N E, Knapp, J S, DeWitt, W E
A panel of strains for evaluating Neisseria gonorrhoeae serologic reagents was developed. The strains selected for the panel were antigenically diverse and representative of strains isolated...
Certain strains of Neisseria gonorrhoeae have been used by numerous investigators to develop serologic classification systems. Some of these strains have been used by investigators to study...
Prevalence and persistence of Neisseria cinerea and other Neisseria spp. in adults.
Neisseria cinerea is a commensal Neisseria sp. which was first described in 1906 but was subsequently misclassified as a subtype of Branhamella catarrhalis. N. cinerea resembles Neisseria gonorrhoeae...
Jones, R N, Gavan, T L, Thornsberry, C, Fuchs, P C, Gerlach, E H, Knapp, J S, ...
A six-laboratory study developed a standardized method for determining the susceptibilities of Neisseria gonorrhoeae strains to penicillin, tetracycline, spectinomycin, and ceftriaxone. Three quality...
Del Rio, C, Stephens, D S, Knapp, J S, Rice, R J, Schalla, W O
We studied a previously healthy 20-year-old woman who presented with gonococcal meningitis. The gonococcal isolate, HT-1, was prototrophic by auxotyping, was protein I serovar IB-1, and agglutinated...
Production of 14C-labeled gas in BACTEC Neisseria Differentiation kits by Neisseria cinerea.
Boyce, J M, Mitchell, E B, Knapp, J S, Buttke, T M
Six strains of Neisseria cinerea were tested in BACTEC Neisseria Differentiation kits (Johnston Laboratories, Inc., Towson, Md.), and all yielded positive glucose growth indices and negative maltose...