J. S. McDougal

Publication List Details

Period

1997 - 1997

Number

22

Co-Authors

The site of antiviral action of 3-nitrosobenzamide on the infectivity process of human immunodeficiency virus in human lymphocytes.

Rice, W G, Schaeffer, C A, Graham, L, Bu, M, McDougal, J S, Orloff, S L, ...

The C-nitroso compound 3-nitrosobenzamide, which has been shown to remove zinc from the retroviral-type zinc finger of p7NC nucleocapsid proteins, inhibits acute infection of human immunodeficiency...

Mechanisms of human immunodeficiency virus Type 1 (HIV-1) neutralization: irreversible inactivation of infectivity by anti-HIV-1 antibody.

McDougal, J S, Kennedy, M S, Orloff, S L, Nicholson, J K, Spira, T J

An assay for the neutralization of human immunodeficiency virus type 1 (HIV-1) is described in which the reduction in infectious titer of HIV-1 after preincubation at 37 degrees C with...

Inactivation of human T-lymphotropic virus type III/lymphadenopathy-associated virus by formaldehyde-based reagents.

Martin, L S, Loskoski, S L, McDougal, J S

Neutral buffered Formalin, a fixative used in most pathology laboratories, was found to inactivate human T-lymphotropic virus type III/lymphadenopathy-associated virus. Preparations containing this...

Two mechanisms of soluble CD4 (sCD4)-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) infectivity and their relation to primary HIV-1 isolates with reduced sensitivity to sCD4.

Orloff, S L, Kennedy, M S, Belperron, A A, Maddon, P J, McDougal, J S

Two assays for measuring inhibition of human immunodeficiency virus type 1 (HIV-1) infection by soluble CD4 (sCD4) are described. Experiments in which sCD4, HIV-1, and cell concentrations and...

Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4.

Skinner, M A, Langlois, A J, McDanal, C B, McDougal, J S, Bolognesi, D P, Matthews, T J

Animals immunized with the human immunodeficiency virus type 1 gp160 glycoprotein or certain recombinant envelope components develop potent virus-neutralizing activity. This activity is principally...

Binding of immunoglobulin G aggregates and immune complexes in human sera to Staphylococci containing protein A.

McDougal, J S, Redecha, P B, Inman, R D, Christian, C L

Using the Cowan I strain of Staphylococcus aureus, we compared the binding properties of human monomeric immunoglobulin (Ig)G and oligomeric or complexed IgG. Heat-aggregated IgG served as a model...

Thermal inactivation of the acquired immunodeficiency syndrome virus, human T lymphotropic virus-III/lymphadenopathy-associated virus, with special reference to antihemophilic factor.

McDougal, J S, Martin, L S, Cort, S P, Mozen, M, Heldebrant, C M, Evatt, B L

The virus that causes the acquired immunodeficiency syndrome (AIDS), human T lymphotropic virus/lymphadenopathy-associated virus (HTLV-III/LAV), was incubated at temperatures from 37 degrees to 60...

Immunoregulatory subsets of the T helper and T suppressor cell populations in homosexual men with chronic unexplained lymphadenopathy.

Nicholson, J K, McDougal, J S, Spira, T J, Cross, G D, Jones, B M, Reinherz, E L

Unexplained, generalized lymphadenopathy in homosexual men, which can be a prodrome to the acquired immunodeficiency syndrome, is associated with impaired cell-mediated immunity, a low ratio of T...

Antibody response to human immunodeficiency virus in homosexual men. Relation of antibody specificity, titer, and isotype to clinical status, severity of immunodeficiency, and disease progression.

McDougal, J S, Kennedy, M S, Nicholson, J K, Spira, T J, Jaffe, H W, Kaplan, J E, ...

The titers and isotypes of antibodies to specific proteins of the human immunodeficiency virus were determined by Western blot analysis of sera from 107 homosexual men. Antibody titers were generally...

The site of antiviral action of 3-nitrosobenzamide on the infectivity process of human immunodeficiency virus in human lymphocytes.

Rice, W G, Schaeffer, C A, Graham, L, Bu, M, McDougal, J S, Orloff, S L, ...

The C-nitroso compound 3-nitrosobenzamide, which has been shown to remove zinc from the retroviral-type zinc finger of p7NC nucleocapsid proteins, inhibits acute infection of human immunodeficiency...

Mechanisms of human immunodeficiency virus Type 1 (HIV-1) neutralization: irreversible inactivation of infectivity by anti-HIV-1 antibody.

McDougal, J S, Kennedy, M S, Orloff, S L, Nicholson, J K, Spira, T J

An assay for the neutralization of human immunodeficiency virus type 1 (HIV-1) is described in which the reduction in infectious titer of HIV-1 after preincubation at 37 degrees C with...

Inactivation of human T-lymphotropic virus type III/lymphadenopathy-associated virus by formaldehyde-based reagents.

Martin, L S, Loskoski, S L, McDougal, J S

Neutral buffered Formalin, a fixative used in most pathology laboratories, was found to inactivate human T-lymphotropic virus type III/lymphadenopathy-associated virus. Preparations containing this...

Two mechanisms of soluble CD4 (sCD4)-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) infectivity and their relation to primary HIV-1 isolates with reduced sensitivity to sCD4.

Orloff, S L, Kennedy, M S, Belperron, A A, Maddon, P J, McDougal, J S

Two assays for measuring inhibition of human immunodeficiency virus type 1 (HIV-1) infection by soluble CD4 (sCD4) are described. Experiments in which sCD4, HIV-1, and cell concentrations and...

Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4.

Skinner, M A, Langlois, A J, McDanal, C B, McDougal, J S, Bolognesi, D P, Matthews, T J

Animals immunized with the human immunodeficiency virus type 1 gp160 glycoprotein or certain recombinant envelope components develop potent virus-neutralizing activity. This activity is principally...

Binding of immunoglobulin G aggregates and immune complexes in human sera to Staphylococci containing protein A.

McDougal, J S, Redecha, P B, Inman, R D, Christian, C L

Using the Cowan I strain of Staphylococcus aureus, we compared the binding properties of human monomeric immunoglobulin (Ig)G and oligomeric or complexed IgG. Heat-aggregated IgG served as a model...

Thermal inactivation of the acquired immunodeficiency syndrome virus, human T lymphotropic virus-III/lymphadenopathy-associated virus, with special reference to antihemophilic factor.

McDougal, J S, Martin, L S, Cort, S P, Mozen, M, Heldebrant, C M, Evatt, B L

The virus that causes the acquired immunodeficiency syndrome (AIDS), human T lymphotropic virus/lymphadenopathy-associated virus (HTLV-III/LAV), was incubated at temperatures from 37 degrees to 60...

Immunoregulatory subsets of the T helper and T suppressor cell populations in homosexual men with chronic unexplained lymphadenopathy.

Nicholson, J K, McDougal, J S, Spira, T J, Cross, G D, Jones, B M, Reinherz, E L

Unexplained, generalized lymphadenopathy in homosexual men, which can be a prodrome to the acquired immunodeficiency syndrome, is associated with impaired cell-mediated immunity, a low ratio of T...

Antibody response to human immunodeficiency virus in homosexual men. Relation of antibody specificity, titer, and isotype to clinical status, severity of immunodeficiency, and disease progression.

McDougal, J S, Kennedy, M S, Nicholson, J K, Spira, T J, Jaffe, H W, Kaplan, J E, ...

The titers and isotypes of antibodies to specific proteins of the human immunodeficiency virus were determined by Western blot analysis of sera from 107 homosexual men. Antibody titers were generally...

Human markers for IgG2 and IgG4 appear to be on the same molecule in the chimpanzee.

Black, C M, McDougal, J S, Evatt, B L, Reimer, C B

It has been reported that all four immunoglobulin G (IgG) subclasses present in human serum are also present in chimpanzee serum, as detected with antibodies specific for the human IgG subclasses. We...

Dynamics of mononuclear phagocyte system Fc receptor function in systemic lupus erythematosus. Relation to disease activity and circulating immune complexes.

Kimberly, R P, Parris, T M, Inman, R D, McDougal, J S

Seventeen pairs of longitudinal studies of mononuclear phagocyte system (MPS) Fc receptor function in 15 patients with systemic lupus were performed to explore the dynamic range of Fc receptor...

Alternative Algorithms for Human Immunodeficiency Virus Infection Diagnosis Using Tests That Are Licensed in the United Statesâ–¿

Owen, S. M., Yang, C., Spira, T., Ou, C. Y., Pau, C. P., Parekh, B. S., ...

Serodiagnosis of human immunodeficiency virus (HIV) infection in the United States has traditionally relied on a sequential two-test algorithm: an initial screen with an enzyme immunoassay (EIA) and...