J. Salmon

Discovery of 4-[3-(trans-3-dimethylaminocyclobutyl)-1H-indol-5-ylmethyl]- (4S)-oxazolidin-2-one (4991W93), a 5HT1B/1D receptor partial agonist and a potent inhibitor of electrically induced plasma extravasation (2001)

Jandu, K.S., Barrett, V., Brockwell, M., Cambridge, D., Farrant, D.R., Foster, C., ...

Utilizing a pharmacophoric model of binding of 3-(2-aminoethyl)indoles to 5HT1B/1D receptors, we identified the 3-aminocyclobutyl group as a potential ethylamine isostere. A novel multidimensional...