UCHL1 is a Parkinson's disease susceptibility gene (2004)
Maraganore, D. M., Lesnick, T.G., Elbaz, A., Gasser, T., Kruger, R., ...
The reported inverse association between the S18Y variant of the ubiquitin carboxy-terminal hydrolase L1 (UCHL1) gene and Parkinson's disease (PD) has strong biological plausibility. If confirmed,...
Satoh, J, Seino, H, Abo, T, Tanaka, S, Shintani, S, Ohta, S, ...
We previously reported that administration of a streptococcal preparation (OK-432) inhibited insulitis and development of autoimmune diabetes in nonobese diabetic (NOD) mice and BB rats as animals...
Shimizu, F, Satoh, J, Tada, M, Kumagai, K
A rounding cell-forming--GC strain, which is a variant of a syncytial giant cell-forming herpes simplex virus (+GC Miyama strain), was highly attenuated for Swiss, BALB/c nu/nu, and nu/+ mice,...
Essani, K, Satoh, J, Prabhakar, B S, McClintock, P R, Notkins, A L
We have recently isolated and characterized a human monoclonal autoantibody, MOR-h1 (multiple organ-reactive human 1), that reacts with antigens in multiple organs and have shown that this antibody...
Satoh, J, Essani, K, McClintock, P R, Notkins, A L
By fusing peripheral leukocytes from a patient with insulin-dependent diabetes with mouse myeloma cells, a heterohybridoma was isolated that, for over one year, has secreted a human monoclonal...
Ikehata, F, Satoh, J, Nata, K, Tohgo, A, Nakazawa, T, Kato, I, ...
Cyclic ADP-ribose (cADPR) has been shown to be a mediator for intracellular Ca2+ mobilization for insulin secretion by glucose in pancreatic beta cells, and CD38 shows both ADP-ribosyl cyclase to...
Satoh, J, Seino, H, Abo, T, Tanaka, S, Shintani, S, Ohta, S, ...
We previously reported that administration of a streptococcal preparation (OK-432) inhibited insulitis and development of autoimmune diabetes in nonobese diabetic (NOD) mice and BB rats as animals...
Shimizu, F, Satoh, J, Tada, M, Kumagai, K
A rounding cell-forming--GC strain, which is a variant of a syncytial giant cell-forming herpes simplex virus (+GC Miyama strain), was highly attenuated for Swiss, BALB/c nu/nu, and nu/+ mice,...
Essani, K, Satoh, J, Prabhakar, B S, McClintock, P R, Notkins, A L
We have recently isolated and characterized a human monoclonal autoantibody, MOR-h1 (multiple organ-reactive human 1), that reacts with antigens in multiple organs and have shown that this antibody...
Satoh, J, Essani, K, McClintock, P R, Notkins, A L
By fusing peripheral leukocytes from a patient with insulin-dependent diabetes with mouse myeloma cells, a heterohybridoma was isolated that, for over one year, has secreted a human monoclonal...
Ikehata, F, Satoh, J, Nata, K, Tohgo, A, Nakazawa, T, Kato, I, ...
Cyclic ADP-ribose (cADPR) has been shown to be a mediator for intracellular Ca2+ mobilization for insulin secretion by glucose in pancreatic beta cells, and CD38 shows both ADP-ribosyl cyclase to...
Satoh, J, Miyasaka, N, Yamada, T, Nishido, T, Okuda, M, Kuroiwa, T, ...
The central nervous system is often affected in Wegener's granulomatosis (WG), but massive cerebral infarction due to occlusion of branches of the anterior cerebral arteries (ACA) by granulomatous...
The twitcher mouse. An alteration of the unmyelinated fibers in the PNS.
Kobayashi, S., Katayama, M., Satoh, J., Suzuki, K., Suzuki, K.
The twitcher is an authentic murine model of globoid cell leukodystrophy (GLD) in man. Extensive demyelination of the central and peripheral nervous systems (CNS and PNS) characterizes the...
Seino, H, Satoh, J, Shintani, S, Takahashi, K, Zhu, X P, Masuda, T, ...
We have recently reported that systemic and chronic administration of recombinant tumour necrosis factor alpha (TNF-alpha), as well as streptococcal preparation (OK-432), inhibits development of...