J. Schneider-Schaulies

Receptor usage and differential downregulation of CD46 by measles virus wild-type and vaccine strains.

Schneider-Schaulies, J, Schnorr, J J, Brinckmann, U, Dunster, L M, Baczko, K, Liebert, U G, ...

Recently, two cell surface molecules, CD46 and moesin, have been found to be functionally associated with measles virus (MV) infectivity of cells. We investigated the receptor usage of MV wild-type,...

Physical association of moesin and CD46 as a receptor complex for measles virus.

Schneider-Schaulies, J, Dunster, L M, Schwartz-Albiez, R, Krohne, G, Ter Meulen, V

Recently, two cellular membrane proteins, the membrane cofactor protein CD46 and the membrane-organizing external spike protein, moesin, have been identified to be functionally associated with...

Differential downregulation of CD46 by measles virus strains.

Schneider-Schaulies, J, Dunster, L M, Kobune, F, Rima, B, Ter Meulen, V

Recently, we found that several lymphotropic wild-type isolates of measles virus (MV) did not lead to the downregulation of CD46 following infection. We hypothesized that either the site of virus...

Receptor (CD46) modulation and complement-mediated lysis of uninfected cells after contact with measles virus-infected cells.

Schneider-Schaulies, J, Schnorr, J J, Schlender, J, Dunster, L M, Schneider-Schaulies, S, Ter Meulen, V

Recently, it has been observed that the infection of human target cells with certain measles virus (MV) strains leads to the downregulation of the major MV receptor CD46. Here we report that CD46...

CD9, a tetraspan transmembrane protein, renders cells susceptible to canine distemper virus.

Löffler, S, Lottspeich, F, Lanza, F, Azorsa, D O, Ter Meulen, V, Schneider-Schaulies, J

Canine distemper virus (CDV), a lymphotropic and neurotropic negative-stranded RNA virus of the Morbillivirus genus, causes a life-threatening disease in several carnivores, including domestic dogs....

CD46 expression does not overcome the intracellular block of measles virus replication in transgenic rats.

Niewiesk, S, Schneider-Schaulies, J, Ohnimus, H, Jassoy, C, Schneider-Schaulies, S, Diamond, L, ...

The study of measles pathogenesis and the testing of improved vaccine candidates is hampered by the lack of a small animal model which is susceptible to infection by the intranasal route. With the...

Binding of measles virus to membrane cofactor protein (CD46): importance of disulfide bonds and N-glycans for the receptor function.

Maisner, A, Schneider-Schaulies, J, Liszewski, M K, Atkinson, J P, Herrler, G

Two cellular proteins, membrane cofactor protein (MCP) and moesin, were reported recently to be functionally associated with the initiation of a measles virus infection. We have analyzed the...

Cell type-specific MxA-mediated inhibition of measles virus transcription in human brain cells.

Schneider-Schaulies, S, Schneider-Schaulies, J, Schuster, A, Bayer, M, Pavlovic, J, Ter Meulen, V

Measles virus (MV)-specific transcription in human brain cells is characterized by particularly low abundances of the distal mRNAs encoding the MV envelope proteins. Similar transcriptional...

Spontaneous and differentiation-dependent regulation of measles virus gene expression in human glial cells.

Schneider-Schaulies, S, Schneider-Schaulies, J, Bayer, M, Löffler, S, Ter Meulen, V

The expression of measles virus (MV) in six different permanent human glioma cell lines (D-54, U-251, U-138, U-105, U-373, and D-32) was analyzed. Although all cell lines were permissive for...

Receptor usage and differential downregulation of CD46 by measles virus wild-type and vaccine strains.

Schneider-Schaulies, J, Schnorr, J J, Brinckmann, U, Dunster, L M, Baczko, K, Liebert, U G, ...

Recently, two cell surface molecules, CD46 and moesin, have been found to be functionally associated with measles virus (MV) infectivity of cells. We investigated the receptor usage of MV wild-type,...

Physical association of moesin and CD46 as a receptor complex for measles virus.

Schneider-Schaulies, J, Dunster, L M, Schwartz-Albiez, R, Krohne, G, Ter Meulen, V

Recently, two cellular membrane proteins, the membrane cofactor protein CD46 and the membrane-organizing external spike protein, moesin, have been identified to be functionally associated with...

Differential downregulation of CD46 by measles virus strains.

Schneider-Schaulies, J, Dunster, L M, Kobune, F, Rima, B, Ter Meulen, V

Recently, we found that several lymphotropic wild-type isolates of measles virus (MV) did not lead to the downregulation of CD46 following infection. We hypothesized that either the site of virus...

Receptor (CD46) modulation and complement-mediated lysis of uninfected cells after contact with measles virus-infected cells.

Schneider-Schaulies, J, Schnorr, J J, Schlender, J, Dunster, L M, Schneider-Schaulies, S, Ter Meulen, V

Recently, it has been observed that the infection of human target cells with certain measles virus (MV) strains leads to the downregulation of the major MV receptor CD46. Here we report that CD46...

CD9, a tetraspan transmembrane protein, renders cells susceptible to canine distemper virus.

Löffler, S, Lottspeich, F, Lanza, F, Azorsa, D O, Ter Meulen, V, Schneider-Schaulies, J

Canine distemper virus (CDV), a lymphotropic and neurotropic negative-stranded RNA virus of the Morbillivirus genus, causes a life-threatening disease in several carnivores, including domestic dogs....

CD46 expression does not overcome the intracellular block of measles virus replication in transgenic rats.

Niewiesk, S, Schneider-Schaulies, J, Ohnimus, H, Jassoy, C, Schneider-Schaulies, S, Diamond, L, ...

The study of measles pathogenesis and the testing of improved vaccine candidates is hampered by the lack of a small animal model which is susceptible to infection by the intranasal route. With the...

Binding of measles virus to membrane cofactor protein (CD46): importance of disulfide bonds and N-glycans for the receptor function.

Maisner, A, Schneider-Schaulies, J, Liszewski, M K, Atkinson, J P, Herrler, G

Two cellular proteins, membrane cofactor protein (MCP) and moesin, were reported recently to be functionally associated with the initiation of a measles virus infection. We have analyzed the...

Cell type-specific MxA-mediated inhibition of measles virus transcription in human brain cells.

Schneider-Schaulies, S, Schneider-Schaulies, J, Schuster, A, Bayer, M, Pavlovic, J, Ter Meulen, V

Measles virus (MV)-specific transcription in human brain cells is characterized by particularly low abundances of the distal mRNAs encoding the MV envelope proteins. Similar transcriptional...

Spontaneous and differentiation-dependent regulation of measles virus gene expression in human glial cells.

Schneider-Schaulies, S, Schneider-Schaulies, J, Bayer, M, Löffler, S, Ter Meulen, V

The expression of measles virus (MV) in six different permanent human glioma cell lines (D-54, U-251, U-138, U-105, U-373, and D-32) was analyzed. Although all cell lines were permissive for...