Methods for the identification of inhibitors of asparagine synthase as antibiotics (2005)
Lo, CSC, Montenegro-Chamorro, MV, Frank, S, Darveaux, B, Mahanty, S, Heiniger, R, ...
The present inventors have discovered that Asparagine Synthase is essential for fungal pathogenicity. Specifically, the inhibition of Asparagine Synthase gene expression in fungi results in no signs...
Methods for the identification of inhibitors of threonine synthase as antibiotics (2004)
Adachi, K, DeZwaan, T, Lo, CSC, Montenegro-Chamorro, MV, Frank, S, Darveaux, B, ...
The present inventors have discovered that Threonine synthase is essential for fungal pathogenicity. Specifically, the inhibition of Threonine synthase gene expression in fungi results in no signs of...
Methods for the identification of inhibitors of 3-iosopropylmalate dehydratase as antibiotics (2004)
Hamer, L, Adachi, K, DeZwaan, T, Lo, CSC, Montenegro-Chamorro, MV, Frank, S, ...
The present inventors have discovered that 3-Isopropylmalate dehydratase is essential for fungal pathogenicity. Specifically, the inhibition of 3-Isopropylmalate dehydratase gene expression in fungi...
Methods for the identification of inhibitors of .alpha.-aminoadipate reductase as antibiotics (2004)
Tanzer, T, Tanzer, MM, Hamer, L, Adachi, K, DeZwaan, T, Lo, CSC, ...
The present inventors have discovered that .alpha.-Aminoadipate Reductase is essential for fungal pathogenicity. Specifically, the inhibition of .alpha.-Aminoadipate Reductase gene expression in...
Methods for the identification of inhibitors of 5-aminolevulinate synthase as antibiotics (2004)
DeZwaan, T, Lo, CSC, Montenegro-Chamorro, MV, Frank, S, Darveaux, B, Mahanty, S, ...
The present inventors have discovered that 5-Aminolevulinate synthase is essential for fungal pathogenicity. Specifically, the inhibition of 5-Aminolevulinate synthase gene expression in fungi...
Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements (2003)
Pui, C.H., Chessells, J.M., Camitta, B., Baruchel, A., Biondi, A., Boyett, J.M., ...
To assess the clinical heterogeneity among patients with acute lymphoblastic leukemia (ALL) and various 11q23 abnormalities, we analyzed data on 497 infants, children and young adults treated between...
Methods for the identification of inhibitors of homocitrate synthase as antibiotics (2003)
Shuster, J, Tanzer, T, Hamer, L, Adachi, K, DeZwaan, T, Lo, CSC, ...
The present inventors have discovered that homocitrate synthase is essential for fungal pathogenicity. Specifically, the inhibition of homocitrate synthase gene expression in fungi results in no...
ADR1-mediated regulation of ADH2 requires an inverted repeat sequence.
Shuster, J, Yu, J, Cox, D, Chan, R V, Smith, M, Young, E
DNA sequence analysis of wild-type and mutant ADH2 loci suggested that two unusual features 5' of the promoter, a 22-base-pair perfect dyad sequence and a (dA)20 tract, were important for regulation...
Tha, S P, Shuster, J, Goldsmith, H L
The expressions derived in the previous paper for the respective normal, F3, and shear forces, Fshear, acting along and perpendicular to the axis of a doublet of rigid spheres, were used to determine...
ADR1-mediated regulation of ADH2 requires an inverted repeat sequence.
Shuster, J, Yu, J, Cox, D, Chan, R V, Smith, M, Young, E
DNA sequence analysis of wild-type and mutant ADH2 loci suggested that two unusual features 5' of the promoter, a 22-base-pair perfect dyad sequence and a (dA)20 tract, were important for regulation...
Tha, S P, Shuster, J, Goldsmith, H L
The expressions derived in the previous paper for the respective normal, F3, and shear forces, Fshear, acting along and perpendicular to the axis of a doublet of rigid spheres, were used to determine...
Tsoukas, C., Gervais, F., Fuks, A., Guttmann, R. D., Strawczynski, H., Shuster, J., ...
The occurrence of the acquired immune deficiency syndrome (AIDS) in patients with hemophilia has suggested that an infectious agent transmitted through the frequent use of pooled blood products could...
Studies on a unique diagnostic serum globulin in papular mucinosis (lichen myxedematosus)
James, K., Fudenberg, H., Epstein, W. L., Shuster, J.
An abnormal γ-globulin present in the sera of five patients with papular mucinosis (PM) (lichen myxedematosus) appears to be characteristic of the disease. The PM protein is closely related to...
Munchausen Syndrome: A Cause of Pyrexia of Unknown Origin
Thompson, G. W., Shuster, J., Williams, R. L., Kaye, Michael
Isolation of human tumour-specific antigens associated with beta2 microglobulin.
Thomson, D. M., Rauch, J. E., Weatherhead, J. C., Friedlander, P., O'Connor, R., Grosser, N., ...
In the present study the tube LAI assay was used to monitor the isolation of the TSA of 4 different types of human cancers. Each tumour antigen was found to be specific for tumours arising in the...