Comparison of micron- and nanoparticle deposition patterns in a realistic human nasal cavity (2009)
Wang, S, Inthavong, K, Wen, J, Tu, J, Xue, C
Knowledge regarding particle deposition processes in the nasal cavity is important in aerosol therapy and inhalation toxicology applications. This paper presents a comparative study of the deposition...
Numerical simulations for detailed airflow dynamics in a human nasal cavity (2008)
Wen, J, Inthavong, K, Tu, J, Wang, S
Nasal physiology is dependent on the physical structure of the nose. Individual aspects of the nasal cavity such as the geometry and flow rate collectively affect nasal function such as the...
Inthavong, K, Tian, Z, Tu, J, Yang, W
Experimental images from particle/droplet image analyser (PDIA) and particle image velocimetry (PIV) imaging techniques of particle formation from a nasal spray device were taken to determine...
Mohanarangam, K, Tu, J, Chen, L
Numerical simulations were performed for dilute gas-particle flows over two-dimensional turbulent backward-facing step geometry to examine the effects of step heights on turbulent separated flow with...
Mohanarangam, K, Tian, Z, Tu, J
A numerical investigation into the physical characteristics of dilute gas--particle flows over a square-sectioned 90° bend is reported. The modified Eulerian two-fluid model is employed to predict...
Numerical simulation of the migration of hot gases in open vertical shaft (2008)
The problem associated with the migration of hot gases in open vertical shaft has been numerically investigated. Model predictions based on the same experimental conditions have shown to yield good...
Three-dimensional two-fluid model and population balance equation is presented to treat the complex hydrodynamics and thermomechanical processes under various bubbly flow conditions. The class...
Tian, Z, Inthavong, K, Tu, J, Yeoh, G
This paper presents a numerical study of a dilute gas-particle flow in a 90° bend by employing a Lagrangian particle-tracking model combined with a particle-wall collision model and a stochastic...
Fundamental consideration of wall heat partition of vertical subcooled boiling flows (2008)
Yeoh, G, Cheung, S, Tu, J, Ho, M
Improved wall heat flux partitioning accounting sliding bubbles and a mechanistic model that incorporates the fundamental consideration of bubble frequency during low-pressure subcooled flow boiling...
Bubble departure frequency in forced convective subcooled boiling flow (2008)
Situ, R, Ishii, M, Hibiki, T, Tu, J, Yeoh, G, Mori, M
Forced convective subcooled boiling flow experiments were conducted in a vertical upward annular channel. Water was used as the testing fluid, and the tests were performed at atmospheric pressure. A...
The effect of a longitudinally oscillating cylinder on the two-dimensionality of flow around a downstream cylinder is studied based on a two-point correlation measured using two hot-wires. The...
Numerical study of fibre deposition in a human nasal cavity (2008)
Inthavong, K, Wen, J, Tian, Z, Tu, J
Nasal physiology is dependent on the physical structure of the nose. Individual aspects of the nasal cavity such as the geometry and flow rate collectively affect nasal function such as the...
Population balance models for subcooled boiling flows (2008)
Purpose: This study aims to examine both the population balance approach based on the MUltiple SIze Group (MUSIG) model and the average bubble number density transport equation (ABND) model for 3D,...
Inhalation of toxic and therapeutic particles in a human nasal cavity (2008)
The reconstruction of the nasal cavity from computed tomography (CT) scans to a computational model was performed in order to (i) analyse the air flow field and (ii) particle dynamics. The scans were...
We investigate the behaviour of the pulsatile blood flow in a stenosed right coronary artery with a bypass graft. The human blood is assumed as a non-Newtonian fluid and its viscous behaviour is...
Deposition of inhaled wood dust in the nasal cavity (2007)
Detailed deposition patterns of inhaled wood dust in an anatomically accurate nasal cavity were investigated using computational fluid dynamics (CFD) techniques. Three wood dusts, pine dust, heavy...
Reconstruction of blood flow patterns in a stenosed and normal carotid bifurcation (2007)
Cheung, C, Ding, S, Tu, J, Ye, Y, Reutens, D, Beare, R
Abstract not available.
Two population balance approaches based on the MUltiple-SIze-Group (MUSIG) model and one-group average bubble number density (ABND) model for handling the bubble size distribution of gas-liquid...
Numerical studies of indoor airflow and particle dispersion by large Eddy simulation (2007)
Tian, Z, Tu, J, Yeoh, G, Yuen, R
The indoor airflow and contaminant particle concentration in two geometrically different rooms have been investigated using the Large Eddy Simulation (LES) technique based on Renormalization Group...
Two-fluid model for particle-turbulence interaction in a backward-facing step (2007)
Particle-turbulence interaction for dilute gas-particle flows over a backward-facing step geometry is numerically investigated. An Eulerian two-fluid model with additional turbulence transport...
Numerical modelling and validation of gas-particle flow in an in-line tube bank (2007)
This paper presents a numerical study of dilute gas-particle flows in an in-line tube bank. The physical characteristics of the particle-wall collisions and their contributions to particle phase flow...
To model the spatial evolution of the geometrical structure of the gas bubbles in isothermal vertical bubbly flow conditions, the population balance approach has been employed and merged with the...
Numerical study of the effect of trailing edge bluntness on highly turbulent hydrofoil flow (2007)
Turbulent trailing edge flow over control surfaces continues to be of interest to many designers and researchers alike due to the associated complex and adverse phenomena. In this study a two...
CFD studies of indoor airflow and contaminant particle transportation (2007)
This article presents a numerical study of indoor airflows and contaminant particle transportation in three ventilated rooms. The realizable k - epsilon model is employed to model the air-phase...
Computational fluid graphics - a practical approach (2007)
A senior level undergraduate and graduate textbook for a wide audience of engineering students taking a first course in CFD or Computer Aided Engineering. Fully course matched, with the most...
Geometric model generation for CFD simulation of blood and air flows (2007)
A new adaptive algorithm is developed for the reconstruction of geometric models of carotid arteries and human airways from CT images. Based on the patient-specific geometric models, Computational...
A generalised CFD learning and prediction system (2007)
An expert system that learns data from Computational Fluid Dynamics (CFD) simulations and presents it to non-expert users of CFDs to make informed design decisions is proposed. The system is...
A numerical study of spray particle deposition in a human nasal cavity (2006)
Inthavong, K, Tian, Z, Li, H, Tu, J, Yang, W, Xue, C, ...
Particle depositional studies from nasal sprays are important for efficient drug delivery. The main influences on deposition involve the nasal cavity geometry and the nasal spray device of which its...
Flow instability prediction in low-pressure subcooled boiling flows using CFD codes (2006)
A proposed model for low pressure subcooled boiling flow was incorporated into the safety reactor code RELAP5/MOD3.2 to enhance the performance of the reactor code to predict the occurrence of the...
On the numerical study of contaminant particle concentration in indoor airflow (2006)
Tian, Z, Tu, J, Yeoh, G, Yuen, R
The application of three turbulence models-standard k-epsilon, re-normalization group (RNG) k-epsilon and RNG-based large eddy simulation (LES) model-to simulate indoor contaminant particle...
Numerical modelling of bubbly flows with and without heat and mass transfer (2006)
In this paper, modelling gas-liquid bubbly flows is achieved by the introduction of a population balance equation combined with the three-dimensional two-fluid model. For gas-liquid bubbly flows...
Two-fluid and population balanace models for subcooled boiling flow (2006)
Population balance equations combined with a three-dimensional two-fluid model are employed to predict subcooled boiling flow at low pressure in a vertical annular channel. The MUSIG...
Abu-Hijleh, B, Tu, J, Subic, A
Computational fluid dynamics (CFD) simulation was used to Study the effect of modifying the inlet and Outlet of an elliptical rotor-casing assembly at two different rotor aspect ratios. The...
Flow and particle deposition patterns in a realistic human double bifurcation airway model (2006)
Velocity profiles, local deposition efficiencies (DE), and deposition patterns of aerosol particles in the first three generations (i.e., double bifurcations) of an airway model have been simulated...
Li, H, Tu, J, Subic, A, Abu-Hijleh, B
The performance of a twin-screw supercharger is influenced more by the internal air leakages than by any other thermo-fluid aspect of its behaviour. The distribution of leakage through the various...
www.niss.org A Framework for Validation of Computer Models ∗ (2005)
M. J. Bayarri, J. O. Berger, R. Paulo, J. Sacks, J. A. Cafeo, J. Cavendish, ...
In this paper, we present a framework that enables computer model evaluation oriented towards answering the question: Does the computer model adequately represent reality? The proposed validation...
www.niss.org Bayesian Validation of a Computer Model for Vehicle (2005)
M. J. Bayarri, J. O. Berger, M. C. Kennedy, A. Kottas, R. Paulo, J. Sacks, ...
A key question in evaluation of computer models is Does the computer model adequately represent reality? A complete Bayesian approach to answering this question is developed for the challenging...
On population balance approach for subcooled boiling flow prediction (2005)
Tu, J, Yeoh, G, Park, G, Kim, M
The capability of using the population balance approach combined with a three-dimensional two-fluid model for predicting subcooled boiling flow is investigated. Experiments were conducted to study...
Computation of flow behind three side-by-side cylinders of unequal/equal spacing (2005)
Chen, L, Tu, J, Zhou, Y, Virahsawmy, H, McGillivray, I
This paper aims to simulate unstable gap flows of three side-by-side cylinders unequally/equally spaced at T1/d = 1.5 and T2/d = 1.6 in a uniform cross flow (Re=300). The simulation is carried out...
Numerical simulation and validation of dilute gas-particle flow over a backward-facing step (2005)
The physical characteristics of dilute gas-particle flows over a backward-facing step geometry are investigated. An investigation is performed to assess the performance of two computational...
Thermal-hydrodynamic modeling of bubbly flows with heat and mass transfer (2005)
A three-dimensional (3-D) two-fluid model coupled with the population balance equation is used to predict bubbly flows with the presence of heat and mass transfer processes, particularly on subcooled...
Population balance equations combined with a three-dimensional two-fluid model are employed to predict subcooled boiling flow at low pressure in a vertical annular channel. The MUltiple-SIze-Group...
A bubble mechanistic model for subcooled boiling flow predictions (2004)
Population balance equations combined with a three-dimensional two-fluid model are employed to predict subcooled boiling flow at low pressure in a vertical annular channel. The MUSIG...
Morsi, Y, Tu, J, Yeoh, G, Yang, W
In this paper the particle rebounding characteristics of a gas-particle flow over a cylindrical body and an in-line tube bundle arrangement is investigated. With the aid of both experimental and...
A three-dimensional two-fluid model to predict subcooled boiling flow at low pressure is presented. The model is adopted to investigate the two-phase flow and heat transfer characteristics in a...
On void fraction distribution during two-phase boiling flow instability (2004)
[article extract] Flow instability is an important consideration in the design of nuclear reactors because of the possible occurrence of flow excursion during a postulated accident. The present...
Population balance modelling for bubbly flows with heat and mass transfer (2004)
Population balance equations combined with a three-dimensional two-fluid model are employed to predict bubbly flows with the presence of heat and mass transfer processes. Subcooled boiling flow...
Assessment of two-equation turbulence modelling for high Reynolds number hydrofoil flows (2004)
Mulvany, N, Tu, J, Chen, L, Anderson, B
This paper presents an evaluation of the capability of turbulence models available in the commercial CFD code FLUENT 6.0 for their application to hydrofoil turbulent boundary layer separation flow at...
Fluid flow in an animal model of post-traumatic syringomyelia (2003)
Brodbelt, A. R., Stoodley, M. A., Watling, A. M., Tu, J., Jones, N. R.
The role of excitotoxic injury in post-traumatic syringomyelia (2003)
Brodbelt, A. R., Stoodley, M. A., Watling, A. M., Rogan, C., Tu, J., Brown, C. J., ...
Fluid flow in an animal model of post-traumatic syringomyelia (2003)
Brodbelt, A. R., Stoodley, M. A., Watling, A. M., Tu, J., Jones, N. R.
The role of excitotoxic injury in post-traumatic syringomyelia (2003)
Brodbelt, A. R., Stoodley, M. A., Watling, A. M., Rogan, C., Tu, J., Brown, C. J., ...
Tu, J, Shan, QX, Jin, HF, Bruce, IC, Xia, Q
In the present study, we used the Langendorff technique to evaluate the involvement of endothelin-1 (ET-I) and nitric oxide (NO) in coronary vasoconstriction and myocardial depression in hearts...
Vasorelaxant effect of total flavones from Dendranthema morifolium on rat thoracic aorta (2003)
Jin, HF, Shan, QX, Jiang, HD, Tu, J, Bruce, IC, Xia, Q
To investigate the vasorelaxant effect of total flavones from Dendranthema morifolium (Ramat.) Tzvel. cv. Hangju (FDM), tension was recorded from rat thoracic aortic rings. FDM completely relaxed, in...
Numerical investigation of flow instability in a low-pressure subcooled boiling channel (2003)
A three-dimensional two-fluid model to predict subcooled boiling flow at low pressure is presented. The model is adopted to investigate the two-phase flow and heat transfer characteristics in a...
A large-eddy simulation of two side-by-side circular cylinders in cross flow (2003)
Large eddy simulation cooperated with the second order full extension ETG (Euler-Taylor-Galerkin) finite element method was applied to simulate the flow around two square cylinders arranged side by...
A three-dimensional two-fluid model to predict subcooled boiling flow at low pressure is presented. The model is adopted to investigate the two-phase flow and heat transfer characteristics in a...
Numerical simulation of turbulent wake flows behind two side-by-side cylinders (2003)
The formation and the convection of vortices behind two side-by-side cylinders are investigated using the large-eddy simulation (LES) model. Solution to the three-dimensional Navier-Stokes governing...
A Framework, Validation Computer, J. O. Berger, D. Higdon, M. C. Kennedy, ...
Abstract In this paper, we present a framework that enables computer model evaluation oriented towards answering the question: Does the computer model adequately represent reality? The proposed...
A framework for validation of computer models (2002)
M. J. Bayarri, J. O. Berger, D. Higdon, M. C. Kennedy, A. Kottas, R. Paulo, ...
In this paper, we present a framework that enables computer model evaluation oriented towards answering the question: Does the computer model adequately represent reality? The proposed validation...
Radiologic investigations and pathologic results of experimental chronic pancreatitis in cats (1999)
Tu, J, Martens, A, Oord, J V, ...
RATIONALE AND OBJECTIVES: The purpose of this study was to evaluate a variety of methods to induce chronic pancreatitis and its radiologic expression by experimentally inducing this condition in...
Radiologic investigations and pathologic results of experimental chronic pancreatitis in cats (1999)
Tu, J, Martens, A, Oord, JV, ...
RATIONALE AND OBJECTIVES: The purpose of this study was to evaluate a variety of methods to induce chronic pancreatitis and its radiologic expression by experimentally inducing this condition in...
BACKGROUND/AIMS: Obstruction of the main pancreatic duct leads to progressive obstructive and atrophying pancreatitis in the cat. The question remains whether "early" derivative procedures can halt...
BACKGROUND: The pathogenesis of chronic pancreatitis remains unclear. This investigation aimed to evaluate the relative importance of acinar or ductal lesions or of ductal subobstruction in the...
Inhibition of HIV type 1 Tat-mediated trans-activation by oncostatin M in HLtat cells (1995)
We have tested the effect of oncostatin M (OSM) on the Tat-mediated trans-activation in a HeLa cell line (HLtat) expressing Tat, using a transfection assay with the LacZ gene under the control of the...
BACKGROUND—Ipratropium is commonly used for the management of elderly patients with obstructive airway disease. However, a recent report suggested that its use might be associated with a...
A component-based, distributed object services architecture for a clinical workstation.
Chueh, H. C., Raila, W. F., Pappas, J. J., Ford, M., Zatsman, P., Tu, J., ...
Attention to an architectural framework in the development of clinical applications can promote reusability of both legacy systems as well as newly designed software. We describe one approach to an...