J. Turgeon

Publication List Details

Period

1988 - 1990

Number

10

Co-Authors

Nature of the clinical difficulties of first-year family medicine residents under direct observation.

Beaumier, A, Bordage, G, Saucier, D, Turgeon, J

OBJECTIVE: To determine and classify the difficulties of first-year family medicine residents observed during clinical interviews. DESIGN: Retrospective, descriptive study. SETTING: Family practice...

Nature of the clinical difficulties of first-year family medicine residents under direct observation.

Beaumier, A, Bordage, G, Saucier, D, Turgeon, J

OBJECTIVE: To determine and classify the difficulties of first-year family medicine residents observed during clinical interviews. DESIGN: Retrospective, descriptive study. SETTING: Family practice...

Stereoselective disposition of (+/-)-sotalol at steady-state conditions.

Fiset, C, Philippon, F, Gilbert, M, Turgeon, J

The objective of this study was to assess, under steady-state conditions, the stereoselective disposition of (+/-)-sotalol in man. In all patients studied (n = 7) values of oral clearance (137 +/- 51...

Phenotypic debrisoquine 4-hydroxylase activity among extensive metabolizers is unrelated to genotype as determined by the Xba-I restriction fragment length polymorphism.

Turgeon, J, Evans, W E, Relling, M V, Wilkinson, G R, Roden, D M

1. The major pathway for 4-hydroxylation of debrisoquine in man is polymorphic and under genetic control. More than 90% of subjects (extensive metabolizers, EMs) have active debrisoquine...

Stereoselective genetically-determined interaction between chronic flecainide and quinidine in patients with arrhythmias.

Birgersdotter, U M, Wong, W, Turgeon, J, Roden, D M

1. Recent reports have indicated a role for the P450IID6 polymorphism in the stereoselective disposition of single doses of the antiarrhythmic flecainide. 2. In this study, we evaluated the effects...

Stereoselective disposition of mexiletine in man.

Grech-Belanger, O, Turgeon, J, Gilbert, M

The pharmacokinetics of S-(+)- and R-(-)-mexiletine and of the corresponding conjugates were investigated in six healthy young volunteers after administration of a single 200 mg oral dose of racemic...

Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurised metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode

Drblik, S, Lapierre, G, Thivierge, R, Turgeon, J, Gaudreault, P, Cummins-McManus, B, ...

Aims: To compare the efficacy of terbutaline sulphate delivered via Turbuhaler with a pressurised metered dose inhaler (pMDI) connected to Nebuhaler spacer in a population of asthmatic children...