Orrú, Valeria, Tsai, Sophia J., Rueda, Blanca, Fiorillo, Edoardo, Stanford, Stephanie M., Dasgupta, Jhimli, ...
A gain-of-function R620W polymorphism in the PTPN22 gene, encoding the lymphoid tyrosine phosphatase LYP, has recently emerged as an important risk factor for human autoimmunity. Here we report that...
Functional analysis of 5-lipoxygenase promoter repeat variants (2009)
Vikman, Susanna, Brena, Romulo M., Armstrong, Patrice, Hartiala, Jaana, Stephensen, Charles B., Allayee, Hooman
Variants of a hexanucleotide repeat polymorphism in the promoter of the 5-lipoxygenase (5-LO) gene have been associated with cardiovascular disease traits in humans, which may be due, at least in...
A Susceptibility Locus for Migraine with Aura, on Chromosome 4q24
Wessman, Maija, Kallela, Mikko, Kaunisto, Mari A., Marttila, Pia, Sobel, Eric, Hartiala, Jaana, ...
Migraine is a complex neurovascular disorder with substantial evidence supporting a genetic contribution. Prior attempts to localize susceptibility loci for common forms of migraine have not produced...