Antibiotic guidelines and antibiotic use in adult bacterial meningitis in The Netherlands (2002)
Van De Beek, Diederik, De Gans, Jan, Spanjaard, Lodewijk, Vermeulen, Marinus, Dankert, Jacob
In The Netherlands, national guidelines for the treatment of adult patients with bacterial meningitis were introduced in October 1997. In 1998 we began a prospective, nationwide study to evaluate the...
Kuijpers, Alma J., Ehlert, Jan E., Brandt, Ernst, Poolman, Bert, Fang, Gang, Veelen, Peter A. Van, ...
Antibacterial proteins are components of the innate immune system found in many organisms and produced by a variety of cell types. Human blood platelets contain a number of antibacterial proteins in...
Vriesema, Aldwin J.M., Brinkman, René, Kok, Jan, Dankert, Jacob, Zaat, Sebastian A.J.
Viridans group streptococci are major constituents of the normal human oral flora and are also identified as the predominant pathogenic bacteria in native valve infective endocarditis. Little...
Krijgsveld, Jeroen, Zaat, Sebastian A.J., Meeldijk, Jan, Veelen, Peter A. Van, Fang, Gang, Poolman, Bert, ...
Antibacterial proteins are components of the innate immune system found in many organisms and produced by a variety of cell types. Human blood platelets contain a number of antibacterial proteins in...
Boelens, Jaap J., Tan, Wee-Fu, Dankert, Jacob, Zaat, Sebastian A. J.
If shunts, inserted for the relief of hydrocephalus, are pretreated with antimicrobials, the incidence of shunt-associated infections (SAI) may be reduced. The duration of the antibacterial activity...
In the pathogenesis of infective endocarditis the adherence of circulating bacteria to a preexisting cardiac vegetation (VG) and the survival of bacteria adherent to VG's are major events. One...
Van Dam, Alje P., Van Gool, Tom, Dankert, Jacob
West African tick-borne relapsing fever (TBRF) is difficult to diagnose due to the low number of spirochetes in the bloodstream of patients. Previously, the causative microorganism, Borrelia...
Wang, Guiqing, Van Dam, Alje P., Dankert, Jacob
Borrelia burgdorferi sensu lato A14S was cultured from a skin biopsy specimen of a patient with erythema migrans in The Netherlands. This isolate had a unique DNA fingerprint pattern compared to 135...
Dorigo-Zetsma, J. Wendelien, Dankert, Jacob, Zaat, Sebastian A. J.
Three methods for genotyping of Mycoplasma pneumoniae clinical isolates were applied to 2 reference strains and 21 clinical isolates. By a modified restriction fragment length polymorphism (RFLP)...
Wever, Peter C., Yzerman, Ed P. F., Kuijper, Ed J., Speelman, Peter, Dankert, Jacob
A new immunochromatographic assay for rapid qualitative detection of Legionella pneumophila serogroup 1 antigen in urine specimens was used during an outbreak of legionellosis in The Netherlands. The...
Pannekoek, Yvonne, Westenberg, Steven M., De Vries, Jan, Repping, Sjoerd, Spanjaard, Lodewijk, Eijk, Paul P., ...
In order to ascertain the microbiological quality of stored semen specimens processed for artificial insemination by a donor (AID), we developed a PCR assay targeting the chlamydial plasmid to detect...
Genetic Relatedness within Serotypes of Penicillin-Susceptible Streptococcus pneumoniae Isolates
Overweg, Karin, Bogaert, Debby, Sluijter, Marcel, Yother, Janet, Dankert, Jacob, De Groot, Ronald, ...
The molecular epidemiological characteristics of all Streptococcus pneumoniae strains isolated in a nationwide manner from patients with meningitis in The Netherlands in 1994 were investigated....
Apparent Culture-Negative Prosthetic Valve Endocarditis Caused by Peptostreptococcus magnus
Van Der Vorm, Eric R., Dondorp, Arjen M., Van Ketel, Ruud J., Dankert, Jacob
In two patients with prosthetic valve endocarditis due to Peptostreptococcus magnus, blood cultures in the BacT/Alert and BACTEC 9240 systems were signal negative. The capability of the BacT/Alert...
Wang, Guiqing, Van Dam, Alje P., Schwartz, Ira, Dankert, Jacob
Borrelia burgdorferi sensu lato, the spirochete that causes human Lyme borreliosis (LB), is a genetically and phenotypically divergent species. In the past several years, various molecular approaches...
Regelink, Annette G., Dahan, David, Möller, Lieke V. M., Coulton, James W., Eijk, Paul, Van Ulsen, Peter, ...
We investigated the relationship between susceptibility to β-lactam antibiotics and variation in the major outer membrane protein P2 (OmpP2; also called porin) of persistent nonencapsulated...
Vriesema, Aldwin J. M., Brinkman, René, Kok, Jan, Dankert, Jacob, Zaat, Sebastian A. J.
Viridans group streptococci are major constituents of the normal human oral flora and are also identified as the predominant pathogenic bacteria in native valve infective endocarditis. Little...
Bart, Aldert, Dankert, Jacob, Van Der Ende, Arie
Since 1980, the number of cases of meningococcal disease caused by serogroup B isolates with the P1.4 serosubtype has greatly increased in The Netherlands. Screening for this serosubtype in the...
cagA-Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct
Van Der Ende, Arie, Pan, Zhi-Jun, Bart, Aldert, Feller, Monique, Xiao, Shu-dong, ...
Vriesema, Aldwin J. M., Dankert, Jacob, Zaat, Sebastian A. J.
Viridans group streptococci (VS) from the oral cavity entering the bloodstream may initiate infective endocarditis (IE). We aimed to identify genes expressed in response to a pH increase from...
Altered Gene Expression in Staphylococcus aureus upon Interaction with Human Endothelial Cells
Vriesema, Aldwin J. M., Beekhuizen, Henry, Hamdi, Mohamed, Soufan, Alexandre, Lammers, Aart, Willekens, Ben, ...
Staphylococcus aureus is isolated from a substantial number of patients with infective endocarditis who are not known to have predisposing heart abnormalities. It has been suggested that the...
Multiple Mechanisms of Phase Variation of PorA in Neisseria meningitidis
Van Der Ende, Arie, Hopman, Carla T. P., Dankert, Jacob
Previously, we reported that PorA expression in Neisseria meningitidis is modulated by variation in the length of the homopolymeric tract of guanidine residues between the −35 and −10 regions of...
Boelens, Jaap Jan, Van Der Poll, Tom, Zaat, Sebastian A. J., Weening, Jan J., Dankert, Jacob
Elevated concentrations of interleukin-1 (IL-1) were found in tissue surrounding biomaterials infected with Staphylococcus epidermidis. To determine the role of IL-1 in biomaterial-associated...
Bart, Aldert, Pannekoek, Yvonne, Dankert, Jacob, Van Der Ende, Arie
Neisseria meningitidis is a gram-negative bacterium that may cause meningitis, sepsis, or both. The increase in the incidence of meningococcal disease in various countries in the past 2 decades is...
Van Schilfgaarde, Muriel, Van Ulsen, Peter, Van Der Steeg, Wim, Winter, Victor, Eijk, Paul, Everts, Vincent, ...
Haemophilus influenzae penetrates between epithelial cells via an unknown mechanism. A chromosomal library of nonencapsulated H. influenzae strain A960053 DNA was constructed in Escherichia coli...
Characterization of Adherence of Nontypeable Haemophilus influenzae to Human Epithelial Cells
Van Schilfgaarde, Muriel, Van Ulsen, Peter, Eijk, Paul, Brand, Michiel, Stam, Martin, Kouame, Jamal, ...
The adherence of 58 nontypeable Haemophilus influenzae isolates obtained from patients with otitis media or chronic obstructive pulmonary disease (COPD) and obtained from the throats of healthy...
Pannekoek, Yvonne, Van Der Ende, Arie, Eijk, Paul P., Van Marle, Jan, De Witte, Moniek A., Ossewaarde, Jacobus M., ...
To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were...
Dorigo-Zetsma, J. Wendelien, Wilbrink, Berry, Dankert, Jacob, Zaat, Sebastian A. J.
Mycoplasma pneumoniae strains traditionally are divided into two types, based on sequence variation in the P1 gene. Recently, however, we have identified 8 P1 subtypes by restriction fragment length...
Wang, Guiqing, Van Dam, Alje P., Spanjaard, Lodewijk, Dankert, Jacob
To study whether pathogenic clusters of Borrelia burgdorferi sensu lato strains occur, we typed 136 isolates, cultured from specimens from patients (n = 49) with various clinical entities and from...
Bart, Aldert, Schuurman, Ilse G. A., Achtman, Mark, Caugant, Dominique A., Dankert, Jacob, Van Der Ende, Arie
Randomly amplified polymorphic DNA (RAPD) genotyping was applied to one representative strain of each of the 84 electrophoretic types (ETs) of Neisseria meningitidis serogroup A previously defined by...
Möller, Lieke V. M., Regelink, Annette G., Grasselier, Henny, Van Alphen, Loek, Dankert, Jacob
We analyzed the antimicrobial susceptibilities of Haemophilus influenzae isolates from 157 sputum specimens prospectively collected from 39 cystic fibrosis (CF) patients during a 2-year study. These...
cagA-Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct
Van Der Ende, Arie, Pan, Zhi-Jun, Bart, Aldert, Feller, Monique, Xiao, Shu-Dong, ...
The aim of this research was to study whether and to what extent Chinese cagA-positive Helicobacter pylori isolates differ from those in The Netherlands. Analysis of random amplified polymorphic DNA...
Pan, Zhi-Jun, Su, Wan-Wen, Tytgat, Guido N. J., Dankert, Jacob, Van Der Ende, Arie
Of 96 Helicobacter pylori isolates from patients in Shanghai and Guangzhou, China, 5 had the A2143G 23S rRNA mutation as determined by primer-mismatch PCR and were resistant to clarithromycin by the...
Yzerman, Ed P. F., Boer, Jeroen W. Den, Lettinga, Kamilla D., Schellekens, Joop, Dankert, Jacob, Peeters, Marcel
In 1999 an outbreak involving 188 patients with Legionnaires' disease (LD) occurred among visitors to a flower show in the Netherlands. Two enzyme immunoassays (Binax and Biotest) and one...
Detection of Imported Malaria with the Cell-Dyn 4000 Hematology Analyzer
Wever, Peter C., Henskens, Yvonne M. C., Kager, Piet A., Dankert, Jacob, Van Gool, Tom
The sensitivity and specificity of the Cell-Dyn 4000 hematology analyzer in the diagnosis of imported malaria were studied with samples from patients in an academic hospital setting. The performance...
Van Doorn, H. Rogier, Claas, Eric C. J., Templeton, Kate E., Te Koppele Vije, Arianne, De Jong, Menno D., ...
Tuberculosis remains one of the leading infectious causes of death worldwide. The emergence of drug-resistant strains of Mycobacterium tuberculosis is a serious public health threat. Resistance to...
Ringrose, Jeffrey H., Meiring, Hugo D., Speijer, Dave, Feltkamp, Theodorus E. W., ...
Reactive arthritis (ReA) induced by infection with several gram-negative bacteria is strongly associated with expression of the major histocompatibility complex class I molecule HLA-B27. It is...
Dankert, Jacob, Van Der Werff, Janneke, Joldersma, Willem, Zaat, Sebastian A. J.
Major predisposing conditions for infective endocarditis (IE) are the presence of a cardiac platelet-fibrin vegetation and of circulating bacteria with relatively low susceptibility to microbicidal...
Van Dam, Alje P., Van Gool, Tom, Dankert, Jacob
West African tick-borne relapsing fever (TBRF) is difficult to diagnose due to the low number of spirochetes in the bloodstream of patients. Previously, the causative microorganism, Borrelia...
Wang, Guiqing, Van Dam, Alje P., Dankert, Jacob
Borrelia burgdorferi sensu lato A14S was cultured from a skin biopsy specimen of a patient with erythema migrans in The Netherlands. This isolate had a unique DNA fingerprint pattern compared to 135...
Dorigo-Zetsma, J. Wendelien, Dankert, Jacob, Zaat, Sebastian A. J.
Three methods for genotyping of Mycoplasma pneumoniae clinical isolates were applied to 2 reference strains and 21 clinical isolates. By a modified restriction fragment length polymorphism (RFLP)...
Wever, Peter C., Yzerman, Ed P. F., Kuijper, Ed J., Speelman, Peter, Dankert, Jacob
A new immunochromatographic assay for rapid qualitative detection of Legionella pneumophila serogroup 1 antigen in urine specimens was used during an outbreak of legionellosis in The Netherlands. The...
Pannekoek, Yvonne, Westenberg, Steven M., De Vries, Jan, Repping, Sjoerd, Spanjaard, Lodewijk, Eijk, Paul P., ...
In order to ascertain the microbiological quality of stored semen specimens processed for artificial insemination by a donor (AID), we developed a PCR assay targeting the chlamydial plasmid to detect...
Genetic Relatedness within Serotypes of Penicillin-Susceptible Streptococcus pneumoniae Isolates
Overweg, Karin, Bogaert, Debby, Sluijter, Marcel, Yother, Janet, Dankert, Jacob, De Groot, Ronald, ...
The molecular epidemiological characteristics of all Streptococcus pneumoniae strains isolated in a nationwide manner from patients with meningitis in The Netherlands in 1994 were investigated....
Apparent Culture-Negative Prosthetic Valve Endocarditis Caused by Peptostreptococcus magnus
Van Der Vorm, Eric R., Dondorp, Arjen M., Van Ketel, Ruud J., Dankert, Jacob
In two patients with prosthetic valve endocarditis due to Peptostreptococcus magnus, blood cultures in the BacT/Alert and BACTEC 9240 systems were signal negative. The capability of the BacT/Alert...
Wang, Guiqing, Van Dam, Alje P., Schwartz, Ira, Dankert, Jacob
Borrelia burgdorferi sensu lato, the spirochete that causes human Lyme borreliosis (LB), is a genetically and phenotypically divergent species. In the past several years, various molecular approaches...
Regelink, Annette G., Dahan, David, Möller, Lieke V. M., Coulton, James W., Eijk, Paul, Van Ulsen, Peter, ...
We investigated the relationship between susceptibility to β-lactam antibiotics and variation in the major outer membrane protein P2 (OmpP2; also called porin) of persistent nonencapsulated...
Vriesema, Aldwin J. M., Brinkman, René, Kok, Jan, Dankert, Jacob, Zaat, Sebastian A. J.
Viridans group streptococci are major constituents of the normal human oral flora and are also identified as the predominant pathogenic bacteria in native valve infective endocarditis. Little...
Bart, Aldert, Dankert, Jacob, Van Der Ende, Arie
Since 1980, the number of cases of meningococcal disease caused by serogroup B isolates with the P1.4 serosubtype has greatly increased in The Netherlands. Screening for this serosubtype in the...
cagA-Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct
Van Der Ende, Arie, Pan, Zhi-Jun, Bart, Aldert, Feller, Monique, Xiao, Shu-dong, ...
Vriesema, Aldwin J. M., Dankert, Jacob, Zaat, Sebastian A. J.
Viridans group streptococci (VS) from the oral cavity entering the bloodstream may initiate infective endocarditis (IE). We aimed to identify genes expressed in response to a pH increase from...
Altered Gene Expression in Staphylococcus aureus upon Interaction with Human Endothelial Cells
Vriesema, Aldwin J. M., Beekhuizen, Henry, Hamdi, Mohamed, Soufan, Alexandre, Lammers, Aart, Willekens, Ben, ...
Staphylococcus aureus is isolated from a substantial number of patients with infective endocarditis who are not known to have predisposing heart abnormalities. It has been suggested that the...
Multiple Mechanisms of Phase Variation of PorA in Neisseria meningitidis
Van Der Ende, Arie, Hopman, Carla T. P., Dankert, Jacob
Previously, we reported that PorA expression in Neisseria meningitidis is modulated by variation in the length of the homopolymeric tract of guanidine residues between the −35 and −10 regions of...
Boelens, Jaap Jan, Van Der Poll, Tom, Zaat, Sebastian A. J., Weening, Jan J., Dankert, Jacob
Elevated concentrations of interleukin-1 (IL-1) were found in tissue surrounding biomaterials infected with Staphylococcus epidermidis. To determine the role of IL-1 in biomaterial-associated...
Bart, Aldert, Pannekoek, Yvonne, Dankert, Jacob, Van Der Ende, Arie
Neisseria meningitidis is a gram-negative bacterium that may cause meningitis, sepsis, or both. The increase in the incidence of meningococcal disease in various countries in the past 2 decades is...
Van Schilfgaarde, Muriel, Van Ulsen, Peter, Van Der Steeg, Wim, Winter, Victor, Eijk, Paul, Everts, Vincent, ...
Haemophilus influenzae penetrates between epithelial cells via an unknown mechanism. A chromosomal library of nonencapsulated H. influenzae strain A960053 DNA was constructed in Escherichia coli...
Characterization of Adherence of Nontypeable Haemophilus influenzae to Human Epithelial Cells
Van Schilfgaarde, Muriel, Van Ulsen, Peter, Eijk, Paul, Brand, Michiel, Stam, Martin, Kouame, Jamal, ...
The adherence of 58 nontypeable Haemophilus influenzae isolates obtained from patients with otitis media or chronic obstructive pulmonary disease (COPD) and obtained from the throats of healthy...
Pannekoek, Yvonne, Van Der Ende, Arie, Eijk, Paul P., Van Marle, Jan, De Witte, Moniek A., Ossewaarde, Jacobus M., ...
To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were...
Dorigo-Zetsma, J. Wendelien, Wilbrink, Berry, Dankert, Jacob, Zaat, Sebastian A. J.
Mycoplasma pneumoniae strains traditionally are divided into two types, based on sequence variation in the P1 gene. Recently, however, we have identified 8 P1 subtypes by restriction fragment length...
Wang, Guiqing, Van Dam, Alje P., Spanjaard, Lodewijk, Dankert, Jacob
To study whether pathogenic clusters of Borrelia burgdorferi sensu lato strains occur, we typed 136 isolates, cultured from specimens from patients (n = 49) with various clinical entities and from...
Bart, Aldert, Schuurman, Ilse G. A., Achtman, Mark, Caugant, Dominique A., Dankert, Jacob, Van Der Ende, Arie
Randomly amplified polymorphic DNA (RAPD) genotyping was applied to one representative strain of each of the 84 electrophoretic types (ETs) of Neisseria meningitidis serogroup A previously defined by...
Möller, Lieke V. M., Regelink, Annette G., Grasselier, Henny, Van Alphen, Loek, Dankert, Jacob
We analyzed the antimicrobial susceptibilities of Haemophilus influenzae isolates from 157 sputum specimens prospectively collected from 39 cystic fibrosis (CF) patients during a 2-year study. These...
cagA-Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct
Van Der Ende, Arie, Pan, Zhi-Jun, Bart, Aldert, Feller, Monique, Xiao, Shu-Dong, ...
The aim of this research was to study whether and to what extent Chinese cagA-positive Helicobacter pylori isolates differ from those in The Netherlands. Analysis of random amplified polymorphic DNA...
Pan, Zhi-Jun, Su, Wan-Wen, Tytgat, Guido N. J., Dankert, Jacob, Van Der Ende, Arie
Of 96 Helicobacter pylori isolates from patients in Shanghai and Guangzhou, China, 5 had the A2143G 23S rRNA mutation as determined by primer-mismatch PCR and were resistant to clarithromycin by the...
Yzerman, Ed P. F., Boer, Jeroen W. Den, Lettinga, Kamilla D., Schellekens, Joop, Dankert, Jacob, Peeters, Marcel
In 1999 an outbreak involving 188 patients with Legionnaires' disease (LD) occurred among visitors to a flower show in the Netherlands. Two enzyme immunoassays (Binax and Biotest) and one...
Detection of Imported Malaria with the Cell-Dyn 4000 Hematology Analyzer
Wever, Peter C., Henskens, Yvonne M. C., Kager, Piet A., Dankert, Jacob, Van Gool, Tom
The sensitivity and specificity of the Cell-Dyn 4000 hematology analyzer in the diagnosis of imported malaria were studied with samples from patients in an academic hospital setting. The performance...
Van Doorn, H. Rogier, Claas, Eric C. J., Templeton, Kate E., Te Koppele Vije, Arianne, De Jong, Menno D., ...
Tuberculosis remains one of the leading infectious causes of death worldwide. The emergence of drug-resistant strains of Mycobacterium tuberculosis is a serious public health threat. Resistance to...
Ringrose, Jeffrey H., Meiring, Hugo D., Speijer, Dave, Feltkamp, Theodorus E. W., ...
Reactive arthritis (ReA) induced by infection with several gram-negative bacteria is strongly associated with expression of the major histocompatibility complex class I molecule HLA-B27. It is...
Dankert, Jacob, Van Der Werff, Janneke, Joldersma, Willem, Zaat, Sebastian A. J.
Major predisposing conditions for infective endocarditis (IE) are the presence of a cardiac platelet-fibrin vegetation and of circulating bacteria with relatively low susceptibility to microbicidal...
Broekhuizen, Corine A. N., De Boer, Leonie, Schipper, Kim, Jones, Christopher D., Quadir, Shan, Feldman, Roger G., ...
Biomaterial-associated infections (BAI), which are predominantly caused by Staphylococcus epidermidis, are a significant problem in modern medicine. Biofilm formation is considered the pivotal...