Jacobijn Gussekloo

Clinical relevance of a raised plasma N-terminal pro-brain natriuretic peptide level in a population-based cohort of nonagenarians (2009)

De Ruijter, Wouter, Westendorp, Rudi G J, Gussekloo, Jacobijn

OBJECTIVES: To investigate whether plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) remains a specific marker of cardiac illness in very old age and can be used to identify very elderly...

The accuracy of plasma natriuretic peptide levels for diagnosis of cardiac dysfunction and chronic heart failure in community-dwelling elderly: a systematic review (2009)

Vaes, Bert, De Ruijter, Wouter, Gussekloo, Jacobijn, Degryse, Jan

Background: measurement of plasma natriuretic peptide levels has been proposed as a simple, accessible test to assist the diagnosis of cardiac dysfunction and heart failure. Most studies have been...

Randomised Controlled Trial of Unsolicited Occupational Therapy in Community-Dwelling Elderly People: The LOTIS Trial (2006)

Jacobijn Gussekloo, Gerard J. Blauw, Charles G. Willems

Objective:The objective of this trial, the Leiden 85-Plus Occupational Therapy Intervention Study (LOTIS), was to assess whether unsolicited occupational therapy, as compared to no therapy, can...

Meta-Analysis of Nonsteroidal Antiinflammatory Drug Use and Risk of Dementia (2005)

Gussekloo, Jacobijn, Vrijsen, Bram, Westendorp, Rudi G. J.

The authors performed a systematic review to summarize the epidemiologic evidence on the association between use of nonsteroidal antiinflammatory drugs (NSAIDs) and the risk of dementia. A total of...

Association between chronic diseases and disability in elderly subjects with low and high income: the Leiden 85-plus Study (2005)

Van Exel, Eric, Macfarlane, Peter W., Gussekloo, Jacobijn, Westendorp, Rudi G.J.

Background: Disability in activities of daily living (ADL) might be more prevalent among elderly with low income due to higher prevalence of chronic diseases and impairments, as well as stronger...

Auditory rehabilitation of older people from the general population--the Leiden 85-plus study.

Gussekloo, Jacobijn, De Bont, L E, Von Faber, M, Eekhof, J A, De Laat, J A, Hulshof, J H, ...

BACKGROUND: Very few older people with severe hearing loss use hearing aids to reduce the negative consequences of reduced hearing in daily functioning. AIM: Assessment of a screening test and a...

Auditory rehabilitation of older people from the general population--the Leiden 85-plus study.

Gussekloo, Jacobijn, De Bont, L E, Von Faber, M, Eekhof, J A, De Laat, J A, Hulshof, J H, ...

BACKGROUND: Very few older people with severe hearing loss use hearing aids to reduce the negative consequences of reduced hearing in daily functioning. AIM: Assessment of a screening test and a...

Use of Framingham risk score and new biomarkers to predict cardiovascular mortality in older people: population based observational cohort study

De Ruijter, Wouter, Westendorp, Rudi G J, Assendelft, Willem J J, Le Cessie, Saskia, ...

Objectives To investigate the performance of classic risk factors, and of some new biomarkers, in predicting cardiovascular mortality in very old people from the general population with no history of...