Jacqueline M. Agans

Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs

Foster, Carolyn J., Prosser, Dina M., Agans, Jacqueline M., Zhai, Ying, Smith, Michelle D., Lachowicz, Jean E., ...

ADP plays a critical role in modulating thrombosis and hemostasis. ADP initiates platelet aggregation by simultaneous activation of two G protein–coupled receptors, P2Y1 and P2Y12. Activation of...

Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs

Foster, Carolyn J., Prosser, Dina M., Agans, Jacqueline M., Zhai, Ying, Smith, Michelle D., Lachowicz, Jean E., ...

ADP plays a critical role in modulating thrombosis and hemostasis. ADP initiates platelet aggregation by simultaneous activation of two G protein–coupled receptors, P2Y1 and P2Y12. Activation of...