The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation (2009)
Boukarabila, Hanane, Saurin, Andrew J., Batsché, Eric, Mossadegh, Noushine, Van Lohuizen, Maarten, Otte, Arie P., ...
Ectopic repression of retinoic acid (RA) receptor target genes by PML/RARA and PLZF/RARA fusion proteins through aberrant recruitment of nuclear corepressor complexes drives cellular transformation...
Miotto, Benoit, Sagnier, Thierry, Berenger, Hélène, Bohmann, Dirk, Pradel, Jacques, Graba, Yacine
Gene regulation by AP-1 transcription factors in response to Jun N-terminal kinase (JNK) signaling controls essential cellular processes during development and in pathological situations. Here, we...
Krejci, Eric, Garzino, Veronique, Mary, Charles, Bennani, Naima, Pradel, Jacques
We have cloned, following an immunological screen of an expression library, five cDNA clones encoding the modulo antigen, a DNA-binding protein differentially expressed during Drosophila development....
A propos de trois cas de protusion acétabulaire / (1954)
Thèse de Médecine : Université de Lyon : Faculté de Médecine et de Pharmacie.
Distinct Hox protein sequences determine specificity in different tissues
Chauvet, Sophie, Merabet, Samir, Bilder, David, Scott, Matthew P., Pradel, Jacques, Graba, Yacine
Hox genes encode evolutionarily conserved transcription factors that control the morphological diversification along the anteroposterior (A/P) body axis. Expressed in precise locations in the...
Pontin52 and Reptin52 function as antagonistic regulators of β-catenin signalling activity
Bauer, Andreas, Chauvet, Sophie, Huber, Otmar, Usseglio, Fabrice, Rothbächer, Ute, Aragnol, Denise, ...
In Wnt-stimulated cells, β-catenin becomes stabilized in the cytoplasm, enters the nucleus and interacts with HMG box transcription factors of the lymphoid-enhancing factor-1 (LEF-1)/T-cell factor...
Bellosta, Paola, Hulf, Toby, Diop, Soda Balla, Usseglio, Fabrice, Pradel, Jacques, Aragnol, Denise, ...
The transcription factor dMyc is the sole Drosophila ortholog of the vertebrate c-myc protooncogenes and a central regulator of growth and cell-cycle progression during normal development. We have...
Miotto, Benoit, Sagnier, Thierry, Berenger, Hélène, Bohmann, Dirk, Pradel, Jacques, Graba, Yacine
Gene regulation by AP-1 transcription factors in response to Jun N-terminal kinase (JNK) signaling controls essential cellular processes during development and in pathological situations. Here, we...
Merabet, Samir, Catala, Francoise, Pradel, Jacques, Graba, Yacine
Hox genes encode evolutionarily conserved transcription factors that play fundamental roles in the organization of the animal body plan. Molecular studies emphasize that unidentified genes contribute...
A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax
Merabet, Samir, Saadaoui, Mehdi, Sambrani, Nagraj, Hudry, Bruno, Pradel, Jacques, Affolter, Markus, ...
Hox transcription factors are essential for shaping body morphology in development and evolution. The control of Hox protein activity in part arises from interaction with the PBC class of partners,...
Reptin and Pontin function antagonistically with PcG and TrxG complexes to mediate Hox gene control
Diop, Soda Balla, Bertaux, Karine, Vasanthi, Dasari, Sarkeshik, Ali, Goirand, Benjamin, Aragnol, Denise, ...
Pontin (Pont) and Reptin (Rept) are paralogous ATPases that are evolutionarily conserved from yeast to human. They are recruited in multiprotein complexes that function in various aspects of DNA...
The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation
Boukarabila, Hanane, Saurin, Andrew J., Batsché, Eric, Mossadegh, Noushine, Van Lohuizen, Maarten, Otte, Arie P., ...
Ectopic repression of retinoic acid (RA) receptor target genes by PML/RARA and PLZF/RARA fusion proteins through aberrant recruitment of nuclear corepressor complexes drives cellular transformation...