Jakob Hedegaard

Methods for interpreting lists of affected genes obtained in a DNA microarray experiment (2009)

Hedegaard, Jakob, Arce, Cristina, Bicciato, Silvio, Bonnet, Agnès, Buitenhuis, Bart, Collado-Romero, Melania, ...

Abstract Background The aim of this paper was to describe and compare the methods used and the results obtained by the participants in a joint EADGENE (European Animal Disease Genomic Network of...

Gene set analysis methods applied to chicken microarray expression data (2009)

Skarman, Axel, Jiang, Li, Henrik, Hornshøj, Buitenhuis, Bart, Hedegaard, Jakob, Conley, Lene N, ...

Abstract Background Gene set analysis is considered to be a way of improving our biological interpretation of the observed expression patterns. This paper describes different methods applied to...

Transcriptomic and proteomic profiling of two porcine tissues using high-throughput technologies (2009)

Hornshøj, Henrik, Bendixen, Emøke, Conley, Lene N, Andersen, Pernille K, Hedegaard, Jakob, Panitz, Frank, ...

Abstract Background The recent development within high-throughput technologies for expression profiling has allowed for parallel analysis of transcriptomes and proteomes in biological systems such as...

of infB (2008)

Brian Søgaard Laursen, Jakob Hedegaard, Juan Manuel Palacios, Kim Kusk Mortensen

Structural requirements of the mRNA for intracistronic translation initiation of the enterobacterial infB gene

Gene expression profiles in liver of pigs with extreme high and low levels of androstenone (2008)

Moe, Maren, Lien, Sigbjørn, Bendixen, Christian, Hedegaard, Jakob, Hornshøj, Henrik, Berget, Ingunn, ...

Abstract Background Boar taint is the unpleasant odour and flavour of the meat of uncastrated male pigs that is primarily caused by high levels of androstenone and skatole in adipose tissue....

Analysis of the real EADGENE data set: Multivariate approaches and post analysis (Open Access publication) (2007)

Sørensen, Peter, Bonnet, Agnès, Buitenhuis, Bart, Closset, Rodrigue, Déjean, Sébastien, Delmas, Céline, ...

Abstract The aim of this paper was to describe, and when possible compare, the multivariate methods used by the participants in the EADGENE WP1.4 workshop. The first approach was for class discovery...

Analysis of the real EADGENE data set: Comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (Open Access publication) (2007)

Jaffrézic, Florence, De Koning, Dirk-Jan, Boettcher, Paul J, Bonnet, Agnès, Buitenhuis, Bart, Closset, Rodrigue, ...

Abstract A large variety of methods has been proposed in the literature for microarray data analysis. The aim of this paper was to present techniques used by the EADGENE (European Animal Disease...

The EADGENE Microarray Data Analysis Workshop (Open Access publication) (2007)

De Koning, Dirk-Jan, Jaffrézic, Florence, Lund, Mogens, Watson, Michael, Channing, Caroline, Hulsegge, Ina, ...

Abstract Microarray analyses have become an important tool in animal genomics. While their use is becoming widespread, there is still a lot of ongoing research regarding the analysis of microarray...

SNP mining porcine ESTs with MAVIANT, a novel tool for SNP evaluation and annotation (2007)

Panitz, Frank, Stengaard, Henrik, Hornshøj, Henrik, Gorodkin, Jan, Hedegaard, Jakob, Cirera, Susanna, ...

Motivation: Single nucleotide polymorphisms (SNPs) analysis is an important means to study genetic variation. A fast and cost-efficient approach to identify large numbers of novel candidates is the...

Associationer til musik i reklamer (2007)

Skov, Anne Sophie, Nielsen, Gitte Hass, Hedegaard, Jakob, Munch, Mette, Tranberg-Hansen, Morten Sejer

Projektet omhandler, hvordan individet sprogliggør oplevelsen af at høre reklamemusik uden den visuelle kobling. Der er indraget socio- og musikkulturelle teorier samt teori til afklaring af...

Molecular characterisation of the early response in pigs to experimental infection with Actinobacillus pleuropneumoniaeusing cDNA microarrays (2007)

Hedegaard, Jakob, Skovgaard, Kerstin, Mortensen, Shila, Sørensen, Peter, Jensen, Tim K, Hornshøj, Henrik, ...

Abstract Background The bacterium Actinobacillus pleuropneumoniae is responsible for porcine pleuropneumonia, a widespread, highly contagious and often fatal respiratory disease of pigs. The general...

Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags (2007)

Gorodkin, Jan, Cirera, Susanna, Hedegaard, Jakob, Gilchrist, Michael J, Panitz, Frank, Jørgensen, Claus, ...

Background Knowledge of the structure of gene expression is essential for mammalian transcriptomics research. We analyzed a collection of more than one million porcine expressed sequence tags (ESTs),...

2007 Gorodkin et Volume al. 8, Issue 4, Article R45 Open Access (2007)

Jan Gorodkin, Susanna Cirera, Jakob Hedegaard, Michael J Gilchrist, Frank Panitz, Claus Jørgensen, ...

Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags

Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags

Gorodkin, Jan, Cirera, Susanna, Hedegaard, Jakob, Gilchrist, Michael J, Panitz, Frank, Jørgensen, Claus, ...

A resource consisting of one million porcine ESTs is described, providing an essential resource for annotation, comparative genomics, assembly of the pig genome sequence, and further porcine...

The EADGENE Microarray Data Analysis Workshop (Open Access publication)

De Koning, Dirk-Jan, Jaffrézic, Florence, Lund, Mogens Sandø, Watson, Michael, Channing, Caroline, Hulsegge, Ina, ...

Microarray analyses have become an important tool in animal genomics. While their use is becoming widespread, there is still a lot of ongoing research regarding the analysis of microarray data. In...

Analysis of the real EADGENE data set: Comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (Open Access publication)

Jaffrézic, Florence, De Koning, Dirk-Jan, Boettcher, Paul J, Bonnet, Agnès, Buitenhuis, Bart, Closset, Rodrigue, ...

A large variety of methods has been proposed in the literature for microarray data analysis. The aim of this paper was to present techniques used by the EADGENE (European Animal Disease Genomics...

Analysis of the real EADGENE data set: Multivariate approaches and post analysis (Open Access publication)

Sørensen, Peter, Bonnet, Agnès, Buitenhuis, Bart, Closset, Rodrigue, Déjean, Sébastien, Delmas, Céline, ...

The aim of this paper was to describe, and when possible compare, the multivariate methods used by the participants in the EADGENE WP1.4 workshop. The first approach was for class discovery and class...