Sarsero, Doreen, Russell, Fraser D., Lynham, James A., Rabnott, Glenn, Yang, Ian, Fong, Kwun M., ...
Two forms of the activated beta(1)-adrenoceptor exist, one that is stabilized by (-)-noradrenaline and is sensitive to blockade by (-)-propranolol and another which is stabilized by partial agonists...
Sarsero, Doreen, Russell, Fraser D., Lynham, James A., Rabnott, Glenn, Yang, Ian, Fong, Kwun M., ...
Two forms of the activated beta(1)-adrenoceptor exist, one that is stabilized by (-)-noradrenaline and is sensitive to blockade by (-)-propranolol and another which is stabilized by partial agonists...
Haslam, Richard J., Lynham, James A., Fox, Joan E. B.
Human platelets that had been preincubated with 5-hydroxy[3H]tryptamine and [32P]Pi were stirred with various agents; the secretion of 5-hydroxy[3H]tryptamine from platelet granules and the...
Haslam, Richard J., Lynham, James A., Fox, Joan E. B.
Human platelets that had been preincubated with 5-hydroxy[3H]tryptamine and [32P]Pi were stirred with various agents; the secretion of 5-hydroxy[3H]tryptamine from platelet granules and the...
Kaumann, Alberto J, Lynham, James A
Mammalian hearts possess an atypical β-adrenoceptor (non-β1, non-β2, non-β3) through which (–)-4-(3-t-butylamino-2-hydroxypropoxy)benzimidazol-2-one ((–)-CGP 12177) causes cardiostimulant...
Lowe, Martin D, Lynham, James A, Grace, Andrew A, Kaumann, Alberto J
We compared the potency of 11 clinically available β-blockers as antagonists of the positive inotropic effects of (−)-isoprenaline and CGP12177 on ferret ventricular myocardium.(−)-CGP12177,...
Merritt, Janet E., Hallam, Trevor J., Brown, Anthony M., Boyfield, Isobel, Cooper, David G., Hickey, Deirdre M.B., ...
1 Octimibate, 8-[(1,4,5-triphenyl-1H-imidazol-2-yl)oxy]octanoic acid, is reported to have antihrombotic properties, This is in addition to its antihyperlipidaemic effects which are due to inhibition...