James D. Dick

Publication List Details

Period

1999 - 2004

Number

17

Co-Authors

Effect of n-octanesulphonylacetamide (OSA) on ATP and protein expression in Mycobacterium bovis BCG (2004)

Parrish, Nicole M., Ko, Chiew G., Hughes, Minerva A., Townsend, Craig A., Dick, James D.

Objective: To determine the effect on BCG of n-octanesulphonylacetamide (OSA), a novel compound of the class β-sulphonylcarboxamides, which has potent in vitro activity against pathogenic...

Effect of n-octanesulphonylacetamide (OSA) on ATP and protein expression in Mycobacterium bovis BCG (2004)

Parrish, Nicole M., Ko, Chiew G., Hughes, Minerva A., Townsend, Craig A., Dick, James D.

Objective: To determine the effect on BCG of n-octanesulphonylacetamide (OSA), a novel compound of the class β-sulphonylcarboxamides, which has potent in vitro activity against pathogenic...

Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis (1999)

Parrish, Nikki M., Kuhajda, Francis P., Heine, Henry S., Bishai, William R., Dick, James D.

Cerulenin is a potent inhibitor of fatty acid synthase (FAS) in a variety of prokaryotic and eukaryotic cells. Using a standardized mycobacterial susceptibility test, we have observed that cerulenin...

In Vitro Activity of a Novel Antimycobacterial Compound, N-Octanesulfonylacetamide, and Its Effects on Lipid and Mycolic Acid Synthesis

Parrish, Nikki M., Houston, Todd, Jones, Paul B., Townsend, Craig, Dick, James D.

β-Sulfonyl carboxamides have been proposed to serve as transition-state analogues of the β-ketoacyl synthase reaction involved in fatty acid elongation. We tested the efficacy of...

Phenotypic and Genotypic Characterization of Clinical Strains of CDC Group IVc-2

Osterhout, Gerard J., Valentine, Joan L., Dick, James D.

CDC group IVc-2 is a gram-negative, oxidase-positive, nonfermentative bacillus that has been implicated in human infections, including septicemia and peritonitis. Biochemically it most closely...

Vancomycin Resistance in Staphylococci

Srinivasan, Arjun, Dick, James D., Perl, Trish M.

Vancomycin resistance has been reported in clinical isolates of both coagulase-negative staphylococci and Staphylococcus aureus. The emerging threat of widespread vancomycin resistance poses a...

Quantitative Multiprobe PCR Assay for Simultaneous Detection and Identification to Species Level of Bacterial Pathogens

Yang, Samuel, Lin, Shin, Kelen, Gabor D., Quinn, Thomas C., Dick, James D., Gaydos, Charlotte A., ...

We describe a novel adaptation of the TaqMan PCR assay which potentially allows for highly sensitive detection of any eubacterial species with simultaneous species identification. Our system relies...

Phenotypic Switching in Candida lusitaniae on Copper Sulfate Indicator Agar: Association with Amphotericin B Resistance and Filamentation

Miller, Nancy S., Dick, James D., Merz, William G.

Candida lusitaniae is an opportunistic yeast pathogen that has the ability to develop resistance to amphotericin B (AmB). The mechanism(s) for this resistance is not well understood, although there...

In Vitro Activity of a Novel Antimycobacterial Compound, N-Octanesulfonylacetamide, and Its Effects on Lipid and Mycolic Acid Synthesis

Parrish, Nikki M., Houston, Todd, Jones, Paul B., Townsend, Craig, Dick, James D.

β-Sulfonyl carboxamides have been proposed to serve as transition-state analogues of the β-ketoacyl synthase reaction involved in fatty acid elongation. We tested the efficacy of...

Phenotypic and Genotypic Characterization of Clinical Strains of CDC Group IVc-2

Osterhout, Gerard J., Valentine, Joan L., Dick, James D.

CDC group IVc-2 is a gram-negative, oxidase-positive, nonfermentative bacillus that has been implicated in human infections, including septicemia and peritonitis. Biochemically it most closely...

Vancomycin Resistance in Staphylococci

Srinivasan, Arjun, Dick, James D., Perl, Trish M.

Vancomycin resistance has been reported in clinical isolates of both coagulase-negative staphylococci and Staphylococcus aureus. The emerging threat of widespread vancomycin resistance poses a...

Quantitative Multiprobe PCR Assay for Simultaneous Detection and Identification to Species Level of Bacterial Pathogens

Yang, Samuel, Lin, Shin, Kelen, Gabor D., Quinn, Thomas C., Dick, James D., Gaydos, Charlotte A., ...

We describe a novel adaptation of the TaqMan PCR assay which potentially allows for highly sensitive detection of any eubacterial species with simultaneous species identification. Our system relies...

Phenotypic Switching in Candida lusitaniae on Copper Sulfate Indicator Agar: Association with Amphotericin B Resistance and Filamentation

Miller, Nancy S., Dick, James D., Merz, William G.

Candida lusitaniae is an opportunistic yeast pathogen that has the ability to develop resistance to amphotericin B (AmB). The mechanism(s) for this resistance is not well understood, although there...