James D. Douglas

A randomized controlled study of human serum albumin and serum substitute supplement as protein supplements for IVF culture and the effect on live birth rates (2009)

Meintjes, Marius, Chantilis, Samuel J., Ward, David C., Douglas, James D., Rodriguez, Alfred J., Guerami, Ali R., ...

BACKGROUND It has been speculated that the addition of proteins more complex than human serum albumin (HSA) to culture media may improve IVF outcomes. Whether the expense, labor and risk of adding...

A controlled randomized trial evaluating the effect of lowered incubator oxygen tension on live births in a predominantly blastocyst transfer program (2009)

Meintjes, Marius, Chantilis, Samuel J., Douglas, James D., Rodriguez, Alfred J., Guerami, Ali R., Bookout, David M., ...

BACKGROUND The potentially damaging effect of free O2 radicals to cultured embryos may be reduced by adding scavengers to the culture media or by reducing the incubator O2 levels. However, lowering...

Antimycobacterial Activities of Isoxyl and New Derivatives through the Inhibition of Mycolic Acid Synthesis†

Phetsuksiri, Benjawan, Baulard, Alain R., Cooper, Andrea M., Minnikin, David E., Douglas, James D., Besra, Gurdyal S., ...

Isoxyl (ISO), a thiourea (thiocarlide; 4,4′-diisoamyloxythiocarbanilide), demonstrated potent activity against Mycobacterium tuberculosis H37Rv (MIC, 2.5 μg/ml), Mycobacterium bovis BCG (MIC, 0.5...

A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum

Waller, Ross F., Ralph, Stuart A., Reed, Michael B., Su, Vanessa, Douglas, James D., Minnikin, David E., ...

It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a...

Antimycobacterial Activities of Isoxyl and New Derivatives through the Inhibition of Mycolic Acid Synthesis†

Phetsuksiri, Benjawan, Baulard, Alain R., Cooper, Andrea M., Minnikin, David E., Douglas, James D., Besra, Gurdyal S., ...

Isoxyl (ISO), a thiourea (thiocarlide; 4,4′-diisoamyloxythiocarbanilide), demonstrated potent activity against Mycobacterium tuberculosis H37Rv (MIC, 2.5 μg/ml), Mycobacterium bovis BCG (MIC, 0.5...

A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum

Waller, Ross F., Ralph, Stuart A., Reed, Michael B., Su, Vanessa, Douglas, James D., Minnikin, David E., ...

It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a...