James E. Flint

Affinity maturation generates greatly improved xyloglucan-specific carbohydrate binding modules (2009)

Von Schantz, Laura, Gullfot, Fredrika, Scheer, Sebastian, Filonova, Lada, Cicortas Gunnarsson, Lavinia, Flint, James E, ...

Abstract Background Molecular evolution of carbohydrate binding modules (CBM) is a new approach for the generation of glycan-specific molecular probes. To date, the possibility of performing affinity...

The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions (2009)

Cedric Montanier, Victoria A. Money, Virginia M. R. Pires, James E. Flint, Benedita A. Pinheiro, Arun Goyal, ...

Multifunctional proteins, which play a critical role in many biological processes, have typically evolved through the recruitment of different domains that have the required functional diversity....

The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions

Montanier, Cedric, Money, Victoria A, Pires, Virginia M. R, Flint, James E, Pinheiro, Benedita A, Goyal, Arun, ...

Multifunctional proteins, which play a critical role in many biological processes, have typically evolved through the recruitment of different domains that have the required functional diversity....

Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function

Montanier, Cedric, Van Bueren, Alicia Lammerts, Dumon, Claire, Flint, James E., Correia, Marcia A., Prates, Jose A., ...

Enzymes that hydrolyze complex carbohydrates play important roles in numerous biological processes that result in the maintenance of marine and terrestrial life. These enzymes often contain...