Christopher J. Tonkin, Céline K. Carret, Manoj T. Duraisingh, Till S. Voss, Stuart A. Ralph, Mirja Hommel, ...
Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived...
Yosaatmadja, Francisca, Andrews, Katherine T, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Abstract Background Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum...
Drew, Damien R., Chesson, Joanne M., Beeson, James G., Crabb, Brendan S.
Merozoite surface protein 8 (MSP8) has shown promise as a vaccine candidate in the Plasmodium yoelii rodent malaria model and has a proposed role in merozoite invasion of erythrocytes. However, the...
Yosaatmadja, Francisca, Andrews, Katherine Thea, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Background: Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum...
Yosaatmadja, Francisca, Andrews, Katherine Thea, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Background: Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum...
Beeson, James G., Andrews, Katherine Thea, Boyle, Michelle, Duffy, Michael F., Choong, Ee Ken, Byrne, Tim J., ...
Yes
Beeson, James G., Andrews, Katherine Thea, Boyle, Michelle, Duffy, Michael F., Choong, Ee Ken, Byrne, Tim J., ...
Beeson, James G., Andrews, Katherine Thea, Boyle, Michelle, Duffy, Michael F., Choong, Ee Ken, Byrne, Tim J., ...
Promising Functional Readouts of Immunity in a Blood-Stage Malaria Vaccine Trial (2005)
Brendan S. Crabb, James G. Beeson
The authors discuss results from an early trial of a vaccine based on Plasmodium MSP-3 protein reported by Pierre Druilhe and colleagues.
Mechanisms of placental infection by Plasmodium falciparum (2000)
Typescript (photocopy) Includes bibliographical references (leaves 154-180)
Reeder, John C., Cowman, Alan F., Davern, Kathleen M., Beeson, James G., Thompson, Jennifer K., Rogerson, Stephen J., ...
Chondroitin sulfate A (CSA) is an important receptor for the sequestration of Plasmodium falciparum in the placenta, but the parasite ligand involved in adhesion has not previously been identified....
Plasmodium falciparum Rosette Formation Is Uncommon in Isolates from Pregnant Women
Rogerson, Stephen J., Beeson, James G., Mhango, Chisale G., Dzinjalamala, Fraction K., Molyneux, Malcolm E.
We examined the formation of Plasmodium falciparum erythrocyte rosettes using parasite isolates from placental or peripheral blood of pregnant Malawian women and from peripheral blood of children....
Chai, Wengang, Beeson, James G., Kogelberg, Heide, Brown, Graham V., Lawson, Alexander M.
We recently reported that Plasmodium falciparum-infected erythrocytes (IRBCs) can adhere to hyaluronic acid (HA), which appears to be a receptor, in addition to chondroitin sulfate A (CSA), for...
Reeder, John C., Hodder, Anthony N., Beeson, James G., Brown, Graham V.
Accumulation of Plasmodium falciparum-infected erythrocytes in the placenta is a key feature of maternal malaria. This process is mediated in part by the parasite ligand P. falciparum erythrocyte...
Beeson, James G., Chai, Wengang, Rogerson, Stephen J., Lawson, Alexander M., Brown, Graham V.
Adherence of parasite-infected erythrocytes (IEs) to the microvascular endothelium of various organs, a process known as sequestration, is a feature of Plasmodium falciparum malaria. This event is...
Beeson, James G., Amin, Nishal, Kanjala, Maxwell, Rogerson, Stephen J.
A feature of malaria in pregnancy is accumulation of P. falciparum-infected erythrocytes (IEs) in the placenta, which is associated with adverse outcomes for mothers and infants. Infection appears to...
Elliott, Salenna R., Duffy, Michael F., Byrne, Timothy J., Beeson, James G., Mann, Emily J., Wilson, Danny W., ...
Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated by P. falciparum...
Elliott, Salenna R., Brennan, Amy K., Beeson, James G., Tadesse, Eyob, Molyneux, Malcolm E., Brown, Graham V., ...
Antibodies targeting variant antigens on the surfaces of chondroitin sulfate A (CSA)-binding malaria-infected erythrocytes have been linked to protection against the complications of malaria in...
Promising Functional Readouts of Immunity in a Blood-Stage Malaria Vaccine Trial
Crabb, Brendan S, Beeson, James G
The authors discuss results from an early trial of a vaccine based on Plasmodium MSP-3 protein reported by Pierre Druilhe and colleagues.
Persson, Kristina E. M., Lee, Chee T., Marsh, Kevin, Beeson, James G.
Antibodies that inhibit replication of Plasmodium falciparum in erythrocytes are thought to be important both in acquired immunity to malaria and as mediators of immunity generated by candidate...
Reeder, John C., Cowman, Alan F., Davern, Kathleen M., Beeson, James G., Thompson, Jennifer K., Rogerson, Stephen J., ...
Chondroitin sulfate A (CSA) is an important receptor for the sequestration of Plasmodium falciparum in the placenta, but the parasite ligand involved in adhesion has not previously been identified....
Plasmodium falciparum Rosette Formation Is Uncommon in Isolates from Pregnant Women
Rogerson, Stephen J., Beeson, James G., Mhango, Chisale G., Dzinjalamala, Fraction K., Molyneux, Malcolm E.
We examined the formation of Plasmodium falciparum erythrocyte rosettes using parasite isolates from placental or peripheral blood of pregnant Malawian women and from peripheral blood of children....
Chai, Wengang, Beeson, James G., Kogelberg, Heide, Brown, Graham V., Lawson, Alexander M.
We recently reported that Plasmodium falciparum-infected erythrocytes (IRBCs) can adhere to hyaluronic acid (HA), which appears to be a receptor, in addition to chondroitin sulfate A (CSA), for...
Reeder, John C., Hodder, Anthony N., Beeson, James G., Brown, Graham V.
Accumulation of Plasmodium falciparum-infected erythrocytes in the placenta is a key feature of maternal malaria. This process is mediated in part by the parasite ligand P. falciparum erythrocyte...
Beeson, James G., Chai, Wengang, Rogerson, Stephen J., Lawson, Alexander M., Brown, Graham V.
Adherence of parasite-infected erythrocytes (IEs) to the microvascular endothelium of various organs, a process known as sequestration, is a feature of Plasmodium falciparum malaria. This event is...
Beeson, James G., Amin, Nishal, Kanjala, Maxwell, Rogerson, Stephen J.
A feature of malaria in pregnancy is accumulation of P. falciparum-infected erythrocytes (IEs) in the placenta, which is associated with adverse outcomes for mothers and infants. Infection appears to...
Elliott, Salenna R., Duffy, Michael F., Byrne, Timothy J., Beeson, James G., Mann, Emily J., Wilson, Danny W., ...
Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated by P. falciparum...
Elliott, Salenna R., Brennan, Amy K., Beeson, James G., Tadesse, Eyob, Molyneux, Malcolm E., Brown, Graham V., ...
Antibodies targeting variant antigens on the surfaces of chondroitin sulfate A (CSA)-binding malaria-infected erythrocytes have been linked to protection against the complications of malaria in...
Promising Functional Readouts of Immunity in a Blood-Stage Malaria Vaccine Trial
Crabb, Brendan S, Beeson, James G
The authors discuss results from an early trial of a vaccine based on Plasmodium MSP-3 protein reported by Pierre Druilhe and colleagues.
Persson, Kristina E. M., Lee, Chee T., Marsh, Kevin, Beeson, James G.
Antibodies that inhibit replication of Plasmodium falciparum in erythrocytes are thought to be important both in acquired immunity to malaria and as mediators of immunity generated by candidate...
Maier, Alexander G., Rug, Melanie, O'Neill, Matthew T., Beeson, James G., Marti, Matthias, Reeder, John, ...
A key feature of Plasmodium falciparum, the parasite causing the most severe form of malaria in humans, is its ability to export parasite molecules onto the surface of the erythrocyte. The major...
Frankland, Sarah, Elliott, Salenna R., Yosaatmadja, Francisca, Beeson, James G., Rogerson, Stephen J., Adisa, Akinola, ...
The virulence of the malaria parasite Plasmodium falciparum is related to its ability to express a family of adhesive proteins known as P. falciparum erythrocyte membrane protein 1 (PfEMP1) at the...
Persson, Kristina E.M., McCallum, Fiona J., Reiling, Linda, Lister, Nicole A., Stubbs, Janine, Cowman, Alan F., ...
Antibodies that inhibit Plasmodium falciparum invasion of erythrocytes are believed to be an important component of immunity against malaria. During blood-stage infection, P. falciparum can use...
Towards a Vaccine against Plasmodium vivax Malaria
Beeson, James G, Crabb, Brendan S
The authors discuss a new study that suggests thatPlasmodium vivax Duffy-binding protein could be a candidate antigen for developing aP. vivax vaccine.
Yosaatmadja, Francisca, Andrews, Katherine T, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Maier, Alexander G., Rug, Melanie, O'Neill, Matthew T., Brown, Monica, Chakravorty, Srabasti, Szestak, Tadge, ...
A major part of virulence for Plasmodium falciparum malaria infection, the most lethal parasitic disease of humans, results from increased rigidity and adhesiveness of infected host red cells. These...
Acquisition of Growth-Inhibitory Antibodies against Blood-Stage Plasmodium falciparum
McCallum, Fiona J., Persson, Kristina E. M., Mugyenyi, Cleopatra K., Fowkes, Freya J. I., Simpson, Julie A., Richards, Jack S., ...
Dent, Arlene E., Bergmann-Leitner, Elke S., Wilson, Danny W., Tisch, Daniel J., Kimmel, Rhonda, Vulule, John, ...
Tonkin, Christopher J, Carret, Céline K, Duraisingh, Manoj T, Voss, Till S, Ralph, Stuart A, Hommel, Mirja, ...
Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived...
Stanisic, Danielle I., Richards, Jack S., McCallum, Fiona J., Michon, Pascal, King, Christopher L., Schoepflin, Sonja, ...
Substantial evidence indicates that antibodies to Plasmodium falciparum merozoite antigens play a role in protection from malaria, although the precise targets and mechanisms mediating immunity...